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Linkage of Pep-2 and Apk on mouse chromosome 10

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Abstract

An ethylnitrosourea (ENU)-induced electrophoretic variant of mouse PEP-2, a tripeptidase, has been used to determine the location of the structural gene on chromosome 10. Gene order and recombination frequencies were estimated as Apk-21.8±3.9%-Pep-2-3.7±2.1%-Sl. Methods for rapid determination of Apk and Pep-2 alleles by cellulose acetate electorphoresis and a valuable linkage testing stock carrying the unique Apk m and Pep-2 b alleles are described.

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Supported by Texas Agricultural Experiment Station Project 6579 and NIEHS Contract N01-ES-0-002 and EPA Contract 68-02-3626 to Research Triangle Institute.

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Womack, J.E., Ashley, S., Barnett, L.B. et al. Linkage of Pep-2 and Apk on mouse chromosome 10. Biochem Genet 24, 721–727 (1986). https://doi.org/10.1007/BF00499005

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  • DOI: https://doi.org/10.1007/BF00499005

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