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Recent Advances in Stem Cells for Dental Tissue Engineering

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Engineering Materials for Stem Cell Regeneration

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Abstract

Stem cell therapy has been signified as an important field of dentistry, regenerative medicine, and tissue engineering research since the uncovering and design of mesenchymal stem cells (MSCs). MSCs, which can be obtained from various sources, may accomplish a vital role in tissue/organ growth and repair and have immense potentials in bone and dental tissue regeneration. General dental therapies involve the use of specialized tissue-adapted materials that are still uncertain in terms of their effectiveness and durability. Efforts of the past few decades have focused on novel therapeutic approaches for tooth regeneration wholly or partially, which has employed sophisticated biomaterials and implants. Current dental treatments have focused on multidisciplinary approaches by combining advanced tissue engineering, biomaterials, scaffolds, digital technology, and stem cells, which have exhibited great potentials. Therapeutic approaches based on stem cells would be alternative treatments in dentistry since they are highly promising in physiologically advanced structural and functional outcomes. To take a look at future dentistry in terms of stem cell-based treatment, the objective of this chapter is to introduce the history of stem cells, various types of stem cells related to dentistry, their characteristics, differentiation, isolation, collection, and preservation. This chapter outlines strategies of stem cell therapy applied in various dental/tooth/orofacial organ and tissue regeneration to provide a theoretical basis for clinical workflow. Further, the current status of dental and medical applications is within the scope of this chapter.

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Authors and Affiliations

  1. Research Core for Interdisciplinary Sciences, Okayama University, Okayama, Japan

    Mohammed Zahedul Islam Nizami & Yuta Nishina

  2. Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan

    Yuta Nishina

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  1. Mohammed Zahedul Islam Nizami
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  2. Yuta Nishina
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Correspondence to Yuta Nishina .

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  1. Department of Nanotechnology, School of Biological Sciences, University of Kashmir, Srinagar, Jammu and Kashmir, India

    Faheem A. Sheikh

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Nizami, M.Z.I., Nishina, Y. (2021). Recent Advances in Stem Cells for Dental Tissue Engineering. In: Sheikh, F.A. (eds) Engineering Materials for Stem Cell Regeneration. Springer, Singapore. https://doi.org/10.1007/978-981-16-4420-7_12

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