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Early detection of glaucoma by longitudinal monitoring of the optic disc structure

  • Clinical Investigations
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Abstract

Computerized disc analysis (optic nerve-head analyzer, Rodenstock) and automated perimetry (Octopus 2000R, program G1) were used for the longitudinal monitoring of 25 subjects with elevated intraocular pressure (47 eyes). The mean follow-up time was 17.9 months (range, 12–30 months). The average number of disc examinations per eye during the follow-up period was 4.4 (range, 3–7). A progressive decrease in neuroretinal rim area was observed in 8 of 47 eyes. This continuous decrease is nonphysiological and must be interpreted as a valid sign of ongoing glaucomatous damage. It apparently precedes visual field defects, as all eyes showing continuous loss of neuroretinal rim area have had normal visual fields up to the present. Of the remaining 47 eyes, 21 showed a slight increase or no change in neuroretinal rim area. These eyes obviously did not suffer from progressive glaucomatous nerve-head damage during the follow-up period. A total of 18 eyes showed either considerable fluctuations or only a slight decrease in neuroretinal rim area; no decision can yet be made as to whether or not these eyes actually suffered glaucomatous damage.

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References

  1. Airaksinen PJ, Drance SM, Schulzer M (1985) Neuroretinal rim area in early glaucoma. Am J Ophthalmol 99:1–14

    Google Scholar 

  2. Anderson DR (1985) The optic nerve in glaucoma. In: Duane TD, Jaeger EA (eds) Clinical opthalmology, vol 3, Chap. 48, Harper & Row, Philadelphia, pp 1–12

    Google Scholar 

  3. Armaly MF (1969) The correlation between appearance of the optic cup and visual function. Ophthalmology 73:898–913

    Google Scholar 

  4. Betz P, Camps F, Collignon-Brach J, Lavergne G, Weekers R (1982) Biometric study of the disc cup in open angle glaucoma. Graefe's Arch Clin Exp Ophthalmol 218:70–74

    Google Scholar 

  5. Bishop KI, Werner EB, Krupin T, Kozart DM, Beck SR, Nunan Fa, Wax MB (1988) Variability and reproducibility of optic disc topographic measurements with the Rodenstock optic nerve head analyzer. Am J Ophthalmol 106:696–702

    Google Scholar 

  6. Britton RJ, Drance SM, Schulzer M, Douglas GR, Mawson DK (1987) The area of the neuroretinal rim of the optic nerve in normal eyes. Am J Ophthalmol 103:497–504

    Google Scholar 

  7. Caprioli MD, Miller JM (1988) Videographic measurements of optic nerve topography in glaucoma. Invest Ophthalmol Vis Sci 29:1294–1298

    Google Scholar 

  8. Caprioli MD, Miller JM (1988) Correlation of structure and function in glaucoma. Ophthalmology 95:723–727

    Google Scholar 

  9. Caprioli J, Klingbeil U, Sears M, Bryony P (1986) Reproducibility of optic disc measurements with computerized analysis of stereoscopic video images. Arch Ophthalmol 104:1035–1039

    Google Scholar 

  10. Caprioli J, Miller JM, Sears M (1987) Quantitative evaluation of the optic nerve head in patients with unilateral visual field loss from primary open angle glaucoma. Ophthalmology 94:1484–1487

    Google Scholar 

  11. Cornsweet TN, Hersh S, Humphries JC, Beesmer RJ, Cornsweet DW (1983) Quantification of the shape and color of the optic nerve head. In: Brenin GM, Siegel IM (eds) Advances in diagnostic visual optics. Springer, Berlin Heidelberg New York, pp 141–149

    Google Scholar 

  12. Dandona L, Quigley HA, Jampel HD (1989) Reliability of optic nerve head topographic measurements with computerized image analysis. Am J Ophthalmol 108:414–421

    Google Scholar 

  13. Flammer J, Jenni F, Bebie H, Keller B (1987) The octopus glaucoma G1 program. Glaucoma 9:67–72

    Google Scholar 

  14. Funk J, Grehn F (1989) Correlation between neuroretinal rim area and age in normal subjects. Graefe's Arch Clin Exp Ophthalmol 227:544–548

    Google Scholar 

  15. Funk J, Bornscheuer C, Grehn F (1988) Neuroretinal rim area and visual field in glaucoma. Graefe's Arch Clin Exp Ophthalmol 226:431–434

    Google Scholar 

  16. Funk J, Bornscheuer C, Grehn F (1988) Zusammenhang zwischen neuroretinalem Randsaum der Papille und Gesichtsfeld beim Glaukom. Fortschr Ophthalmol 85:452–456

    Google Scholar 

  17. Gramer E, Klingbeil U (1986) Quantitative Papillenanalyse mit dem Optic Nerve Head Analyzer. Z Prakt Augenheilkd 7:30–36

    Google Scholar 

  18. Jonas JB, Gusek GC, Guggenmoos-Holzmann I, Naumann GOH (1988) Variability of real dimensions of normal human optic discs. Graefe's Arch Clin Exp Ophthalmol 226:332–336

    Google Scholar 

  19. Kruse FE, Burk ROW, Völcker HE, Zinser G, Harbath U (1989) Reproducibility of topographic measurements of the optic nerve head with laser tomographic scanning. Ophthalmology 96:1320–1324

    Google Scholar 

  20. Mikelberg FS, Duoglas GR, Schulzer M, Cornsweet TN, Wijsman K (1984) Reliability of optic topographic measurements recorded with a video-ophthalmograph. Am J Ophthalmol 98:98–102

    Google Scholar 

  21. Motolko M, Drance SM (1981) Features of the optic disc in preglaucomatous eyes. Arch Ophthalmol 99:1992–1994

    Google Scholar 

  22. Odberg T, Riise D (1985) Early diagnosis of glaucoma. Acta Ophthalmol 63:257–263

    Google Scholar 

  23. Pederson JE, Anderson DR (1980) The mode of progressive disc cupping in ocular hypertension and glaucoma. Arch Ophthalmol 98:490–495

    Google Scholar 

  24. Peli E (1989) Electro-optic fundus imaging. Surv Ophthalmol 34:113–122

    Google Scholar 

  25. Shields MB, Martone JF, Shelton AR, Ollie AR, MacMillan J (1987) Reproducibility of topographic measurements with the optic nerve head analyzer. Am J Ophthalmol 104:581–586

    Google Scholar 

  26. Shields MB, Tiedeman JS, Miller KN, Hickingbotham D, Ollie AR (1989) Accuracy of topographic measurements with the optic nerve head analyzer. Am J Ophthalmol 107:273–279

    Google Scholar 

  27. Sommer A, Pollack I, Maumemee AE (1979) Optic disc parameters and onset of glaucomatous field loss. Arch Ophthalmol 97:1444–1448

    Google Scholar 

  28. Varma R, Spaeth GL (1988) The PAR IS 2000: a new system for retinal digital image analysis. Ophthalmic Surg 19:183–191

    Google Scholar 

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Funk, J. Early detection of glaucoma by longitudinal monitoring of the optic disc structure. Graefe's Arch Clin Exp Ophthalmol 229, 57–61 (1991). https://doi.org/10.1007/BF00172262

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  • DOI: https://doi.org/10.1007/BF00172262

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