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Sleep deprivation deficits and their reversal by d-and l-amphetamine

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Abstract

Vigilance performance, waking EEG patterns and mood were studied before and after one night of sleep deprivation in normal males. The effects of d-amphetamine 10 mg, l-amphetamine 10 mg and placebo on these measures were compared. Changes were found in all three measures after one night of sleep-deprivation. d-Amphetamine was more powerful than l-amphetamine in reversing sleep deprivation effects on vigilance and on waking EEG.

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Hartmann, E., Orzack, M.H. & Branconnier, R. Sleep deprivation deficits and their reversal by d-and l-amphetamine. Psychopharmacology 53, 185–189 (1977). https://doi.org/10.1007/BF00426490

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  • DOI: https://doi.org/10.1007/BF00426490

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