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Epidemiology, Risk Factors, and Clinical Manifestation

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Gastrointestinal Cancer

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Abstract

Esophageal cancers are generally classified as squamous cell carcinoma (SCC) and adenocarcinoma (ADC). Both histopathological types have a similar clinical manifestation, but different characteristics, including tumor location and risk factors. For most of the twentieth century, SCC predominated; however, recently, the incidence of ADC arising from Barrett’s esophagus (BE) has dramatically increased in Western countries. However, SCC is still the main histopathological type in most countries; and SCC, especially, comprises more than 90% of all cases of esophageal cancer in Eastern Asian countries, including Korea, Japan, and China. The epidemiology, risk factors, and clinical manifestation of SCC and ADC of the esophagus and gastroesophageal junction (GEJ) will be reviewed here.

Gwang Ha Kim is the lead author of this chapter.

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Authors and Affiliations

  1. Department of Internal Medicine, Korea University Anam Hospital, Seoul, Korea (Republic of)

    Hoon Jai Chun

  2. Department of Internal Medicine, Kosin University Gospel Hospital, Busan, Korea (Republic of)

    Seun Ja Park

  3. Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Kyonggi-do, Korea (Republic of)

    Yun Jeong Lim

  4. Department of Internal Medicine, Yonsei University Severance Hospital, Seoul, Korea (Republic of)

    Si Young Song

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© 2023 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Chun, H.J., Park, S.J., Lim, Y.J., Song, S.Y. (2023). Epidemiology, Risk Factors, and Clinical Manifestation. In: Gastrointestinal Cancer. Springer, Singapore. https://doi.org/10.1007/978-981-99-0815-8_12

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  • DOI: https://doi.org/10.1007/978-981-99-0815-8_12

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  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-99-0814-1

  • Online ISBN: 978-981-99-0815-8

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