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MRI-Ultrasound Fusion Prostate Biopsy

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Abstract

MRI prostate has emerged as the most accurate imaging available for detection of significant prostate cancer. Standardized reporting using the The Prostate Imaging Reporting and Data System (PI-RADS) system for MRI prostate is important for clinical management and for professional communication. Besides diagnosis of prostate cancer, MRI prostate also enabled targeted prostate biopsy, and MRI-Ultrasound fusion biopsy has been increasingly utilized for targeting of suspicious MRI lesions during real-time ultrasound scanning of prostate. The elements of a successful MRI-Ultrasound fusion biopsy program include high quality MRI imaging and reporting, and the proper usage of fusion biopsy machines in achieving an accurate targeted biopsy.

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References

  • Abdi H, Zargar H, Goldenberg SL, et al. Multiparametric magnetic resonance imaging-targeted biopsy for the detection of prostate cancer in patients with prior negative biopsy results. Urol Oncol. 2015;33(4):165.e1–7.

    Article  Google Scholar 

  • Ahmed HU, El-Shater Bosaily A, Brown LC, et al. Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study. Lancet. 2017;389(10071):815–22.

    Article  PubMed  Google Scholar 

  • American Urological Association (AUA) and Society of Abdominal Radiology (SAR) Joint Consensus Statement. Prostate MRI and MRI-targeted biopsy in patients with prior negative biopsy. Collaborative initiative of the American Urological Association and the Society of Abdominal Radiology’s Prostate Cancer Disease-Focused Panel. 2016. https://c.ymcdn.com/sites/abdominalradiology.site-ym.com/resource/resmgr/Edu_DFPprostate/AUA-SAR.pdf.

  • Arsov C, Rabenalt R, Blondin D, et al. Prospective randomized trial comparing magnetic resonance imaging (MRI)guided in-bore biopsy to MRI-ultrasound fusion and transrectal ultrasound-guided prostate biopsy in patients with prior negative biopsies. Eur Urol. 2015;68(4):713–20.

    Article  PubMed  Google Scholar 

  • Baco E, Rud E, Eri LM, et al. A randomized controlled trial to assess and compare the outcomes of two-core prostate biopsy guided by fused magnetic resonance and transrectal ultrasound images and traditional 12-core systematic biopsy. Eur Urol. 2016;69:149–56.

    Article  PubMed  Google Scholar 

  • Bansal S, Gupta NP, Yadav R, et al. Multiparametric magnetic resonance imaging-transrectal ultrasound fusion prostate biopsy: a prospective, single centre study. Indian J Urol. 2017;33(2):134–9.

    Article  PubMed  PubMed Central  Google Scholar 

  • Barentsz JO, Richenberg J, Clements R, et al. ESUR prostate MR guidelines 2012. Eur Radiol. 2012;22(4):746–57.

    Article  PubMed  PubMed Central  Google Scholar 

  • Bjurlin MA, Meng X, Le Nobin J, et al. Optimization of prostate biopsy: the role of magnetic resonance imaging targeted biopsy in detection, localization and risk assessment. J Urol. 2014;192(3):648–58.

    Article  PubMed  PubMed Central  Google Scholar 

  • Borkowetz A, Platzek I, Toma M, et al. Comparison of systematic transrectal biopsy to transperineal magnetic resonance imaging/ ultrasound-fusion biopsy for the diagnosis of prostate cancer. BJU Int. 2015;116:873–9.

    Article  PubMed  Google Scholar 

  • Calio B, Sidana A, Sugano D, et al. Changes in prostate cancer detection rate of MRI-TRUS fusion vs systematic biopsy over time: evidence of a learning curve. Prostate Cancer Prostatic Dis. 2017;20(4):436–41.

    Article  CAS  PubMed  Google Scholar 

  • Chen R, Ren S, Chinese Prostate Cancer Consortium, et al. Prostate cancer in Asia: a collaborative report. Asian J Urol. 2014;1(1):15–29.

    Google Scholar 

  • Delongchamps NB, Peyromaure M, Schull A, et al. Prebiopsy magnetic resonance imaging and prostate cancer detection: comparison of random and targeted biopsies. J Urol. 2013;189:493–9.

    Article  PubMed  Google Scholar 

  • Dickinson L, Ahmed HU, Allen C, et al. Magnetic resonance imaging for the detection, localisation, and characterisation of prostate cancer: recommendations from a European consensus meeting. Eur Urol. 2011;59(4):477–94.

    Article  PubMed  Google Scholar 

  • Futterer JJ, Briganti A, De Visschere P, et al. Can clinically significant prostate cancer be detected with multiparametric magnetic resonance imaging? A systematic review of the literature. Eur Urol. 2015;68:1045–53.

    Article  PubMed  Google Scholar 

  • de Gorski A, Roupret M, Peyronnet B, et al. Accuracy of magnetic resonance imaging/ultrasound fusion targeted biopsies to diagnose clinical significant prostate cancer in enlarged compared to smaller prostates. J Urol. 2015;194:669–73.

    Article  PubMed  Google Scholar 

  • Halpern JA, Shoag JE, Artis AS, et al. National trends in prostate biopsy and radical prostatectomy volumes following the US Preventive Services Task Force guidelines against prostate-specific antigen screening. JAMA Surg. 2017;152(2):192–8.

    Article  PubMed  Google Scholar 

  • Hoeks CM, Schouten MG, Bomers JG, et al. Three-Tesla magnetic resonance-guided prostate biopsy in men with increased prostate-specific antigen and repeated, negative, random, systematic, transrectal ultrasound biopsies: detection of clinically significant prostate cancers. Eur Urol. 2012;62(5):902–9.

    Article  PubMed  Google Scholar 

  • Hong CW, Rais-Bahrami S, Walton-Diaz A, et al. Comparison of magnetic resonance imaging and ultrasound (MRI-US) fusion guided prostate biopsies obtained from axial and sagittal approaches. BJU Int. 2015;115(5):772–9.

    Article  PubMed  Google Scholar 

  • Ikonen S, Kivisaari L, Vehmas T, et al. Optimal timing of post-biopsy MR imaging of the prostate. Acta Radiol. 2001;42(1):70–3.

    Article  CAS  PubMed  Google Scholar 

  • Katahira K, Takahara T, Kwee TC, et al. Ultra-high-b-value diffusion-weighted MR imaging for the detection of prostate cancer: evaluation in 201 cases with histopathological correlation. Eur Radiol. 2011;21(1):188–96.

    Article  PubMed  Google Scholar 

  • Kongnyuy M, George AK, Rastinehad AR, et al. Magnetic resonance imaging-ultrasound fusion-guided prostate biopsy: review of technology, techniques, and outcomes. Curr Urol Rep. 2016;17(4):32.

    Article  PubMed  PubMed Central  Google Scholar 

  • Lee DH, Nam JK, Park SW, et al. Visually estimated MRI targeted prostate biopsy could improve the detection of significant prostate cancer in patients with a PSA level <10 ng/mL. Yonsei Med J. 2016;57(3):565–71.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lian H, Zhuang J, Wang W, et al. Assessment of free-hand transperineal targeted prostate biopsy using multiparametric magnetic resonance imaging-transrectal ultrasound fusion in Chinese men with prior negative biopsy and elevated prostate-specific antigen. BMC Urol. 2017;17(1):52.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Ma WK, Ho BS, Lai AS, et al. Multiparametric magnetic resonance imaging/transrectal ultrasound fusion prostate biopsy with semi-robotic navigation in the Chinese population: initial results. Asian J Androl. 2017;20(1):93–4. https://doi.org/10.4103/1008-682X.196855.

    Article  PubMed Central  Google Scholar 

  • Mager R, Brandt MP, Borgmann H, et al. From novice to expert: analyzing the learning curve for MRI-transrectal ultrasonography fusion-guided transrectal prostate biopsy. Int Urol Nephrol. 2017;49(9):1537–44.

    Article  CAS  PubMed  Google Scholar 

  • Mendhiratta N, Rosenkrantz AB, Meng X, et al. MRI-ultrasound fusion-targeted prostate biopsy in a consecutive cohort of men with no previous biopsy: reduction of over-detection through improved risk stratification. J Urol. 2015;194:1601–6.

    Article  PubMed  Google Scholar 

  • Meng X, Rosenkrantz AB, Mendhiratta N, et al. Relationship between prebiopsy multiparametric magnetic resonance imaging (MRI), biopsy indication, and MRI-ultrasound fusion-targeted prostate biopsy outcomes. Eur Urol. 2016;69:512–7.

    Article  PubMed  Google Scholar 

  • Miyagawa T, Ishikawa S, Kimura T, et al. Real-time Virtual Sonography for navigation during targeted prostate biopsy using magnetic resonance imaging data. Int J Urol. 2010;17(10):855–60.

    Article  PubMed  Google Scholar 

  • Moore CM, Robertson NL, Arsanious N, et al. Image-guided prostate biopsy using magnetic resonance imaging-derived targets: a systematic review. Eur Urol. 2013;63(1):125–40.

    Article  PubMed  Google Scholar 

  • Nash PA, Bruce JE, Indudhara R, et al. Transrectal ultrasound guided prostatic nerve blockade eases systematic needle biopsy of the prostate. J Urol. 1996;155(2):607–9.

    Article  CAS  PubMed  Google Scholar 

  • Porpiglia F, Manfredi M, Mele F, et al. Diagnostic pathway with multiparametric magnetic resonance imaging versus standard pathway: results from a randomized prospective study in biopsy-naïve patients with suspected prostate cancer. Eur Urol. 2017;72(2):282–8.

    Article  PubMed  Google Scholar 

  • Portalez D, Mozer P, Cornud F, et al. Validation of the European Society of Urogenital Radiology scoring system for prostate cancer diagnosis on multiparametric magnetic resonance imaging in a cohort of repeat biopsy patients. Eur Urol. 2012;62:986–96.

    Article  PubMed  Google Scholar 

  • Puech P, Rouvière O, Renard-Penna R, et al. Prostate cancer diagnosis: multiparametric MR-targeted biopsy with cognitive and transrectal US-MR fusion guidance versus systematic biopsy—prospective multicenter study. Radiology. 2013;268:461–9.

    Article  PubMed  Google Scholar 

  • Purysko AS, Bittencourt LK, Bullen JA, et al. Accuracy and interobserver agreement for prostate imaging reporting and data system, version 2, for the characterization of lesions identified on multiparametric MRI of the prostate. Am J Roentgenol. 2017;209(2):339–49.

    Article  Google Scholar 

  • Radtke JP, Kuru TH, Boxler S, et al. Comparative analysis of transperineal template saturation prostate biopsy versus magnetic resonance imaging targeted biopsy with magnetic resonance imaging-ultrasound fusion guidance. J Urol. 2015;193:87–94.

    Article  PubMed  Google Scholar 

  • Salami SS, Ben-Levi E, Yaskiv O, et al. In patients with a previous negative prostate biopsy and a suspicious lesion on magnetic resonance imaging, is a 12-core biopsy still necessary in addition to a targeted biopsy? BJU Int. 2015a;115:562–70.

    Article  PubMed  Google Scholar 

  • Salami SS, Ben-Levi E, Yaskiv O, et al. In patients with a previous negative prostate biopsy and a suspicious lesion on magnetic resonance imaging, is a 12-core biopsy still necessary in addition to a targeted biopsy? BJU Int. 2015b;115(4):56270.

    Article  Google Scholar 

  • Siddiqui MM, Rais-Bahrami S, Turkbey B, et al. Comparison of MR/ ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer. JAMA. 2015;313:390–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Soloway MS, Obek C. Periprostatic local anesthesia before ultrasound guided prostate biopsy. J Urol. 2000;163(1):172–3.

    Article  CAS  PubMed  Google Scholar 

  • Sonn GA, Chang E, Natarajan S, et al. Value of targeted prostate biopsy using magnetic resonance-ultrasound fusion in men with prior negative biopsy and elevated prostate-specific antigen. Eur Urol. 2014;65(4):809–15.

    Article  PubMed  Google Scholar 

  • Sonn GA, Natarajan S, Margolis DJ, et al. Targeted biopsy in the detection of prostate cancer using an office based magnetic resonance ultrasound fusion device. J Urol. 2013;189:86–91.

    Article  PubMed  Google Scholar 

  • Tay KJ, Gupta RT, Rastinehad AR, et al. Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls. Expert Rev Anticancer Ther. 2016;16(3):303–11.

    Article  CAS  PubMed  Google Scholar 

  • Venderink W, de Rooij M, Sedelaar JPM, et al. Elastic versus rigid image registration in magnetic resonance imaging-transrectal ultrasound fusion prostate biopsy: a systematic review and meta-analysis. Eur Urol Focus. 2018;4(2):219–27.

    Article  PubMed  Google Scholar 

  • Vourganti S, Rastinehad A, Yerram NK, et al. Multiparametric magnetic resonance imaging and ultrasound fusion biopsy detect prostate cancer in patients with prior negative transrectal ultrasound biopsies. J Urol. 2012;188(6):2152–7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Vourganti S, Starkweather N, Wojtowycz A. MR/US fusion technology: what makes it tick? Curr Urol Rep. 2017;18(3):20.

    Article  PubMed  Google Scholar 

  • Washino S, Okochi T, Saito K, et al. Combination of prostate imaging reporting and data system (PI-RADS) score and prostate-specific antigen (PSA) density predicts biopsy outcome in prostate biopsy naïve patients. BJU Int. 2017;119(2):225–33.

    Article  CAS  PubMed  Google Scholar 

  • Weinreb JC, Barentsz JO, Choyke PL, et al. PI-RADS prostate imaging—reporting and data system: 2015, Version 2. Eur Urol. 2016;69(1):16–40.

    Article  PubMed  Google Scholar 

  • Welch HG, Fisher ES, Gottlieb DJ, et al. Detection of prostate cancer via biopsy in the Medicare-SEER population during the PSA era. J Natl Cancer Inst. 2007;99(18):1395–400.

    Article  PubMed  Google Scholar 

  • Yaxley AJ, Yaxley JW, Thangasamy I, et al. Comparison between target MRI in-gantry and cognitive target transperineal or transrectal guided prostate biopsies for PIRADS 3-5 MRI lesions. BJU Int. 2017;120(Suppl 3):43–50.

    Article  PubMed  Google Scholar 

  • Zhang Q, Wang W, Yang R, et al. Free-hand transperineal targeted prostate biopsy with real-time fusion imaging of multiparametric magnetic resonance imaging and transrectal ultrasound: single-center experience in China. Int Urol Nephrol. 2015;47(5):727–33.

    Article  PubMed  Google Scholar 

  • Zhao C, Gao G, Fang D, et al. The efficiency of multiparametric magnetic resonance imaging (mpMRI) using PI-RADS Version 2 in the diagnosis of clinically significant prostate cancer. Clin Imaging. 2016;40:885–8.

    Article  PubMed  Google Scholar 

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Correspondence to Peter Ka-Fung Chiu .

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Ma, WK., Chiu, P.KF. (2019). MRI-Ultrasound Fusion Prostate Biopsy. In: Chan, Ey., Matsuda, T. (eds) Endourology Progress. Springer, Singapore. https://doi.org/10.1007/978-981-13-3465-8_39

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  • DOI: https://doi.org/10.1007/978-981-13-3465-8_39

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