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Alginate-Based Drug Delivery Systems for Respiratory Disease

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Book cover Natural Polymeric Materials based Drug Delivery Systems in Lung Diseases
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Abstract

Alginate obtained from brown seaweeds has numerous biomedical applications. It is an excellent excipient in drug delivery systems, serving as a stability agent in different types of pharmaceutical formulations. Alginates have significant applications in nanomedicines, such as dendrimers, nanocrystals, emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles, and have more advantages in comparison to conventional medications in terms of efficacy, safety, pharmacokinetic/pharmacodynamic property, and physicochemical properties. Polymer-based drug delivery approaches have gained lot of interest in past decade. Newer techniques and innovations have given us opportunity to utilize natural biopolymers for various life-threatening diseases. Respiratory diseases being one of the leading causes of death in recent years which include asthma, chronic obstructive pulmonary disease (COPD), pulmonary fibrosis, pneumonia, and lung cancer that results in decline in lung function. Recent advances in nanotechnology have shed new light on the current treatment of chronic airway disease. This chapter is focused on the management of respiratory disease with more emphasis on the recent advances in nanotechnology-based therapeutics utilizing alginate polymers.

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Gupta, R., Dan, D., Singh, A., Nimisha (2023). Alginate-Based Drug Delivery Systems for Respiratory Disease. In: Dureja, H., Adams, J., Löbenberg, R., Andreoli Pinto, T.d.J., Dua, K. (eds) Natural Polymeric Materials based Drug Delivery Systems in Lung Diseases. Springer, Singapore. https://doi.org/10.1007/978-981-19-7656-8_19

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