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Coscinium fenestratum: A Review on Phytochemicals and Pharmacological Properties

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Natural Bio-active Compounds

Abstract

Coscinium fenestratum has been used in the traditional medicine, especially in the Ayurvedic method of healing as this plant can be found vastly in the Western Ghats of India. The distribution of this plant is concentrated to the Southeast Asia including Sri Lanka, India, Cambodia, Vietnam, Peninsular Malaysia, Sumatra, West Java, Borneo, Northeast of Thailand and Laos. This review is related to the phytochemicals and pharmacological effects of C. fenestratum. The major chemical constituents present in this plant include alkaloids, flavonoids and steroids. The most important bio-active compound is the berberine, which is the most widely studied plant compound. This plant exerts several pharmacological effects including antidiabetic, anticancer, antibacterial, antimalarial, antioxidant, antihypertensive, antiulcer, neuroprotector and wound healing activities. This chapter is supported by in vitro and in vivo studies carried out from the year of 1970 to 2016, which are available from PubMed, ScienceDirect, Google Scholar and Scopus.

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Acknowledgments

The authors are thankful to the International Islamic University Malaysia for funding through grant no RIGS15-095-0095 and P-RIGS18-028-0028.

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Authors and Affiliations

  1. Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia

    Muhammad Taher, Mohamad Shahreen Amri & Muhammad Badri Abdul Kudos

  2. Department of Chemistry, Faculty of Science, International Islamic University Malaysia, Kuantan, Pahang, Malaysia

    Deny Susanti, Anis Natasha Shafawi & Soraya Nur Yazid

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  1. Muhammad Taher
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  2. Mohamad Shahreen Amri
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  3. Deny Susanti
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  4. Muhammad Badri Abdul Kudos
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  6. Soraya Nur Yazid
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Correspondence to Muhammad Taher .

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Editors and Affiliations

  1. Department of Biotechnology, East West First Grade College of Science, Bengaluru, Karnataka, India

    Mallappa Kumara Swamy

  2. Department of Botany, Gandhi Faiz-e-Aam College, Shahjahanpur, Uttar Pradesh, India

    Mohd Sayeed Akhtar

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Taher, M., Amri, M.S., Susanti, D., Abdul Kudos, M.B., Shafawi, A.N., Yazid, S.N. (2019). Coscinium fenestratum: A Review on Phytochemicals and Pharmacological Properties. In: Swamy, M., Akhtar, M. (eds) Natural Bio-active Compounds. Springer, Singapore. https://doi.org/10.1007/978-981-13-7205-6_5

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