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Role of Full Endoscopic Procedures in Management of Tuberculosis of Spine

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Tuberculosis of the Spine
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Abstract

The treatment of spinal tuberculosis in the present era has become more complex because of the rise in immunocompromised conditions like HIV, diabetes mellitus and presence of drug-resistant tuberculosis. Tissue biopsy is always the mainstay treatment in uncomplicated spinal TB, whereas surgery is necessary in complicated spinal TB. Minimally invasive spine surgeries (MIS) are commonly used in the management of degenerative spinal conditions. Full endoscopic surgeries, a type of MIS surgeries, are already established techniques in the management of disc herniations and spinal stenosis. In this chapter we discuss in detail the role of full endoscopy in obtaining tissue biopsy, their efficacy in debridement of the lesion and instrumented fusion when necessary in select cases. We have compared their effectiveness with current standard procedures like CT-guided biopsy and open surgical procedures like anterior debridement and fusion. We have also discussed the indications and limitations of these procedures.

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References

  1. Jain AK. Tuberculosis of the spine: a fresh look at an old disease. J Bone Joint Surg Br Vol. 2010;92(7):905.

    Article  CAS  Google Scholar 

  2. Gan F, Jiang J, Xie Z, Huang S, Li Y, Chen G, Tan H. Minimally invasive direct lateral interbody fusion in the treatment of the thoracic and lumbar spinal tuberculosis Mini-DLIF for the thoracic and lumbar spinal tuberculosis. BMC Musculoskelet Disord. 2018;19:283.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Zhang Z, Fei L, Qiang Z, Fei D, Dong S, Xu J. The outcomes of chemotherapy only treatment on mild spinal tuberculosis. J Orthop Surg Res. 2016;11(1):1–8.

    Article  Google Scholar 

  4. Faciszewski T, Winter RB, Lonstein JE, Denis F, Johnson L. The surgical and medical perioperative complications of anterior spinal fusion surgery in the thoracic and lumbar spine in adults. A review of 1223 procedures. Spine. 1995;20(14):1592–9.

    Article  CAS  PubMed  Google Scholar 

  5. Tuli SM. Tuberculosis of the skeletal system. 4th ed. New Delhi, ND: Jaypee Brothers Medical Publishers (P) Ltd; 2010.

    Book  Google Scholar 

  6. Gautam MP, Karki P, Rijal S, Singh R. Pott’s spine and Pott’s paraplegia. J Nep Med Assoc. 2005;44(159):106–15.

    CAS  Google Scholar 

  7. Turgut M. Spinal tuberculosis (Pott’s disease): its clinical presentation, surgical management, and outcome. A survey study on 694 patients. Neurosurg Rev. 2001;24:8–13.

    Article  CAS  PubMed  Google Scholar 

  8. Garg N, Vohra R. Minimally invasive surgical approaches in the management of tuberculosis of the thoracic and lumbar spine. Clin Orthop Relat Res. 2014;472:1855–67.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Chen H-C, Huang T-L, Tsou Y-JCH-K, Lin W-C, Hung C-H, Tsai C-H, Hsu H-C, Chen H-T. Clinical study: a minimally invasive endoscopic surgery for infectious spondylodiscitis of the thoracic and upper lumbar spine in immunocompromised patients. Biomed Res Int. 2015;2015:780451. https://doi.org/10.1155/2015/780451. Epub 2015 Jul 26.

  10. Lin C-Y, Chang C-C, Chen Y-J, Tsai C-H, Tsou H-K, Lin C-S, Ho M-W, Chen H-T, Hsu H-C. New strategy for minimally invasive endoscopic surgery to treat infectious spondylodiscitis in the thoracolumbar spine. Pain Physician. 2019;22:281–93.

    PubMed  Google Scholar 

  11. Garg RK, Somvanshi DS. Spinal tuberculosis: a review. J Spinal Cord Med. 2011;34:440–54.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Jayaswal A, Upendra B, Ahmed A, Chowdhury B, Kumar A. Video-assisted thoracoscopic anterior surgery for tuberculous spondylitis. Clin Orthop Relat Res. 2007;460:100–7.

    Article  PubMed  Google Scholar 

  13. Xiong W, Yu B, Zhang Y, Wang C, Tang X, Cao H, Zhang X, Song Q, Tan F, Tan J. Minimally invasive far lateral debridement combined with posterior instrumentation for thoracic and lumbar tuberculosis without severe kyphosis. J Orthop Surg Res. 2020;15:221.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Moon MS. Tuberculosis of the spine. Controversies and a new challenge. Spine (Phila Pa 1976). 1997;22:1791–7.

    Article  CAS  Google Scholar 

  15. Tuli SM. Severe kyphotic deformity in tuberculosis of the spine. Int Orthop. 1995;19:327–31.

    Article  CAS  PubMed  Google Scholar 

  16. Wang X, Pang X, Wu P, Luo C, Shen X. One-stage anterior debridement, bone grafting and posterior instrumentation vs. single posterior debridement, bone grafting, and instrumentation for the treatment of thoracic and lumbar spinal tuberculosis. Eur Spine J. 2014;23:830–7.

    Article  PubMed  Google Scholar 

  17. Ha KY, Kim YH, Seo JY, Bae SH. Percutaneous posterior instrumentation followed by direct lateral interbody fusion for lumbar infectious spondylitis. J Spinal Disord Tech. 2013;26:E95–100.

    Article  PubMed  Google Scholar 

  18. Wang QY, Huang MG, Ou DQ, Xu YC, Dong JW, Yin HD, Chen W, Rong LM. One-stage extreme lateral interbody fusion and percutaneous pedicle screw fixation in lumbar spine tuberculosis. J Musculoskelet Neuronal Interact. 2017;17:450–5.

    PubMed  PubMed Central  Google Scholar 

  19. Lü G, Wang B, Li J, Liu W, Cheng I. Anterior debridement and reconstruction via thoracoscopy-assisted mini-open approach for the treatment of thoracic spinal tuberculosis: minimum 5-year follow-up. Eur Spine J. 2012;21:463–9.

    Article  PubMed  Google Scholar 

  20. Duan K, Qin Y, Ye J, Zhang W, Hu X, Zhou J, Gao L, Tang Y. Percutaneous endoscopic debridement with percutaneous pedicle screw fixation for lumbar pyogenic spondylodiscitis: a preliminary study. Int Orthop. 2020;44:495–502.

    Article  PubMed  Google Scholar 

  21. Faciszewski T, Winter RB, Lonstein JE, Denis F, Johnson L. The surgical and medical perioperative complications of anterior spinal fusion surgery in the thoracic and lumbar spine in adults. A review of 1223 procedures. Spine (Phila Pa 1976). 1995;20:1592–9.

    Article  CAS  Google Scholar 

  22. Fessler RG, Sturgill M. Review: complications of surgery for thoracic disc disease. Surg Neurol. 1998;49:609–18.

    Article  CAS  PubMed  Google Scholar 

  23. Graham AW III, Mac Millan M, Fessler RG. Lateral extra-cavitary approach to the thoracic and thoracolumbar spine. Orthopedics. 1997;20:605–10.

    Article  PubMed  Google Scholar 

  24. Yang SC, Fu TS, Chen LH, Chen WJ, Tu YK. Identifying pathogens of spondylodiscitis: percutaneous endoscopy or CT-guided biopsy. Clin Orthop Relat Res. 2008;466:3086–92.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Hanaoka N, Kawasaki Y, Sakai T, Nakamura T, Nanamori K, Nakamura E, et al. Percutaneous drainage and continuous irrigation in patients with severe pyogenic spondylitis, abscess formation, and marked bone destruction. J Neurosurg Spine. 2006;4:374–9.

    Article  PubMed  Google Scholar 

  26. Nagata K, Ohashi T, Ariyoshi M, Sonoda K, Imoto H, Inoue A. Percutaneous suction aspiration and drainage for pyogenic spondylitis. Spine. 1998;15:1600–6.

    Article  Google Scholar 

  27. Onik G, Shang Y, Maroon JC. Automated percutaneous biopsy in postoperative diskitis: a new method. Am J Neuroradiol. 1990;11:391–3.

    CAS  PubMed  PubMed Central  Google Scholar 

  28. Tofuku K, Koga H, Yone K, Komiya S. Continuous irrigation in pyogenic spondylitis accompanied by iliopsoas abscess. Spine. 2007;15:E382–7.

    Article  Google Scholar 

  29. Yu WY, Siu C, Wing PC, Schweigel JF, Jetha N. Percutaneous suction aspiration for osteomyelitis: report of two cases. Spine. 1991;16:198–202.

    CAS  PubMed  Google Scholar 

  30. J Jiang, F Gan, H Tan, Z Xie, X Luo, G Huang, Y Li, S Huang. Effect of computer navigation-assisted minimally invasive direct lateral interbody fusion in the treatment of patients with lumbar tuberculosis A retrospective study. Medicine (Baltimore). 2018;97(48):e13484. https://doi.org/10.1097/MD.0000000000013484. PMID: 30508977; PMCID: PMC6283231.

  31. Fouquet B, Goupille P, Jattiot F, Cotty P, Lapierre F, Valat JP, Amouroux J, Benatre A. Discitis after lumbar disc surgery: features of “aseptic” and “septic” forms. Spine. 1992;17:356–8.

    Article  CAS  PubMed  Google Scholar 

  32. Wu D, Sun J, Fan W, Yuan F. Unilateral or Bilateral Percutaneous Endoscopic Debridement and Lavage Treatment for Lumbar Spinal Tuberculosis. World Neurosurg. 2020;140:e73-e80. https://doi.org/10.1016/j.wneu.2020.04.132. Epub 2020 Apr 25. PMID: 32344133.

  33. Yang JS, Chu L, Deng R, Chen CM, Wang XF, Xie PG, Yu KX, Rong LM, Hao DJ, Wei JM, Deng ZL. Treatment of Single-Level Thoracic Tuberculosis by Percutaneous Endoscopic Débridement and Allograft via the Transforaminal Approach Combined with Percutaneous Pedicle Screw Fixation: A Multicenter Study with a Median Follow-Up of 36 Months. World Neurosurg. 2019;122:e1472–e1481. https://doi.org/10.1016/j.wneu.2018.11.087. Epub 2018 Nov 19. PMID: 30465947.

  34. Lin GX, Kim JS, Sharma S, Sun LW, Wu HH, Chang KS, Chen YC, Chen CM. Full endoscopic discectomy, debridement, and drainage for high-risk patients with spondylodiscitis. World Neurosurg. 2019;127:e202–11.

    Article  PubMed  Google Scholar 

  35. Yu CH. Full-endoscopic debridement and drainage treating spine infection and psoas muscle abscess. J Spine Surg. 2020;6(2):415–23.

    Article  PubMed  PubMed Central  Google Scholar 

  36. Wang X, Zhou S, Bian Z, Li M, Wu J, Hou C, Zhu L. Unilateral percutaneous endoscopic debridement and drainage for lumbar infectious spondylitis. J Orthop Surg Res. 2018;13:306.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Kim BJ, Lee JW, Kim SJ, et al. Diagnostic yield of fluoroscopy-guided biopsy for infectious spondylitis. AJNR Am J Neuroradiol. 2013;34:233–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  38. Chew FS, Kline MJ. Diagnostic yield of CT-guided percutaneous aspiration procedures in suspected spontaneous infectious disk-itis. Radiology. 2001;218:211–4.

    Article  CAS  PubMed  Google Scholar 

  39. Parker LM, McAfee PC, Fedder IL, Weis JC, Geis WP. Minimally invasive surgical techniques to treat spine infections. Orthop Clin North Am. 1996;27:183–99.

    Article  CAS  PubMed  Google Scholar 

  40. Rankine JJ, Barron DA, Robinson P, Millner PA, Dickson RA. Therapeutic impact of percutaneous spinal biopsy in spinal infection. Postgrad Med J. 2004;80:607–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  41. Staatz G, Adam GB, Keulers P, Vorwerk D, Gunther RW. Spondylodiskitic abscesses: CT-guided percutaneous catheter drainage. Radiology. 1998;208:363–7.

    Article  CAS  PubMed  Google Scholar 

  42. Vinicoff PG, Gutschik E, Hansen SE, Karle A, Rieneck K. CT-guided spinal biopsy in spondylodiscitis. [in Danish]. Ugeskr Laeger. 1998;160:5931–4.

    CAS  PubMed  Google Scholar 

  43. Ito M, Abumi K, Kotani Y, Kadoya K, Minami A. Clinical outcome of posterolateral endoscopic surgery for pyogenic spondylodiscitis: results of 15 patients with serious comorbid conditions. Spine. 2007;32:200–6.

    Article  PubMed  Google Scholar 

  44. Yang SC, Fu TS, Chen LH, Niu CC, Lai PL, Chen WJ. Percutaneous endoscopic discectomy and drainage for infectious spondylitis. Int Orthop. 2007;31:367–73.

    Article  PubMed  Google Scholar 

  45. Xu Z, Zheng Y. Percutaneous endoscopic debridement and irrigation for thoracic infections. Rev Assoc Med Bras. 2018;64(6):518–24.

    Article  PubMed  Google Scholar 

  46. Chen HC, Huang TL, Chen YJ, Tsou HK, Lin WC, Hung CH, Tsai CH, Hsu HC, Chen HT. A Minimally invasive endoscopic surgery for infectious spondylodiscitis of the thoracic and upper lumbar spine in immunocompromised patients. Biomed Res Int. 2015;2015:780451.

    PubMed  PubMed Central  Google Scholar 

  47. Yang S-C, Chiu Y-C, Chen H-S, Kao Y-H, Jou I-M, Yuan-Kun T. Percutaneous endoscopic debridement and drainage for the treatment of instrumented lumbar spine infection. J Orthop Surg. 2019;27(3):1–7.

    Article  CAS  Google Scholar 

  48. Fu TS, Wang YC, Lin TY, Chang CW, Wong CB, Su JY. Comparison of percutaneous endoscopic surgery and traditional anterior open surgery for treating lumbar infectious spondylitis. J Clin Med. 2019;8(9):1356.

    Article  CAS  PubMed Central  Google Scholar 

  49. Mao Y, Yang L, Cui X. Percutaneous endoscopic debridement and drainage for spinal infection: systemic review and meta-analysis. Pain Physician. 2019;22:323–30.

    PubMed  Google Scholar 

  50. Hsu L-C, Tseng T-M, Yang S-C, Chen H-S, Yen C-Y, Tu Y-K. Bilateral portal percutaneous endoscopic debridement and lavage for lumbar pyogenic spondylitis. Orthopedics. 2015;38(10):e856–63.

    Article  PubMed  Google Scholar 

  51. Yang SC, Fu TS, Chen HS, Kao YH, Yu SW, Tu YK. Minimally invasive endoscopic treatment for lumbar infectious spondylitis: a retrospective study in a tertiary referral center. BMC Musculoskelet Disord. 2014;15:105.

    Article  PubMed  PubMed Central  Google Scholar 

  52. Leu HF, Hauser RK. Percutaneous endoscopic lumbar spine fusion. Neurosurg Clin N Am. 1996 Jan;7(1):107–17.

    Article  CAS  PubMed  Google Scholar 

  53. Osman SG. Endoscopic transforaminal decompression, interbody fusion, and percutaneous pedicle screw implantation of the lumbar spine: a case series report. Int J Spine Surg. 2012;6:157–66.

    Article  PubMed  PubMed Central  Google Scholar 

  54. Liu J, Liu D, An G, et al. Clinical outcomes of percutaneous endoscopic debridement and drainage combined with percutaneous pedicle screw fixation for the treatment of infective spondylodiscitis. Res Square. 2020; https://doi.org/10.21203/rs.3.rs-23766/v1.

  55. Choi E-J, Kim S-Y, Kim H-G, Shon H-S, Kim T-K, Kim K-H. Percutaneous endoscopic debridement and drainage with four different approach methods for the treatment of spinal infection. Pain Physician. 2017;20:E933–40.

    PubMed  Google Scholar 

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Lokhande, P.V. (2022). Role of Full Endoscopic Procedures in Management of Tuberculosis of Spine. In: Dhatt, S.S., Kumar, V. (eds) Tuberculosis of the Spine. Springer, Singapore. https://doi.org/10.1007/978-981-16-9495-0_23

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  • DOI: https://doi.org/10.1007/978-981-16-9495-0_23

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