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Arsenic Exposure and Lifestyle-Related Diseases

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Arsenic Contamination in Asia

Abstract

Arsenic is a naturally occurring toxic metalloid within the Earth’s crust. It is found primarily in drinking water and food. Chronic exposure to high levels of arsenic is associated with a wide range of human diseases including typical skin lesions (hyperpigmentation, hypopigmentation, and keratosis), cancer, diabetes, cardiovascular disease (CVD), neurocognitive outcomes, etc. In this chapter, we will introduce the evidence indicating association between arsenic exposure and increased risks of the lifestyle-related diseases [cancer, type 2 diabetes (T2D), and CVD], including epidemiological studies and animal studies. Current understanding of the mechanisms underlying these diseases and arsenic exposure will also be reviewed.

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  1. School of Public Health, China Medical University, Shenyang, Liaoning, People’s Republic of China

    Yuanyuan Xu, Jingqi Fu, Huihui Wang, Yongyong Hou & Jingbo Pi

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  1. Department of Preventive Medicine, St. Marianna University School of Medicine, Kawasaki, Japan

    Hiroshi Yamauchi

  2. Research Center of Chronic Diseases and Environment, School of Public Health, China Medical University, Shenyang, Liaoning, China

    Guifan Sun

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Xu, Y., Fu, J., Wang, H., Hou, Y., Pi, J. (2019). Arsenic Exposure and Lifestyle-Related Diseases. In: Yamauchi, H., Sun, G. (eds) Arsenic Contamination in Asia. Current Topics in Environmental Health and Preventive Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-13-2565-6_6

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