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Medicinal Plants: A Perspective on Their Application in the African Smallholder Aquaculture Farms

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Abstract

This chapter reviews the role of medicinal plants as growth enhancers, immunostimulants, disease-controlling agents, anaesthetics, and sex reversal agents in aquaculture and perspectives on their application in African aquaculture smallholder farms. The statement that aquaculture is one of the significant contributors to global food security is unquestionable. However, increased intensification of this sector compromises its sustainability as some of the challenges such as increased fish stress, disease outbreaks, poor fish growth, and feed quality affect its performance. Therefore, effort has been made for the fish farmers to take advantage of the benefits associated with intensive aquaculture systems. Among the remedies, medicinal plants are believed to be one of the best innovations with the potential to contribute to a sustainable aquaculture sectors as they can be used as growth promoters, feed utilization enhancers, immunostimulants, anti-depressants, anaesthetics, sex reversal agents, antimicrobial agents, among others. Since they are usually cheap, readily available across the world, more biodegradable, and simple to use compared to pharmaceutical drugs, they are more appropriate for smallholder aquaculture farmers in Africa. However, for the African smallholder aquaculture farmers to take advantage of the benefits associated with medicinal herbs, more studies are needed to validate and optimize the effects of numerous herbs on African aquaculture species.

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References

  • Abd El-Naby AS, El Asely AM, Amin AA, Samir F, El-Ashram A, Dawood MAO (2020) Miswak (Salvadora persica) modulated the growth performance, antioxidative response, and histopathological damage induced by zinc toxicity in Nile tilapia (Oreochromis niloticus). Environ Sci Pollut Res 27(25):31918–31932. https://doi.org/10.1007/s11356-020-09429-1

    Article  CAS  Google Scholar 

  • Abdelkhalek NK, Risha E, El-Adl MA, Salama MF, Dawood MAO (2020) Antibacterial and antioxidant activity of clove oil against Streptococcus iniae infection in Nile tilapia (Oreochromis niloticus) and its effect on hepatic hepcidin expression. Fish Shellfish Immunol 104:478–488. https://doi.org/10.1016/j.fsi.2020.05.064

    Article  CAS  PubMed  Google Scholar 

  • Abdel-Latif HMR, Khalil RH (2014) Evaluation of two phytobiotics, Spirulina platensis and Origanum vulgare extract on growth, serum antioxidant activities and resistance of Nile tilapia (Oreochromis niloticus) to pathogenic Vibrio alginolyticus. Int J Fish Aquat Stud 1(5):250–255

    Google Scholar 

  • Abdel-Tawwab M (2015) The use of American Ginseng (Panax quinquefolium) in practical diets for Nile tilapia (Oreochromis niloticus): resistance to waterborne copper toxicity. Aquac Res 46(4):1001–1006

    Article  CAS  Google Scholar 

  • Abdel-Tawwab M, Ahmad MH, Seden MEA, Sakr SFM (2010) Use of Green Tea, Camellia sinensis L., in practical diet for growth and protection of Nile Tilapia, Oreochromis niloticus (L.), against Aeromonas hydrophila infection. J World Aquac Soc 41:203–213. https://doi.org/10.1111/j.1749-7345.2010.00360.x

    Article  Google Scholar 

  • Abdel-Tawwab M, Sharafeldin KM, Mosaad MNM, Ismaiel NEM (2015) Coffee bean in common carp, Cyprinus carpio L. diets: effect on growth performance, biochemical status, and resistance to waterborne zinc toxicity. Aquaculture 448:207–213. https://doi.org/10.1016/j.aquaculture.2015.06.010

    Article  CAS  Google Scholar 

  • Abdul Kader Mydeen KP, Haniffa MA (2011) Evaluation of antibacterial activity of medicinal plants on fish pathogen Aeromonas hydrophila. J Res Biol 1:1–5

    Google Scholar 

  • Abodahab N (2015) Effect of Syzygium aromaticum and Rosmarinus officinalis extracts on Giardia lamblia and Streptococcus agalactiae isolated from Nile tilapia (Oreochromis niloticus). Egypt Vet Med Soc Parasitol J 11(8):67–75. https://doi.org/10.21608/evmspj.2015.37946

    Article  Google Scholar 

  • Abutbul S, Golan-Goldhirsh A, Barazani O, Zilberg D (2004) Use of Rosmarinus officinalis as a treatment against Streptococcus iniae in tilapia (Oreochromis sp.). Aquaculture 238(1):97–105. https://doi.org/10.1016/j.aquaculture.2004.05.016

    Article  Google Scholar 

  • Acar Ü, Kesbiç OS, Yılmaz S, Gültepe N, Türker A (2015) Evaluation of the effects of essential oil extracted from sweet orange peel (Citrus sinensis) on growth rate of tilapia (Oreochromis mossambicus) and possible disease resistance against Streptococcus iniae. Aquaculture 437:282–286. https://doi.org/10.1016/j.aquaculture.2014.12.015

    Article  CAS  Google Scholar 

  • Adel M, Pourgholam R, Zorriehzahra J, Ghiasi M (2016) Hemato – immunological and biochemical parameters, skin antibacterial activity, and survival in rainbow trout (Oncorhynchus mykiss) following the diet supplemented with Mentha piperita against Yersinia ruckeri. Fish Shellfish Immunol 55:267–273. https://doi.org/10.1016/j.fsi.2016.05.040

    Article  CAS  PubMed  Google Scholar 

  • Adeniyi O, Olaifa F, Emikpe B, Ogunbanwo S (2021) Effects of dietary tamarind (Tamarindus indica L.) leaves extract on growth performance, nutrient utilization, gut physiology, and susceptibility to Aeromonas hydrophila infection in Nile tilapia (Oreochromis niloticus L.). Int Aquat Res 13(1). https://doi.org/10.22034/iar.2021.1916077.1115

  • Adeoye AA, Yomla R, Jaramillo-Torres A, Rodiles A, Merrifield DL, Davies SJ (2016) Combined effects of exogenous enzymes and probiotic on Nile tilapia (Oreochromis niloticus) growth, intestinal morphology and microbiome. Aquaculture 463:61–70

    Article  CAS  Google Scholar 

  • Adeshina I, Jenyo-Oni A, Emikpe BO, Ajani EK, Abdel-Tawwab M (2019) Stimulatory effect of dietary clove, Eugenia caryophyllata, bud extract on growth performance, nutrient utilization, antioxidant capacity, and tolerance of African catfish, Clarias gariepinus (B.), to Aeromonas hydrophila infection. World Aquac Soc 50:390–405. https://doi.org/10.1111/jwas.12565

    Article  CAS  Google Scholar 

  • Adeshina I, Abdel-Tawwab M, Tijjani ZA, Tiamiyu LO, Jahanbakhshi A (2021a) Dietary Tridax procumbens leaves extract stimulated growth, antioxidants, immunity, and resistance of Nile tilapia, Oreochromis niloticus, to monogenean parasitic infection. Aquaculture 532:736047. https://doi.org/10.1016/j.aquaculture.2020.736047

    Article  CAS  Google Scholar 

  • Adeshina I, Tiamiyu LO, Akpoilih BU, Jenyo-Oni A, Ajani EK (2021b) Dietary Mitracarpus scaber leaves extract improved growth, antioxidants, non-specific immunity, and resistance of Nile tilapia, Oreochromis niloticus to Gyrodactylus malalai infestation. Aquaculture 535:736377. https://doi.org/10.1016/j.aquaculture.2021.736377

    Article  CAS  Google Scholar 

  • Adesuyi AO, Awosanya OA, Adaramola FB, Omeonu AI (2012) Nutritional and phytochemical screening of Aloe barbadensis. Curr Res J Biol Sci 4(1):4–9

    CAS  Google Scholar 

  • Adewolu MA (2008) Potentials of sweet potato (Ipomoea batatas) leaf meal as dietary ingredient for Tilapia zilli fingerlings. Pak J Nutr 7(3):444–449

    Article  CAS  Google Scholar 

  • Afuang W, Siddhuraju P, Becker K (2003) Comparative nutritional evaluation of raw, methanol extracted residues and methanol extracts of moringa (Moringa oleifera Lam.) leaves on growth performance and feed utilization in Nile tilapia (Oreochromis niloticus L.). Aquac Res 34(13):1147–1159

    Article  CAS  Google Scholar 

  • Ali H, Rico A, Murshed-e-Jahan K, Belton B (2016) An assessment of chemical and biological product use in aquaculture in Bangladesh. Aquaculture 454:199–209

    Article  CAS  Google Scholar 

  • Amal MNA, Koh CB, Nurliyana M, Suhaiba M, Nor-Amalina Z, Santha S, Diyana-Nadhirah KP, Yusof MT, Ina-Salwany MY, Zamri-Saad M (2018) A case of natural co-infection of Tilapia Lake Virus and Aeromonas veronii in a Malaysian red hybrid tilapia (Oreochromis niloticus×O. mossambicus) farm experiencing high mortality. Aquaculture 485:12–16. https://doi.org/10.1016/j.aquaculture.2017.11.019

    Article  Google Scholar 

  • Awad E, Awaad A (2017) Role of medicinal plants on growth performance and immune status in fish. Fish Shellfish Immunol 67:40–54. https://doi.org/10.1016/j.fsi.2017.05.034

    Article  CAS  PubMed  Google Scholar 

  • Aydın B, Barbas LAL (2020) Sedative and anesthetic properties of essential oils and their active compounds in fish: a review. Aquaculture 520:734999. https://doi.org/10.1016/j.aquaculture.2020.734999

    Article  CAS  Google Scholar 

  • Azad IS, Al-Yaqout A, Al-Roumi M (2014) Antibacterial and immunity enhancement properties of anaesthetic doses of thyme (Thymus vulgaris) oil and three other anaesthetics in Sparidentax hasta and Acanthopagrus latus. J King Saud Univ Sci 26:101–106. https://doi.org/10.1016/j.jksus.2013.12.003

    Article  Google Scholar 

  • Baba E, Acar Ü, Öntaş C, Kesbiç OS, Yılmaz S (2016) Evaluation of Citrus limon peels essential oil on growth performance, immune response of Mozambique tilapia Oreochromis mossambicus challenged with Edwardsiella tarda. Aquaculture 465:13–18. https://doi.org/10.1016/j.aquaculture.2016.08.023

    Article  CAS  Google Scholar 

  • Bairagi A, Sarkar Ghosh K, Sen SK, Ray AK (2004) Evaluation of the nutritive value of Leucaena leucocephala leaf meal, inoculated with fish intestinal bacteria Bacillus subtilis and Bacillus circulans in formulated diets for rohu, Labeo rohita (Hamilton) fingerlings. Aquac Res 35(5):436–446

    Article  Google Scholar 

  • Ben Salem H, Saghrouni L, Nefzaoui A (2005) Attempts to deactivate tannins in fodder shrubs with physical and chemical treatments. Anim Feed Sci Technol 122(1–2):109–121

    Article  CAS  Google Scholar 

  • Benovit SC, Gressler LT, de Lima Silva L, de Oliveira Garcia L, Okamoto MH, dos Santos Pedron J, Sampaio LA, Rodrigues RV, Heinzmann BM, Baldisserotto B (2012) Anesthesia and transport of Brazilian flounder, Paralichthys orbignyanus, with essential oils of Aloysia gratissima and Ocimum gratissimum. J World Aquac Soc 43(6):896–900

    Article  Google Scholar 

  • Bianchini AE, Garlet QI, Da Cunha JA, Bandeira Junior G, Brusque ICM, Salbego J, Heinzmann BM, Baldisserotto B (2017) Monoterpenoids (thymol, carvacrol and S-(+)-linalool) with anesthetic activity in silver catfish (Rhamdia quelen): evaluation of acetylcholinesterase and GABAergic activity. Braz J Med Biol Res 50(12):e6346

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Biswas AK, Morita T, Yoshizaki G, Maita M, Takeuchi T (2005) Control of reproduction in Nile tilapia Oreochromis niloticus (L.) by photoperiod manipulation. Aquaculture 243(1):229–239. https://doi.org/10.1016/j.aquaculture.2004.10.008

    Article  Google Scholar 

  • Bodur T, Afonso JM, Montero D, Navarro A (2018) Assessment of effective dose of new herbal anesthetics in two marine aquaculture species: Dicentrarchus labrax and Argyrosomus regius. Aquaculture 482:78–82. https://doi.org/10.1016/j.aquaculture.2017.09.029

    Article  CAS  Google Scholar 

  • Bradbury RB, White DE (1954) Estrogens and related substances in plants. Vitam Horm 12:207–233

    Article  CAS  PubMed  Google Scholar 

  • Brandão FR, Farias CFS, de Melo Souza DC, de Oliveira MIB, de Matos LV, Majolo C, de Oliveira MR, Chaves FCM, de Almeida O’Sullivan FL, Chagas EC (2021) Anesthetic potential of the essential oils of Aloysia triphylla, Lippia sidoides and Mentha piperita for Colossoma macropomum. Aquaculture 534:736275. https://doi.org/10.1016/j.aquaculture.2020.736275

    Article  CAS  Google Scholar 

  • Bulfon C, Volpatti D, Galeotti M (2015) Current research on the use of plant-derived products in farmed fish. Aquac Res 46(3):513–551. https://doi.org/10.1111/are.12238

    Article  Google Scholar 

  • Can E, Kızak V, Can ŞS, Özçiçek E (2019) Anesthetic efficiency of three medicinal plant oils for aquatic species: coriander Coriandrum sativum, linaloe tree Bursera delpechiana, and lavender Lavandula hybrida. J Aquat Anim Health 31(3):266–273

    Article  CAS  PubMed  Google Scholar 

  • Caruso D, Lusiastuti AM, Slembrouck J, Komarudin O, Legendre M (2013) Traditional pharmacopeia in small scale freshwater fish farms in West Java, Indonesia: an ethnoveterinary approach. Aquaculture 416–417:334–345

    Article  Google Scholar 

  • Castro SBR, Leal CAG, Freire FR, Carvalho DA, Oliveira DF, Figueiredo HCP (2008) Antibacterial activity of plant extracts from Brazil against fish pathogenic bacteria. Braz J Microbiol 39(4):756–760

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chen HL, Li DF, Chang BY, Gong LM, Dai JG, Yi GF (2003) Effects of Chinese herbal polysaccharides on the immunity and growth performance of young broilers. Poult Sci 82(3):364–370. https://doi.org/10.1093/ps/82.3.364

    Article  CAS  PubMed  Google Scholar 

  • Chitmanat C, Tongdonmuan K, Nunsong W (2005) The use of crude extracts from traditional medicinal plants to eliminate Trichodina sp. in tilapia (Oreochromis niloticus) fingerlings. Songklanakarin J Sci Technol 27:359–364

    Google Scholar 

  • Chuang P-H, Lee C-W, Chou J-Y, Murugan M, Shieh B-J, Chen H-M (2007) Anti-fungal activity of crude extracts and essential oil of Moringa oleifera Lam. Bioresour Technol 98(1):232–236. https://doi.org/10.1016/j.biortech.2005.11.003

    Article  CAS  PubMed  Google Scholar 

  • Citarasu T (2010) Herbal biomedicines: a new opportunity for aquaculture industry. Aquacult Int 18:403–414. https://doi.org/10.1007/s10499-009-9253-7

    Article  Google Scholar 

  • Coyle SD, Mengel GJ, Tidwell JH, Webster CD (2004) Evaluation of growth, feed utilization, and economics of hybrid tilapia, Oreochromis niloticus x Oreochromis aureus, fed diets containing different protein sources in combination with distillers dried grains with solubles. Aquac Res 35(4):365–370

    Article  Google Scholar 

  • da Costa OTF, Dias LC, Malmann CSY, de Lima Ferreira CA, do Carmo IB, Wischneski AG, de Sousa RL, Cavero BAS, Lameiras JLV, Dos-Santos MC (2019) The effects of stocking density on the hematology, plasma protein profile and immunoglobulin production of juvenile tambaqui (Colossoma macropomum) farmed in Brazil. Aquaculture 499:260–268

    Article  CAS  Google Scholar 

  • Dalsgaard J, Verlhac V, Hjermitslev NH, Ekmann KS, Fischer M, Klausen M, Pedersen PB (2012) Effects of exogenous enzymes on apparent nutrient digestibility in rainbow trout (Oncorhynchus mykiss) fed diets with high inclusion of plant-based protein. Anim Feed Sci Technol 171(2–4):181–191

    Article  CAS  Google Scholar 

  • Davies SJ, McConnell S, Bateson RI (1990) Potential of rapeseed meal as an alternative protein source in complete diets for tilapia (Oreochromis mossambicus Peters). Aquaculture 87(2):145–154

    Article  Google Scholar 

  • de Oliveira Hashimoto GS, Neto FM, Ruiz ML, Acchile M, Chagas EC, Chaves FCM, Martins ML (2016) Essential oils of Lippia sidoides and Mentha piperita against monogenean parasites and their influence on the hematology of Nile tilapia. Aquaculture 450:182–186. https://doi.org/10.1016/j.aquaculture.2015.07.029

    Article  CAS  Google Scholar 

  • de Souza A d SL, Peret AC, Hamoy M, de Souza RAL, Torres MF, Barbas LAL (2019) Propofol and essential oil of Nepeta cataria induce anaesthesia and marked myorelaxation in tambaqui Colossoma macropomum: implications on cardiorespiratory responses. Aquaculture 500:160–169

    Article  Google Scholar 

  • Dügenci SK, Arda N, Candan A (2003) Some medicinal plants as immunostimulant for fish. J Ethnopharmacol 88(1):99–106. https://doi.org/10.1016/S0378-8741(03)00182-X

    Article  PubMed  Google Scholar 

  • El Asely A, Amin A, Abd El-Naby AS, Samir F, El-Ashram A, Dawood MAO (2020) Ziziphus mauritiana supplementation of Nile tilapia (Oreochromis niloticus) diet for improvement of immune response to Aeromonas hydrophila infection. Fish Physiol Biochem 46(4):1561–1575. https://doi.org/10.1007/s10695-020-00812-w

    Article  CAS  PubMed  Google Scholar 

  • El-Barbary M, Mehrim A (2009) Protective effect of antioxidant medicinal herbs, rosemary and parsley, on subacute aflatoxicosis in Oreochromis niloticus. J Fisheries Aquatic Sci 4:178–190. https://doi.org/10.3923/JFAS.2009.178.190

    Article  CAS  Google Scholar 

  • Enami HR (2011) A review of using canola/rapeseed meal in aquaculture feeding. J Fish Aquat Sci 6(1):22

    CAS  Google Scholar 

  • FAO (2020) The state of world fisheries and aquaculture 2020. FAO

    Google Scholar 

  • Fontainhas-Fernandes A, Gomes E, Reis-Henriques MA, Coimbra J (1999) Replacement of fish meal by plant proteins in the diet of Nile tilapia: digestibility and growth performance. Aquac Int 7(1):57–67

    Article  CAS  Google Scholar 

  • Foysal MJ, Alam M, Momtaz F, Chaklader MR, Siddik MAB, Cole A, Fotedar R, Rahman MM (2019) Dietary supplementation of garlic (Allium sativum) modulates gut microbiota and health status of tilapia (Oreochromis niloticus) against Streptococcus iniae infection. Aquac Res 50(8):2107–2116. https://doi.org/10.1111/are.14088

    Article  CAS  Google Scholar 

  • Francis G, Makkar HPS, Becker K (2001) Antinutritional factors present in plant-derived alternate fish feed ingredients and their effects in fish. Aquaculture 199(3):197–227. https://doi.org/10.1016/S0044-8486(01)00526-9

    Article  CAS  Google Scholar 

  • Gabriel NN (2019) Review on the progress in the role of herbal extracts in tilapia culture. Cogent Food Agric 5:1619651. https://doi.org/10.1080/23311932.2019.1619651

    Article  CAS  Google Scholar 

  • Gabriel NN, Qiang J, He J, Ma XY, Kpundeh MD, Xu P (2015a) Dietary Aloe vera supplementation on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT). Fish Shellfish Immunol 44(2):504–514. https://doi.org/10.1016/j.fsi.2015.03.002

    Article  CAS  PubMed  Google Scholar 

  • Gabriel NN, Qiang J, Kpundeh MD, Xu P (2015b) Use of herbal extracts for controlling reproduction in tilapia culture: trends and prospects - a review. Isr J Aquac - Bamidgeh 67:23

    Google Scholar 

  • Gabriel NN, Qiang J, Ma XY, He J, Xu P, Omoregie E (2017) Sex-reversal effect of dietary Aloe vera (Liliaceae) on genetically improved farmed Nile Tilapia fry. North Am J Aquac 79(1):100–105. https://doi.org/10.1080/15222055.2016.1236046

    Article  Google Scholar 

  • Gabriel NN, Wilhelm MR, Habte-Tsion H-M, Chimwamurombe P, Omoregie E (2019a) Dietary garlic (Allium sativum) crude polysaccharides supplementation on growth, haematological parameters, whole body composition and survival at low water pH challenge in African catfish (Clarias gariepinus) juveniles. Sci Afr 5:e00128. https://doi.org/10.1016/j.sciaf.2019.e00128

    Article  Google Scholar 

  • Gabriel NN, Wilhelm MR, Habte-Tsion H-M, Chimwamurombe P, Omoregie E, Iipinge LN, Shimooshili K (2019b) Effect of dietary Aloe vera polysaccharides supplementation on growth performance, feed utilization, hemato-biochemical parameters, and survival at low pH in African catfish (Clarias gariepinus) fingerlings. Int Aquat Res 11(1):57–72. https://doi.org/10.1007/s40071-019-0219-8

    Article  Google Scholar 

  • Gabriel NN, Wilhelm MR, Habte-Tsion H-M, Chimwamurombe P, Omoregie E (2021) The effects of dietary garlic (Allium sativum) and Aloe vera crude extract mixtures supplementation on growth performance, feed utilization, hematological parameters, whole body composition, and survival at low pH in African catfish (Clarias gariepinus) juveniles. Sci Afr 11:e00671. https://doi.org/10.1016/j.sciaf.2020.e00671

    Article  Google Scholar 

  • Ghosal I, Mukherjee D, Chakraborty SB (2021) The effects of four plant extracts on growth, sex reversal, immunological and haemato-biochemical parameters in Nile tilapia, Oreochmomis niloticus (Linnaeus, 1758). Aquac Res 52(2):559–576. https://doi.org/10.1111/are.14914

    Article  CAS  Google Scholar 

  • Gilderhus PA, Marking LL (1987) Comparative efficacy of 16 anesthetic chemicals on rainbow trout. North Am J Fish Manag 7(2):288–292

    Article  Google Scholar 

  • Gressler LT, Riffel APK, Parodi TV, Saccol EMH, Koakoski G, da Costa ST, Pavanato MA, Heinzmann BM, Caron B, Schmidt D (2014) Silver catfish Rhamdia quelen immersion anaesthesia with essential oil of Aloysia triphylla (L’Hérit) Britton or tricaine methanesulfonate: effect on stress response and antioxidant status. Aquac Res 45(6):1061–1072

    Article  CAS  Google Scholar 

  • Gurkan M, Yi̇lmaz S, Kaya H, Ergun S, Alkan S (2015) Influence of three spice powders on the survival and histopathology of Oreochromis mossambicus before and after Streptococcus iniae infection. Mar Sci Technol Bull 4(1):1–5

    Google Scholar 

  • Harikrishnan R, Balasundaram C, Bhuvaneswari R (2005) Restorative effect of Azadirachta indica aqueous leaf extract dip treatment on haematological parameter changes in Cyprinus carpio (L.) experimentally infected with Aphanomyces invadans fungus. J Appl Ichthyol 21(5):410–413. https://doi.org/10.1111/j.1439-0426.2005.00614.x

    Article  Google Scholar 

  • Harikrishnan R, Balasundaram C, Heo M-S (2009) Effect of chemotherapy, vaccines and immunostimulants on innate immunity of goldfish infected with Aeromonas hydrophila. Dis Aquat Org 88(1):45–54. https://doi.org/10.3354/dao02143

    Article  CAS  Google Scholar 

  • Harikrishnan R, Balasundaram C, Heo M-S (2011) Impact of plant products on innate and adaptive immune system of cultured finfish and shellfish. Aquaculture 317(1):1–15. https://doi.org/10.1016/j.aquaculture.2011.03.039

    Article  CAS  Google Scholar 

  • Heuer OE, Kruse H, Grave K, Collignon P, Karunasagar I, Angulo FJ (2009) Human health consequences of use of antimicrobial agents in aquaculture. Clin Infect Dis 49(8):1248–1253. https://doi.org/10.1086/605667

    Article  PubMed  Google Scholar 

  • Hlophe SN (2015) Utilization of Moringa oleifera (moringa) and Pennisetum clandestunum (kikuyu) leaf meals by three commonly cultured fish species in South Africa: Tilapia rendalli, Oreochromis mossambicus and Clarias gariepinus. Univ Limpopo:235

    Google Scholar 

  • Hlophe SN, Moyo NAG (2014) A comparative study on the use of Pennisetum clandestinum and Moringa oleifera as protein sources in the diet of the herbivorous Tilapia rendalli. Aquac Int 22:1245–1262

    Article  CAS  Google Scholar 

  • Hlophe-Ginindza SN, Moyo NA, Ngambi JW, Ncube I (2016) The effect of exogenous enzyme supplementation on growth performance and digestive enzyme activities in O reochromis mossambicus fed kikuyu-based diets. Aquac Res 47(12):3777–3787

    Article  CAS  Google Scholar 

  • Hoseini SM, Taheri Mirghaed A, Yousefi M (2019) Application of herbal anaesthetics in aquaculture. Rev Aquac 11(3):550–564. https://doi.org/10.1111/raq.12245

    Article  Google Scholar 

  • Huchzermeyer KDA, van der Waal BCW (2012) Epizootic ulcerative syndrome: exotic fish disease threatens Africa’s aquatic ecosystems. J S Afr Vet Assoc 83(1):39–46

    Article  Google Scholar 

  • Immanuel G, Uma RP, Iyapparaj P, Citarasu T, Peter SMP, Babu MM, Palavesam A (2009) Dietary medicinal plant extracts improve growth, immune activity and survival of tilapia Oreochromis mossambicus. J Fish Biol 74(7):1462–1475. https://doi.org/10.1111/j.1095-8649.2009.02212.x

    Article  CAS  PubMed  Google Scholar 

  • Iwu MM (2014) Handbook of African medicinal plants. Routledge CRC Press. https://www.routledge.com/Handbook-of-African-Medicinal-Plants/Iwu/p/book/9781466571976. Accessed 27 Apr 2021

  • Jegede T (2010) Control of reproduction in Oreochromis niloticus (Linnaeus 1758) using Hibiscus Rosa-sinensis (Linn.) leaf meal as reproduction inhibitor. J Agric Sci 2(4):149. https://doi.org/10.5539/jas.v2n4p149

    Article  Google Scholar 

  • Ji SC, Jeong GS, Im GS, Lee SW, Yoo JH, Takii K (2007) Dietary medicinal herbs improve growth performance, fatty acid utilization, and stress recovery of Japanese flounder. Fish Sci 73(1):70–76. https://doi.org/10.1111/j.1444-2906.2007.01303.x

    Article  CAS  Google Scholar 

  • Khumpirapang N, Chaichit S, Jiranusornkul S, Pikulkaew S, Müllertz A, Okonogi S (2018) In vivo anesthetic effect and mechanism of action of active compounds from Alpinia galanga oil on Cyprinus carpio (koi carp). Aquaculture 496:176–184. https://doi.org/10.1016/j.aquaculture.2018.07.017

    Article  CAS  Google Scholar 

  • Kibenge FS (2019) Emerging viruses in aquaculture. Curr Opin Virol 34:97–103. https://doi.org/10.1016/j.coviro.2018.12.008

    Article  PubMed  Google Scholar 

  • Krogdahl A, Bakke-McKellep AM, Roed KH, Baeverfjord G (2000) Feeding Atlantic salmon Salmo salar L. soybean products: effects on disease resistance (furunculosis), and lysozyme and IgM levels in the intestinal mucosa. Aquac Nutr 6(2):77–84

    Article  Google Scholar 

  • Kuete V (2013) Medicinal plant research in Africa: pharmacology and chemistry. Newnes

    Google Scholar 

  • Kumar G, Engle CR (2016) Technological advances that led to growth of shrimp, Salmon, and tilapia farming. Rev Fish Sci Aquac 24(2):136–152. https://doi.org/10.1080/23308249.2015.1112357

    Article  Google Scholar 

  • Lin S, Mai K, Tan B (2007) Effects of exogenous enzyme supplementation in diets on growth and feed utilization in tilapia, Oreochromis niloticus x O. aureus. Aquac Res 38(15):1645–1653

    Article  CAS  Google Scholar 

  • Liu Q, Hou Z, Wen H, Li J, He F, Wang J, Guan B, Wang Q (2016) Effect of stocking density on water quality and (Growth, Body Composition and Plasma Cortisol Content) performance of pen-reared rainbow trout (Oncorhynchus mykiss). J Ocean Univ China 15(4):667–675. https://doi.org/10.1007/s11802-016-2956-2

    Article  CAS  Google Scholar 

  • Makkar HPS (2003) Effects and fate of tannins in ruminant animals, adaptation to tannins, and strategies to overcome detrimental effects of feeding tannin-rich feeds. Small Rumin Res 49(3):241–256

    Article  Google Scholar 

  • Makkar HP, Blümmel M, Borowy NK, Becker K (1993) Gravimetric determination of tannins and their correlations with chemical and protein precipitation methods. J Sci Food Agric 61(2):161–165

    Article  CAS  Google Scholar 

  • Makkar HPS, Francis G, Becker K (2007) Bioactivity of phytochemicals in some lesser-known plants and their effects and potential applications in livestock and aquaculture production systems. Animal 1(9):1371–1391

    Article  CAS  PubMed  Google Scholar 

  • Marrufo T, Nazzaro F, Mancini E, Fratianni F, Coppola R, De Martino L, Agostinho AB, De Feo V (2013) Chemical composition and biological activity of the essential oil from leaves of Moringa oleifera Lam. cultivated in Mozambique. Molecules 18(9):10989–11000. https://doi.org/10.3390/molecules180910989

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Mbokane EM, Moyo NAG (2018a) A preliminary investigation into the potential effect of Artemisia afra on growth and disease resistance in sub-adults of Oreochromis mossambicus. Aquaculture 482:197–202

    Article  CAS  Google Scholar 

  • Mbokane EM, Moyo NAG (2018b) Alterations of haemato-biochemical parameters pre and post-challenge with Aeromonas hydrophila and survival of Oreochromis mossambicus fed Moringa oleifera-based diets. Fish Shellfish Immunol 83:213–222. https://doi.org/10.1016/j.fsi.2018.09.017

    Article  PubMed  Google Scholar 

  • Mbokane E, Moyo N (2020a) Effect of dietary Artemisia afra on growth, some innate immunological parameters in Clarias gariepinus challenged with Aeromonas hydrophila. Aquac Int 28:539–553. https://doi.org/10.1007/s10499-019-00479-y

    Article  CAS  Google Scholar 

  • Mbokane EM, Moyo NAG (2020b) Effects of dietary levels of essential oil extracts from Moringa oleifera and Artemisia afra on kidney histology, haemato-immunological parameters and disease resistance in Clarias gariepinus. Aquac Res 51(1):410–425. https://doi.org/10.1111/are.14388

    Article  CAS  Google Scholar 

  • Mirghaed AT, Ghelichpour M, Hoseini SM (2016) Myrcene and linalool as new anesthetic and sedative agents in common carp, Cyprinus carpio-Comparison with eugenol. Aquaculture 464:165–170

    Article  Google Scholar 

  • Mirghaed AT, Yasari M, Mirzargar SS, Hoseini SM (2018) Rainbow trout (Oncorhynchus mykiss) anesthesia with myrcene: efficacy and physiological responses in comparison with eugenol. Fish Physiol Biochem 44(3):919–926

    Article  CAS  PubMed  Google Scholar 

  • Montero D, Izquierdo MS, Tort L, Robaina L, Vergara JM (1999) High stocking density produces crowding stress altering some physiological and biochemical parameters in gilthead seabream, Sparus aurata, juveniles. Fish Physiol Biochem 20(1):53–60. https://doi.org/10.1023/A:1007719928905

    Article  CAS  Google Scholar 

  • Moustafa EM, Dawood MAO, Assar DH, Omar AA, Elbialy ZI, Farrag FA, Shukry M, Zayed MM (2020) Modulatory effects of fenugreek seeds powder on the histopathology, oxidative status, and immune related gene expression in Nile tilapia (Oreochromis niloticus) infected with Aeromonas hydrophila. Aquaculture 515:734589. https://doi.org/10.1016/j.aquaculture.2019.734589

    Article  CAS  Google Scholar 

  • Mukhopadhyay N, Ray AK (1999) Effect of fermentation on the nutritive value of sesame seed meal in the diets for rohu, Labeo rohita (Hamilton), fingerlings. Aquac Nutr 5:229–236

    Article  Google Scholar 

  • Musuka CG, Likongwe JS, Kang’Ombe J, Jere WWL, Mtethiwa AH (2009) The effect of dietary protein and water temperatures on performance of Tilapia rendalli juveniles reared in indoor tanks. Pak J Nutr 8(10):1526–1531

    Article  CAS  Google Scholar 

  • Naiel MAE, Ismael NEM, Negm SS, Ayyat MS, Al-Sagheer AA (2020) Diseases in Nile Tilapia (Oreochromis niloticus). Aquaculture 526:8

    Google Scholar 

  • Ndong D, Fall J (2011) The effect of garlic (Allium sativum) on growth and immune responses of hybrid tilapia (Oreochromis niloticus x Oreochromis aureus). J Clin Immnunol Immunopathol Res 3(1):1–9

    Google Scholar 

  • Ng WK, Wee KL (1989) The nutritive value of cassava leaf meal in pelleted feed for Nile tilapia. Aquaculture 83(1–2):45–58

    Article  Google Scholar 

  • Ngugi CC, Oyoo-Okoth E, Muchiri M (2017) Effects of dietary levels of essential oil (EO) extract from bitter lemon (Citrus limon) fruit peels on growth, biochemical, haemato-immunological parameters, and disease resistance in Juvenile Labeo victorianus fingerlings challenged with Aeromonas hydrophila. Aquac Res 48(5):2253–2265. https://doi.org/10.1111/are.13062

    Article  CAS  Google Scholar 

  • Nya EJ, Austin B (2009) Use of garlic, Allium sativum, to control Aeromonas hydrophila infection in rainbow trout, Oncorhynchus mykiss (Walbaum). J Fish Dis 32(11):963–970. https://doi.org/10.1111/j.1365-2761.2009.01100.x

    Article  CAS  PubMed  Google Scholar 

  • Nyadjeu P, Angoun J, Ndasi NP, Tabi-Tomedi ME (2019) Effect of Garcinia kola seeds supplemented diet on growth performance and gonadal development of Oreochromis niloticus juveniles breed in ponds. Fish Aquat Sci 22(1):20. https://doi.org/10.1186/s41240-019-0136-1

    Article  CAS  Google Scholar 

  • Obaro IO, Nzeh CG, Oguntoye SO (2012) Control of reproduction in Oreochromis niloticus (L) using crude extract of Azadirachta indica saponin. Adv Environ Biol 6:1353–1356

    Google Scholar 

  • Omitoyin BO, Ajani EK, Orisasona O, Bassey HE, Kareem KO, Osho FE (2019) Effect of guava Psidium guajava (L.) aqueous extract diet on growth performance, intestinal morphology, immune response and survival of Oreochromis niloticus challenged with Aeromonas hydrophila. Aquac Res 50(7):1851–1861. https://doi.org/10.1111/are.14068

    Article  CAS  Google Scholar 

  • Parodi TV, Cunha MA, Heldwein CG, de Souza DM, Martins ÁC, de O Garcia L, Junior WW, Monserrat JM, Schmidt D, Caron BO (2012) The anesthetic efficacy of eugenol and the essential oils of Lippia alba and Aloysia triphylla in post-larvae and sub-adults of Litopenaeus vannamei (Crustacea, Penaeidae). Comp Biochem Physiol Part C Toxicol Pharmacol 155(3):462–468

    Article  CAS  Google Scholar 

  • Pu H, Li X, Du Q, Cui H, Xu Y (2017) Research progress in the application of Chinese herbal medicines in aquaculture: a review. Engineering 3(5):731–737. https://doi.org/10.1016/J.ENG.2017.03.017

    Article  Google Scholar 

  • Ravikumar S, Gracelin N, Anitha Anandha G, Selvan Palani AK (2011) In vitro antibacterial activity of coastal medicinal plants against isolated bacterial fish pathogens. Int J Pharma Res Devel 3(4):109–116

    Google Scholar 

  • Reverter M, Bontemps N, Lecchini D, Banaigs B, Sasal P (2014) Use of plant extracts in fish aquaculture as an alternative to chemotherapy: current status and future perspectives. Aquaculture 433:50–61. https://doi.org/10.1016/j.aquaculture.2014.05.048

    Article  Google Scholar 

  • Reverter M, Tapissier-Bontemps N, Sasal P, Saulnier D (2017) Use of medicinal plants in aquaculture. In: Austin B, Newaj-Fyzul A (eds) Diagnosis and control of diseases of fish and shellfish. Wiley, Chichester, pp 223–261

    Chapter  Google Scholar 

  • Reyes-Becerril M, Angulo C, Silva-Jara J (2021) Antibacterial and immunomodulatory activity of moringa (Moringa oleifera) seed extract in Longfin yellowtail (Seriola rivoliana) peripheral blood leukocytes. Aquac Res 00:1–10. https://doi.org/10.1111/are.15245

    Article  CAS  Google Scholar 

  • Richter N, Siddhuraju P, Becker K (2003) Evaluation of nutritional quality of moringa (Moringa oleifera Lam.) leaves as an alternative protein source for Nile tilapia (Oreochromis niloticus L.). Aquaculture 217(1–4):599–611

    Article  Google Scholar 

  • Sakai M (1999) Current research status of fish immunostimulants. Aquaculture 172(1):63–92. https://doi.org/10.1016/S0044-8486(98)00436-0

    Article  CAS  Google Scholar 

  • Shangliang T, Hetrick FM, Roberson BS, Baya A (1990) The antibacterial and antiviral activity of herbal extracts for fish pathogens. J Ocean Univ Qingdao. https://en.cnki.com.cn/Article_en/CJFDTotal-QDHY199002006.htm. Accessed 13 May 2021

  • Shiau S-Y, Lin S-F, Yu S-L, Lin A-L, Kwok C-C (1990) Defatted and full-fat soybean meal as partial replacements for fishmeal in tilapia (Oreochromis niloticus x O. aureus) diets at low protein level. Aquaculture 86(4):401–407

    Article  Google Scholar 

  • Siwicki AK, Anderson DP, Rumsey GL (1994) Dietary intake of immunostimulants by rainbow trout affects non-specific immunity and protection against furunculosis. Vet Immunol Immunopathol 41(1):125–139. https://doi.org/10.1016/0165-2427(94)90062-0

    Article  CAS  PubMed  Google Scholar 

  • Sohn KS, Kim MK, Kim JD, Han IK (2000) The role of immunostimulants in monogastric animal and fish - review. Asian-Australas J Anim Sci 13(8):1178–1187

    Article  CAS  Google Scholar 

  • Soltan MA (2009) Effect of dietary fish meal replacement by poultry by-product meal with different grain source and enzyme supplementation on performance, feces recovery, body composition and nutrient balance of Nile tilapia. Pak J Nutr 8(4):395–407

    Article  CAS  Google Scholar 

  • Tahir M, Saleh F, Ohtsuka A, Hayashi K (2008) An effective combination of carbohydrases that enables reduction of dietary protein in broilers: importance of hemicellulase. Poult Sci 87(4):713–718

    Article  CAS  PubMed  Google Scholar 

  • Toni C, Becker AG, Simões LN, Pinheiro CG, de Lima Silva L, Heinzmann BM, Caron BO, Baldisserotto B (2014) Fish anesthesia: effects of the essential oils of Hesperozygis ringens and Lippia alba on the biochemistry and physiology of silver catfish (Rhamdia quelen). Fish Physiol Biochem 40(3):701–714

    CAS  PubMed  Google Scholar 

  • Turan F, Çek Ş (2007) Masculinization of African catfish (Clarias gariepinus) treated with gokshura (Tribulus terrestris). Isr J Aquac - Bamidgeh 59:224–229. https://doi.org/10.46989/001c.20528

    Article  Google Scholar 

  • Turan F, Akyurt I, Cek-Yalniz S (2021) Effect of red clover extract on sex reversal and gonadal development in the African catfish, Clarias gariepinus (Burchell, 1822). Pak J Zool:1–7. https://doi.org/10.17582/JOURNAL.PJZ/20190211080201

  • Turker H, Yildirim AB, Karakaş FP (2009) Sensitivity of bacteria isolated from fish to some medicinal plants. Turk J Fish Aquat Sci 9(2):181–186

    Article  Google Scholar 

  • Van Hai N (2015) The use of medicinal plants as immunostimulants in aquaculture: a review. Aquaculture 446:88–96. https://doi.org/10.1016/j.aquaculture.2015.03.014

    Article  CAS  Google Scholar 

  • Webster CD, Tidwell JH, Goodgame LS, Yancey DH, Mackey L (1992) Use of soybean meal and distillers grains with solubles as partial or total replacement of fish meal in diets for channel catfish, Ictalurus punctatus. Aquaculture 106(3–4):301–309

    Article  Google Scholar 

  • Wee KL, Shu S-W (1989) The nutritive value of boiled full-fat soybean in pelleted feed for Nile tilapia. Aquaculture 81(3–4):303–314

    Article  Google Scholar 

  • Whyte SK (2007) The innate immune response of finfish – a review of current knowledge. Fish Shellfish Immunol 23(6):1127–1151. https://doi.org/10.1016/j.fsi.2007.06.005

    Article  CAS  PubMed  Google Scholar 

  • Wu Z, Fisher RJ, Polan CE, Schwab CG (1997) Lactational performance of cows fed low or high ruminally undegradable protein prepartum and supplemental methionine and lysine postpartum. J Dairy Sci 80(4):722–729

    Article  CAS  PubMed  Google Scholar 

  • Xie B (2013) Organic aquaculture in China: a review from a global perspective. Aquaculture 414–415:243–253

    Article  Google Scholar 

  • Xie J, Liu B, Zhou Q, Su Y, He Y, Pan L, Ge X, Xu P (2008) Effects of anthraquinone extract from rhubarb Rheum officinale Bail on the crowding stress response and growth of common carp Cyprinus carpio var. Jian Aquaculture 281(1):5–11. https://doi.org/10.1016/j.aquaculture.2008.03.038

    Article  CAS  Google Scholar 

  • Yildiz HY, Van QP, Parisi G, Sao MD (2019) Anti-parasitic activity of garlic (Allium sativum) and onion (Allium cepa) juice against crustacean parasite, Lernantropus kroyeri, found on European sea bass (Dicentrarchus labrax). Ital J Anim Sci 18(1):833–837. https://doi.org/10.1080/1828051X.2019.1593058

    Article  Google Scholar 

  • Yilmaz S (2019) Effects of dietary blackberry syrup supplement on growth performance, antioxidant, and immunological responses, and resistance of Nile tilapia, Oreochromis niloticus to Plesiomonas shigelloides. Fish Shellfish Immunol 84:1125–1133. https://doi.org/10.1016/j.fsi.2018.11.012

    Article  CAS  PubMed  Google Scholar 

  • Yousif OM, Alhadrami GA, Pessarakli M (1994) Evaluation of dehydrated alfalfa and salt bush (Atriplex) leaves in diets for tilapia (Oreochromis aureus L.). Aquaculture 126(3–4):341–347

    Article  Google Scholar 

  • Yu Y, Shen M, Song Q, Xie J (2018) Biological activities and pharmaceutical applications of polysaccharide from natural resources: a review. Carbohydr Polym 183:91–101. https://doi.org/10.1016/j.carbpol.2017.12.009

    Article  CAS  PubMed  Google Scholar 

  • Zahl IH, Samuelsen O, Kiessling A (2012) Anaesthesia of farmed fish: implications for welfare. Fish Physiol Biochem 38(1):201–218

    Article  CAS  PubMed  Google Scholar 

  • Zahran E, Risha E, Abdel Hamid F, Mahgoub HA, Ibrahim T (2014) Effects of dietary Astragalus polysaccharides (APS) on growth performance, immunological parameters, digestive enzymes, and intestinal morphology of Nile tilapia (Oreochromis niloticus). Fish Shellfish Immunol 38:149–157. https://doi.org/10.1016/j.fsi.2014.03.002

    Article  CAS  PubMed  Google Scholar 

  • Zahran E, El-Gawad EAA, Risha E (2018) Dietary Withania sominefera root confers protective and immunotherapeutic effects against Aeromonas hydrophila infection in Nile tilapia (Oreochromis niloticus). Fish Shellfish Immunol 80:641–650

    Article  CAS  PubMed  Google Scholar 

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Gabriel, N.N. et al. (2022). Medicinal Plants: A Perspective on Their Application in the African Smallholder Aquaculture Farms. In: Mupambwa, H.A., Nciizah, A.D., Nyambo, P., Muchara, B., Gabriel, N.N. (eds) Food Security for African Smallholder Farmers. Sustainability Sciences in Asia and Africa(). Springer, Singapore. https://doi.org/10.1007/978-981-16-6771-8_12

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