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Plant Secondary Metabolites for Tackling Antimicrobial Resistance: A Pharmacological Perspective

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Antimicrobial Resistance

Abstract

The practice of using medicinal plants in treating various diseases and ailments dates back to over 60,000 years ago. These medicinal plants produce a diversity of secondary metabolites which are natural sources of biologically active compounds that can be classified into phenolics, alkaloids, saponins, terpenes, glycosides and flavonoids. These active compounds exert significant antimicrobial resistance (AMR) and pharmacological activity. In the current scenario, more attention is being focussed towards plant-based drug discovery in treating diseases, especially in fulfilling therapeutic requirements of dreaded diseases such as cancer, HIV and neurodegenerative diseases. This review aims to elucidate and understand different classifications of plant secondary metabolites towards understanding their mechanisms of action in tackling antimicrobial resistance (AMR) as well as their benefits and usage in pharmacology.

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Acknowledgement

The authors would like to thank the Higher Colleges of Technology, United Arab Emirates, and UCSI University Research Excellence and Innovation Grant (REIG-FAS-2020/032) for the support.

Author information

Authors and Affiliations

  1. School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Subang Jaya, Malaysia

    Sathiya Maran

  2. Perdana University Graduate School of Medicine, Perdana University, Wisma Chase Perdana, Changkat Semantan, Damansara Heights, Kuala Lumpur, Malaysia

    Wendy Wai Yeng Yeo

  3. Health Sciences Division, Abu Dhabi Women’s College, Higher Colleges of Technology, Abu Dhabi, United Arab Emirates

    Swee-Hua Erin Lim & Kok-Song Lai

Authors
  1. Sathiya Maran
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  2. Wendy Wai Yeng Yeo
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  3. Swee-Hua Erin Lim
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  4. Kok-Song Lai
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Corresponding author

Correspondence to Kok-Song Lai .

Editor information

Editors and Affiliations

  1. Department of Biotechnology, Savitribai Phule Pune University, Modern College of Arts, Science and Commerce, Ganeshkhind, Maharashtra, India

    Vinay Kumar

  2. Department of Botany, Savitribai Phule Pune University, Ramkrishna More Arts, Commerce and Science College, Pune, Maharashtra, India

    Varsha Shriram

  3. Department of Pharmacy, Birla Institute of Technology and Science, Pilani, Rajasthan, India

    Atish Paul

  4. School of Biomedical Sciences, Mahatma Gandhi Mission Institute of Heal, Navi Mumbai, Maharashtra, India

    Mansee Thakur

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© 2022 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.

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Maran, S., Yeo, W.W.Y., Lim, SH.E., Lai, KS. (2022). Plant Secondary Metabolites for Tackling Antimicrobial Resistance: A Pharmacological Perspective. In: Kumar, V., Shriram, V., Paul, A., Thakur, M. (eds) Antimicrobial Resistance. Springer, Singapore. https://doi.org/10.1007/978-981-16-3120-7_6

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