Skip to main content
Log in

Tetrabenazine (nitoman) therapy of chronic spontaneous oral dyskinesia

A video- and EMG-controlled study

  • Published:
European archives of psychiatry and neurological sciences Aims and scope Submit manuscript

Summary

Therapeutic results achieved with tetrabenazine in six patients with spontaneous oral dyskinesia were evaluated by clinical rating as well as time-blind video and EMG assessment. Dramatic improvement of symptoms was observed in five of our six patients and good to satisfactory improvement in the remaining patient. The correspondance among clinical findings, EMG data, and video analysis was good. Medication was started at low doses and slowly increased. Adverse reactions (i.e., rigidity, akinesia, vasodepression) were minimal.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Bartels M, Themelis J (1983) Computerized tomography in tardive dyskinesia: Evidence of structural abnormalities in the basal ganglia system. Arch Psychiatr Nervenkr 233:371–379

    Google Scholar 

  • Brandrup E (1961) Tetrabenazine treatment in persisting dyskinesia caused by psychopharmacy. Am J Psychiatr 118:551–555

    Google Scholar 

  • Casey DE (1977) Deanol in the management of involuntary movement disorders: A review. Dis New Syst 38:7–15

    Google Scholar 

  • Delwaide PJ, Dessailles M (1977) Spontaneous buccolinguofacial dyskinesia in the elderly. Acta Neurol Scand 56:256–262

    Google Scholar 

  • Gerlach J (1977) Relationship between tardive dyskinesia, l-Dopa-induced hyperkinesia and parkinsonism. Psychopharmacology 51:259–263

    Google Scholar 

  • Godwin-Austin RB, Clark T (1971) Persistent phenothiazine dyskinesia treated with tetrabenazine. Br Med 14:25–26

    Google Scholar 

  • Kazamatsuri H, Chien C, Cole JO (1973) Long-term treatment of tardive dyskinesia with haloperidol and tetrabenazine. Am J Psychiatr 130:479–483

    Google Scholar 

  • Marsden CD (1973) Involuntary movement other than Parkinsonism. Proc R Soc Med 66:871–873

    Google Scholar 

  • Pakkenberg H (1968) The effect of tetrabenazine in some hyperkinetic syndromes. Acta Neurol Scand 44:391–393

    Google Scholar 

  • Pakkenberg H, Fog R (1974) Spontaneous oral dyskinesia. Arch Neurol 31:352–353

    Google Scholar 

  • Rüther E, Bindig R, Ther P (1978) Neuropharmakotherapie dyskinetischer Syndrome. Pharmakotherapie 1:200–210

    Google Scholar 

  • Schumm F, Dichgans J, Zeller E (1981) Spontane orale Dyskinesien: Erfolgreiche Therapie mit Tetrabenazin (Nitoman). Arch Psychiatr Nervenkr 230:315–323

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bartels, M., Zeller, E. Tetrabenazine (nitoman) therapy of chronic spontaneous oral dyskinesia. Eur Arch Psychiatr Neurol Sci 234, 172–174 (1984). https://doi.org/10.1007/BF00461557

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00461557

Key words

Navigation