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Demonstration of Epstein-Barr virus DNA in a previously healthy boy with fulminant hepatic failure

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Abstract

A previously healthy 9-year-old boy died from acute liver failure during an acute Epstein-Barr virus infection. Epstein-Barr virus DNA could be demonstrated in the liver by Southern blot — and by in situ hybridization techniques. The identification of the virus in the liver suggests a causal relation between the Epstein-Barr virus and the acute massive liver cell necrosis.

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Abbreviations

EBV:

Epstein-Barr virus

ALT:

alanine amniotransferase

KBR:

complement binding reactions

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Deutsch, J., Wolf, H., Becker, H. et al. Demonstration of Epstein-Barr virus DNA in a previously healthy boy with fulminant hepatic failure. Eur J Pediatr 145, 94–98 (1986). https://doi.org/10.1007/BF00441865

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  • DOI: https://doi.org/10.1007/BF00441865

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