Abstract
Psychosis and mania are psychiatric disorders wherein there is loss of insight for the affected patients. While the exact pathophysiology behind psychosis has not been confirmed, the dopaminergic theory still forms the frontline of management. Antipsychotic agents can be broadly divided into typical and atypical, mainly based on their affinity towards dopaminergic receptors. While the typical antipsychotics are still used in emergencies, the atypical agents are preferred due to their added safety margin. The agents used in the management of psychosis are detailed in this chapter. The chapter also explains the drugs that are used to manage mania and bipolar disorder. While lithium is considered to be the classical mood stabilizer, there have been several other newer agents that are used in bipolar disorder.
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Bibliography
Geddes JR, Miklowitz DJ (2013) Treatment of bipolar disorder. Lancet 381(9878):1672–1682
Meltzer HY (2013) Update on typical and atypical antipsychotic drugs. Annu Rev Med 64:393–406
Scarff JR, Casey DA (2011) Newer oral atypical antipsychotic agents: a review. P T 36(12):832–838
Shah N, Grover S, Rao GP (2017) Clinical practice guidelines for Management of Bipolar Disorder. Indian J Psychiatry 59(Suppl 1):S51–S66
Worrel JA, Marken PA, Beckman SE, Reuhter VL (2000) Atypical antipsychotic agents: a critical review. Am J Health Syst Pharm 57(3):238–255
Young LT (2004) What exactly is a mood stabilizer? J Psychiatry Neurosci 29(2):87–88
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Arivazhahan, A. (2021). Drug Therapy of Psychosis and Mania. In: Paul, A., Anandabaskar, N., Mathaiyan, J., Raj, G.M. (eds) Introduction to Basics of Pharmacology and Toxicology. Springer, Singapore. https://doi.org/10.1007/978-981-33-6009-9_9
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DOI: https://doi.org/10.1007/978-981-33-6009-9_9
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