Abstract
Dolomiaea costus (Syn. Saussurea costus), commonly known as the costus, Indian costus, kut, or putschuk, is a species of thistle native to South Asia and a member of the Dolomiaea genus. Studies conducted on Dolomiaea species around the globe have demonstrated the existence of bioactive secondary metabolites including polyphenols, flavonoids, lignans, sesquiterpenoids, and lactones. The goal of this chapter is to compile all the scientific data on D. costus’ traditional usage, bioactive chemical components, and pharmacological properties. In summation, our investigation shows that D. costus has a wide variety of bioactive substances contributing its anti-inflammatory, antibacterial, antioxidant, and anticancer activities. To provide greater scientific support for their traditional applications, more in vivo and clinical research for mechanism-based pharmacological evaluation should be conducted in the future.
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Mishra, A.P., Nigam, M., Devkota, H.P., Matsabisa, M.G. (2022). Dolomiaea costus (Falc.) Kasana and A. K. Pandey: Ethnomedicinal Uses, Bioactive Chemical Constituents, and Pharmacological Activities. In: Devkota, H.P., Aftab, T. (eds) Medicinal Plants of the Asteraceae Family. Springer, Singapore. https://doi.org/10.1007/978-981-19-6080-2_10
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