Abstract
From the CH2Cl2 extract of the bark of Marsdenia cundurango Reichenb. fil. (Cortex Condurango) a mixture of basic compounds could be isolated. Repeated thin layer and column chromatography yealded two alkaloids in pure form. For Kondurangamin A, which would be the mayor alkaloid with a content of 0.0007%, the structure was determined as 3β, 14β,20-trihydroxy-11 α-nicotinoyloxy-12β-acetoxy-5α,14β-pregnane and for Kondurangamin B as 3β,11α,12β,14β-tetrahydroxy-20-nicotinoyloxy-5α,14β-pregnane.
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Die Bezeichnung der Pflanze und der Droge erfolgt gemäß dem Österreichischen Arzneibuch, 9. Ausg. (1960): Cortex Condurango-Marsdenia cundurango Reichenb. fil.-Kondurangorinde.
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Pailer, M., Ganzinger, D. Alkaloide aus Cortex Condurango. Monatshefte für Chemie 106, 37–54 (1975). https://doi.org/10.1007/BF00914498
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DOI: https://doi.org/10.1007/BF00914498