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Lavandula angustifolia

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Selected References

  • Adaszyńska M, Swarcewicz M, Dzięcioł M, Dobrowolska A (2013) Comparison of chemical composition and antibacterial activity of lavender varieties from Poland. Nat Prod Res 27(16):1497–1501

    PubMed  Google Scholar 

  • Akhondzadeh S, Kashani L, Fotouhi A, Jarvandi S, Mobaseri M, Moin M, Khani M, Jamshidi AH, Baghalian K, Taghizadeh M (2003) Comparison of Lavandula angustifolia Mill. tincture and imipramine in the treatment of mild to moderate depression: a double-blind, randomized trial. Prog Neuropsychopharmacol Biol Psychiatry 27(1):123–127

    PubMed  CAS  Google Scholar 

  • Allardice P (1993) A–Z of companion planting. Angus & Robertson, Pymble, 208 pp

    Google Scholar 

  • Altaei DT (2012) Topical lavender oil for the treatment of recurrent aphthous ulceration. Am J Dent 25(1):39–43

    PubMed  Google Scholar 

  • Bardon S, Foussard V, Fournel S, Loubat A (2002) Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression. Cancer Lett 181(2):187–194

    PubMed  CAS  Google Scholar 

  • Barker SC, Altman PM (2010) A randomised, assessor blind, parallel group comparative efficacy trial of three products for the treatment of head lice in children—melaleuca oil and lavender oil, pyrethrins and piperonyl butoxide, and a “suffocation” product. BMC Dermatol 10:6

    PubMed Central  PubMed  Google Scholar 

  • Basch E, Foppa I, Liebowitz R, Nelson J, Smith M, Sollars D, Ulbricht C (2004) Lavender (Lavandula angustifolia Miller). J Herb Pharmacother 4(2):63–78

    Google Scholar 

  • Behnam S, Farzaneh M, Ahmadzadeh M, Tehrani AS (2006) Composition and antifungal activity of essential oils of Mentha piperita and Lavendula angustifolia on post-harvest phytopathogens. Commun Agric Appl Biol Sci 71(3 Pt B):1321–1326

    PubMed  CAS  Google Scholar 

  • Bertoli A, Conti B, Mazzoni V, Meini L, Pistelli L (2012) Volatile chemical composition and bioactivity of six essential oils against the stored food insect Sitophilus zeamais Motsch. (Coleoptera Dryophthoridae). Nat Prod Res 26(22):2063–2071

    PubMed  CAS  Google Scholar 

  • Blazeković B, Vladimir-Knezević S, Brantner A, Stefan MB (2010) Evaluation of antioxidant potential of Lavandula × intermedia Emeric ex Loisel. ‘Budrovka’: a comparative study with L. angustifolia Mill. Molecules 15(9):5971–5987

    PubMed  Google Scholar 

  • Bown D (1995) Encyclopaedia of herbs and their uses. Dorling Kindersley, London, 424 pp

    Google Scholar 

  • Bradley BF, Starkey NJ, Brown SL, Lea RW (2007) Anxiolytic effects of Lavandula angustifolia odour on the Mongolian gerbil elevated plus maze. J Ethnopharmacol 111(3):517–525

    PubMed  CAS  Google Scholar 

  • Bradley BF, Brown SL, Chu S, Lea RW (2009) Effects of orally administered lavender essential oil on responses to anxiety-provoking film clips. Hum Psychopharmacol Clin Exp 24(4):319–330

    CAS  Google Scholar 

  • Brandão FM (1986) Occupational allergy to lavender oil. Contact Dermatitis 15(4):249–250

    PubMed  Google Scholar 

  • Buchbauer G, Jirovetz L, Jäger W, Dietrich H, Plank C (1991) Aromatherapy: evidence for sedative effects of the essential oil of lavender after inhalation. Z Naturforsch C 46(11–12):1067–1072

    PubMed  CAS  Google Scholar 

  • Büyükokuroğlu ME, Gepdiremen A, Hacimüftüoğlu A, Oktay M (2003) The effects of aqueous extract of Lavandula angustifolia flowers in glutamate-induced neurotoxicity of cerebellar granular cell culture of rat pups. J Ethnopharmacol 84(1):91–94

    PubMed  Google Scholar 

  • Canale A, Benelli G, Conti B, Lenzi G, Flamini G, Francini A, Cioni PL (2013) Ingestion toxicity of three Lamiaceae essential oils incorporated in protein baits against the olive fruit fly, Bactrocera oleae (Rossi) (Diptera Tephritidae). Nat Prod Res 27(22):2091–2099

    PubMed  CAS  Google Scholar 

  • Cassella JP, Cassella S, Ashford R, Siddals E (2001) Antifungal activity of tea tree and lavender essential oils in the treatment of Trichophyton rubrum infection. Focus Altern Complement Ther 6(1):74

    Google Scholar 

  • Chatzopolou PS, Goliaris AH, Katsiotis ST (2003) Contribution to the analysis of the volatile constituents from some lavender and lavandin cultivars grown in Greece. Sci Pharm 71:229–234

    Google Scholar 

  • Chevallier A (1996) The encyclopedia of medicinal plants. Dorling Kindersley, London, 336 pp

    Google Scholar 

  • Chiej R (1984) The Macdonald encyclopaedia of medicinal plants. Macdonald & Co, London, 447 pp

    Google Scholar 

  • Chioca LR, Antunes VD, Ferro MM, Losso EM, Andreatini R (2013a) Anosmia does not impair the anxiolytic-like effect of lavender essential oil inhalation in mice. Life Sci 92(20–21):971–975

    PubMed  CAS  Google Scholar 

  • Chioca LR, Ferro MM, Baretta IP, Oliveira SM, Silva CR, Ferreira J, Losso EM, Andreatini R (2013b) Anxiolytic-like effect of lavender essential oil inhalation in mice: participation of serotonergic but not GABAA/benzodiazepine neurotransmission. J Ethnopharmacol 147(2):412–418

    PubMed  CAS  Google Scholar 

  • Conrad P, Adams C (2012) The effects of clinical aromatherapy for anxiety and depression in the high risk postpartum woman – a pilot study. Complement Ther Clin Pract 18(3):164–168

    PubMed  Google Scholar 

  • Conti B, Canale A, Bertoli A, Gozzini F, Pistelli L (2010) Essential oil composition and larvicidal activity of six Mediterranean aromatic plants against the mosquito Aedes albopictus (Diptera: Culicidae). Parasitol Res 107(6):1455–1461

    PubMed  Google Scholar 

  • D’Auria FD, Tecca M, Strippoli V, Salvatore G, Battinelli L, Mazzanti G (2005) Antifungal activity of Lavandula angustifolia essential oil against Candida albicans yeast and mycelial form. Med Mycol 43(5):391–396

    PubMed  Google Scholar 

  • Da Porto C, Decorti D (2008) Analysis of the volatile compounds of flowers and essential oils from Lavandula angustifolia cultivated in Northeastern Italy by headspace solid-phase microextraction coupled to gas chromatography–mass spectrometry. Planta Med 74(2):182–187

    PubMed  Google Scholar 

  • Da Porto C, Decorti D, Kikic I (2009) Flavour compounds of Lavandula angustifolia L. to use in food manufacturing: comparison of three different extraction methods. Food Chem 112(4):1072–1078

    Google Scholar 

  • Dale A, Cornwell S (1994) The role of lavender oil in relieving perineal discomfort following childbirth: a blind randomized clinical trial. J Adv Nurs 19(1):89–96

    PubMed  CAS  Google Scholar 

  • Danh LT, Triet NDA, Han LTN, Zhao J, Mammucari R, Foster N (2012) Antioxidant activity, yield and chemical composition of lavender essential oil extracted by supercritical CO2. J Supercrit Fluid 70:27–34

    CAS  Google Scholar 

  • De Pascual-Teresa J, Ovejero J, Caballero E, Caballero MC, Anaya J, Pastrana ID (1991) Contribution to the study of lavandin and the lavender oils. An Quim 87:402–404

    CAS  Google Scholar 

  • de Rapper S, Kamatou G, Viljoen A, van Vuuren S (2013) The in vitro antimicrobial activity of Lavandula angustifolia essential oil in combination with other aroma-therapeutic oils. Evid Based Complement Altern Med 2013:852049

    Google Scholar 

  • Denner SS (2009) Lavandula angustifolia Miller: English lavender. Holist Nurs Pract 23(1):57–64

    PubMed  Google Scholar 

  • Dimpfel W, Pischel I, Lehnfeld R (2004) Effects of lozenge containing lavender oil, extracts from hops, lemon balm and oat on electrical brain activity of volunteers. Eur J Med Res 9(9):423–431

    PubMed  CAS  Google Scholar 

  • Duan X, Tashiro M, Wu D, Yambe T, Wang Q, Sasaki T, Kumagai K, Luo Y, Nitta S, Itoh M (2007) Autonomic nervous function and localization of cerebral activity during lavender aromatic immersion. Technol Health Care 15(2):69–78

    PubMed  Google Scholar 

  • Elegbede JA, Elson CE, Qureshi A, Tanner MA, Gould MN (1984) Inhibition of DMBA-induced mammary cancer by the monoterpene d-limonene. Carcinogenesis 5(5):661–664

    PubMed  CAS  Google Scholar 

  • Evandri MG, Battinelli L, Daniele C, Mastrangelo S, Bolle P, Mazzanti G (2005) The antimutagenic activity of Lavandula angustifolia (lavender) essential oil in the bacterial reverse mutation assay. Food Chem Toxicol 43(9):1381–1387

    PubMed  CAS  Google Scholar 

  • Facciola S (1990) Cornucopia. A source book of edible plants. Kampong Publications, Vista, 677 pp

    Google Scholar 

  • Fakhari AR, Salehi P, Heydari R, Ebrahimi SN, Haddad PR (2005) Hydrodistillation-headspace solvent microextraction, a new method for analysis of the essential oil components of Lavandula angustifolia Mill. J Chromatogr A 1098(1–2):14–18

    PubMed  CAS  Google Scholar 

  • Forbes MA, Schmid MM (2006) Use of OTC essential oils to clear plantar warts. Nurs Pract 31(3):53–55, 57

    Google Scholar 

  • Fujii M, Hatakeyama R, Fukuoka Y, Yamamoto T, Sasaki R, Moriya M, Kanno M, Sasaki H (2008) Lavender aroma therapy for behavioral and psychological symptoms in dementia patients. Geratr Geronotol Int 8(2):136–138

    Google Scholar 

  • Fulton GJ, Barber L, Svendsen E, Hagen PO, Davies MG (1997) Oral monoterpene therapy (perillyl alcohol) reduces vein graft intimal hyperplasia. J Surg Res 69(1):128–134

    PubMed  CAS  Google Scholar 

  • Gedney JJ, Glover TL, Fillingim RB (2004) Sensory and affective pain discrimination after inhalation of essential oils. Psychosom Med 66(4):599–606

    PubMed  CAS  Google Scholar 

  • Ghelardini C, Galeotti N, Salvatore G, Mazzanti G (1999) Local anaesthetic activity of the essential oil of Lavandula angustifolia. Planta Med 65(8):700–703

    PubMed  CAS  Google Scholar 

  • Grieve M (1971) A modern herbal. Penguin, 2 vols. Dover Publications, New York. 919 pp

    Google Scholar 

  • Gruncharov V (1973) Clinico-experimental study on the choleretic and cholagogic action of Bulgarian lavender oil. Vutr Boles 12(3):90–96 (in Bulgarian)

    PubMed  CAS  Google Scholar 

  • Guillemain J, Rousseau A, Delaveau P (1989) Neurodepressive effects of the essential oil of Lavandula angustifolia Mill. Ann Pharm Fr 47(6):337–343 (in French)

    PubMed  CAS  Google Scholar 

  • Guitton Y, Nicolè F, Moja S, Valot N, Legrand S, Jullien F, Legendre L (2010) Differential accumulation of volatile terpene and terpene synthase mRNAs during lavender (Lavandula angustifolia and L. × intermedia) inflorescence development. Physiol Plant 138(2):150–163

    PubMed  CAS  Google Scholar 

  • Haag JD, Gould MN (1994) Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene. Cancer Chemother Pharmacol 34(6):477–483

    PubMed  CAS  Google Scholar 

  • Hajhashemi V, Ghannadi A, Sharif B (2003) Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of Lavandula angustifolia Mill. J Ethnopharmacol 89(1):67–71

    PubMed  Google Scholar 

  • Hamad KJ, Al-Shaheen SJA, Kaskoos RA, Ahamad J, Jameel M, Mir SR (2013) Essential oil composition and antioxidant activity of Lavandula angustifolia from Iraq. Int Res J Pharm 4(4):117–120

    CAS  Google Scholar 

  • Hancianu M, Cioanca O, Mihasan M, Hritcu L (2013) Neuroprotective effects of inhaled lavender oil on scopolamine-induced dementia via anti-oxidative activities in rats. Phytomedicine 20(5):446–452

    PubMed  CAS  Google Scholar 

  • Hardy M, Kirk-Smith MD, Stretch DD (1995) Replacement of drug treatment for insomnia by ambient odour. Lancet 346(8976):701

    PubMed  CAS  Google Scholar 

  • Hawrelak JA, Cattley T, Myers SP (2009) Essential oils in the treatment of intestinal dysbiosis: a preliminary in vitro study. Altern Med Rev 14(4):380–384

    PubMed  Google Scholar 

  • Hedrick UP (1972) Sturtevant’s edible plants of the world. Dover Publications, New York, 686 pp

    Google Scholar 

  • Henley DV, Lipson N, Korach KS, Bloch CA (2007) Prepubertal gynecomastia linked to lavender and tea tree oils. N Engl J Med 356(5):479–485

    PubMed  CAS  Google Scholar 

  • Hill AF (1952) Economic botany, 2nd edn. McGraw-Hill Book Co., New York, 560 pp

    Google Scholar 

  • Hirokawa K, Nishimoto T, Taniguchi T (2012) Effects of lavender aroma on sleep quality in healthy Japanese students. Percept Mot Skill 114:111–122

    Google Scholar 

  • Hohmann J, Zupkó I, Rédei D, Csányi M, Falkay G, Máthé I, Janicsák G (1999) Protective effects of the aerial parts of Salvia officinalis, Melissa officinalis and Lavandula angustifolia and their constituents against enzyme-dependent and enzyme-independent lipid peroxidation. Planta Med 65(6):576–578

    PubMed  CAS  Google Scholar 

  • Hritcu L, Cioanca O, Hancianu M (2012) Effects of lavender oil inhalation on improving scopolamine-induced spatial memory impairment in laboratory rats. Phytomedicine 19(6):529–534

    PubMed  CAS  Google Scholar 

  • Huang L, Abuhamdah S, Howes MJ, Dixon CL, Elliot MS, Ballard C, Holmes C, Burns A, Perry EK, Francis PT, Lees G, Chazot PL (2008) Pharmacological profile of essential oils derived from Lavandula angustifolia and Melissa officinalis with anti-agitation properties: focus on ligand-gated channels. J Pharm Pharmacol 60(11):1515–1522

    PubMed  CAS  Google Scholar 

  • Huang MY, Liao MH, Wang YK, Huang YS, Wen HC (2012) Effect of lavender essential oil on LPS-stimulated inflammation. Am J Chin Med 40(4):845–859

    PubMed  Google Scholar 

  • Hudaib MM, Tawaha KA, Mohammad MK, Assaf AM, Issa AY, Alali FQ, Aburjai TA, Bustanji YK (2011) Xanthine oxidase inhibitory activity of the methanolic extracts of selected Jordanian medicinal plants. Pharmacogn Mag 7(28):320–324

    PubMed Central  PubMed  Google Scholar 

  • Hur MH, Yang YS, Lee MS (2008) Aromatherapy massage affects menopausal symptoms in Korean climacteric women: a pilot-controlled clinical trial. Evid Based Complement Altern Med 5(3):325–328

    Google Scholar 

  • Huxley AJ, Griffiths M, Levy M (eds) (1992) The new RHS dictionary of gardening, 4 vols. Macmillan, New York

    Google Scholar 

  • Imanishi J, Kuriyama H, Shigemori I, Watanabe S, Aihara Y, Kita M, Sawai K, Nakajima H, Yoshida N, Kunisawa M, Kawase M, Fukui K (2009) Anxiolytic effect of aromatherapy massage in patients with breast cancer. Evid Based Complement Altern Med 6(1):123–128

    Google Scholar 

  • Jaenson TG, Garboui S, Palsson K (2006) Repellency of oils of lemon eucalyptus, geranium, and lavender and the mosquito repellent MyggA natural to Ixodes ricinus (Acari: Ixodidae) in the laboratory and field. J Med Entomol 43(4):731–736

    PubMed  CAS  Google Scholar 

  • Jäger W, Buchbauer G, Jirovetz L, Fritzer M (1992) Percutaneous absorption of lavender oil from a massage oil. J Soc Cosmet Chem 43(1):49–54

    Google Scholar 

  • Kang HY, Na SS, Kim YK (2010) Effects of oral care with essential oil on improvement in oral health status of hospice patients. J Korean Acad Nurs 40(4):473–481 (in Korean)

    PubMed  Google Scholar 

  • Kashani MS, Tavirani MR, Talaei SA, Salami M (2011) Aqueous extract of lavender (Lavandula angustifolia) improves the spatial performance of a rat model of Alzheimer’s disease. Neurosci Bull 27(2):99–106

    PubMed  Google Scholar 

  • Kasper S, Gastpar M, Müller WE, Volz HP, Möller HJ, Dienel A, Schläfke S (2010) Silexan, an orally administered Lavandula oil preparation, is effective in the treatment of ‘subsyndromal’ anxiety disorder: a randomized, double-blind, placebo controlled trial. Int Clin Psychopharmacol 25(5):277–287

    PubMed  Google Scholar 

  • Kim NS, Lee DS (2002) Comparison of different extraction methods for the analysis of fragrances from Lavandula species by gas chromatography–mass spectrometry. J Chromatogr A 982(1):31–47

    PubMed  CAS  Google Scholar 

  • Kim JT, Ren CJ, Fielding GA, Pitti A, Kasumi T, Wajda M, Lebovits A, Bekker A (2007) Treatment with lavender aromatherapy in the post-anesthesia care unit reduces opioid requirements of morbidly obese patients undergoing laparoscopic adjustable gastric banding. Obes Surg 17(7):920–925

    PubMed  Google Scholar 

  • Kim S, Kim HJ, Yeo JS, Hong SJ, Lee JM, Jeon Y (2011) The effect of lavender oil on stress, bispectral index values, and needle insertion pain in volunteers. J Altern Complement Med 17(9):823–826

    PubMed  Google Scholar 

  • Kim JR, Haribalan P, Son BK, Ahn YJ (2012) Fumigant toxicity of plant essential oils against Camptomyia corticalis (Diptera: Cecdomyiidae). J Econ Entomol 105(4):1329–1334

    PubMed  Google Scholar 

  • Koca Kutlu A, Ceçen D, Gürgen SG, Sayın O, Cetin F (2013) A comparison study of growth factor expression following treatment with transcutaneous electrical nerve stimulation, saline solution, povidone-iodine, and lavender oil in wounds healing. Evid Based Complement Altern Med 2013:361832

    Google Scholar 

  • Koutroumanidou E, Kimbaris A, Kortsaris A, Bezirtzoglou E, Polissiou M, Charalabopoulos K, Pagonopoulou O (2013) Increased seizure latency and decreased severity of pentylenetetrazol-induced seizures in mice after essential oil administration. Epilepsy Res Treat 2013:532657

    PubMed Central  PubMed  Google Scholar 

  • Kritsidima M, Newton T, Asimakopoulou K (2010) The effects of lavender scent on dental patient anxiety levels: a cluster randomised-controlled trial. Community Dent Oral Epidemiol 38(1):83–87

    PubMed  Google Scholar 

  • Lantry LE, Zhang Z, Gao F, Crist KA, Wang Y, Kelloff GJ, Lubet RA, You M (1997) Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung. J Cell Biochem Suppl 27:20–25

    PubMed  CAS  Google Scholar 

  • Launert E (1981) Edible and medicinal plants. Hamlyn, London/New York

    Google Scholar 

  • Lewith GT, Godfrey AD, Prescott P (2005) A single-blinded, randomized pilot study evaluating the aroma of Lavandula augustifolia as a treatment for mild insomnia. J Altern Complement Med 11(4):631–637

    PubMed  Google Scholar 

  • Li XW, Hedge IC (1994) Lamiaceae Lindley. In: Wu ZY, Raven PH (eds) Flora of China, vol 17, Verbenaceae through Solanaceae. Science Press/Missouri Botanical Garden Press, Beijing/St. Louis, 378 pp

    Google Scholar 

  • Lin PW, Chan WC, Ng BF, Lam LC (2007) Efficacy of aromatherapy (Lavandula angustifolia) as an intervention for agitated behaviours in Chinese older persons with dementia: a cross-over randomized trial. Int J Geriatr Psychiatry 22(5):405–410

    PubMed  Google Scholar 

  • Lis-Balchin M, Hart S (1999) Studies on the mode of action of the essential oil of lavender (Lavandula angustifolia P. Miller). Phytother Res 13(6):540–542

    PubMed  CAS  Google Scholar 

  • Liston BW, Nines R, Carlton PS, Gupta A, Aziz R, Frankel W, Stoner GD (2003) Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. Cancer Res 63(10):2399–2403

    PubMed  CAS  Google Scholar 

  • Lodhia MH, Bhatt KR, Thaker VS (2009) Antibacterial activity of essential oils from palmarosa, evening primrose, lavender and tuberose. Indian J Pharm Sci 71(2):134–136

    PubMed Central  PubMed  CAS  Google Scholar 

  • Lu H, Li H, Lu H, Li XL, Zhou AG (2010) Chemical composition of lavender essential oil and its antioxidant activity and inhibition against rhinitis related bacteria. Afr J Microbiol Res 4(4):309–313

    CAS  Google Scholar 

  • Lust JB (1974) The herb book. Bantam Books, New York, 174 pp

    Google Scholar 

  • Mahady GB, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR (2005) In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother Res 19(11):988–991

    PubMed  Google Scholar 

  • Matos JM, Schmidt CM, Thomas HJ, Cummings OW, Wiebke EA, Madura JA, Patrick LJ Sr, Crowell PL (2008) A pilot study of perillyl alcohol in pancreatic cancer. J Surg Res 147(2):194–199

    PubMed  CAS  Google Scholar 

  • Matsumoto T, Asakura H, Hayashi T (2013) Does lavender aromatherapy alleviate premenstrual emotional symptoms?: a randomized crossover trial. Biopsychosoc Med 7(1):12

    PubMed Central  PubMed  Google Scholar 

  • Miladinović DL, Ilić BS, Mihajilov-Krstev TM, Nikolić ND, Miladinović LC, Cvetković OG (2012) Investigation of the chemical composition-antibacterial activity relationship of essential oils by chemometric methods. Anal Bioanal Chem 403(4):1007–1018

    PubMed  Google Scholar 

  • Milina R, Mustafa Z, Stanev S, Zvezdova D, Stoeva S (2012) Headspace gas chromatographic analysis of Bulgarian Lavandula angustifolia Mill herbs. I. Optimization of the analysis conditions. Научни Трудове На Русенския Университет (Scientific Works of The University (Bulgarian) 51(9.1):50–56

    Google Scholar 

  • Mills JJ, Chari RS, Boyer IJ, Gould MN, Jirtle RL (1995) Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol. Cancer Res 55:979

    PubMed  CAS  Google Scholar 

  • Mkolo MN, Magano SR (2007) Repellent effects of the essential oil of Lavendula angustifolia against adults of Hyalomma marginatum rufipes. J S Afr Vet Assoc 78(3):149–152

    PubMed  CAS  Google Scholar 

  • Moeini M, Khadibi M, Bekhradi R, Mahmoudian SA, Nazari F (2010) Effect of aromatherapy on the quality of sleep in ischemic heart disease patients hospitalized in intensive care units of heart hospitals of the Isfahan University of Medical Sciences. Iran J Nurs Midwifery Res 15(4):234

    PubMed Central  PubMed  Google Scholar 

  • Moon T, Wilkinson JM, Cavanagh HM (2006) Antiparasitic activity of two Lavandula essential oils against Giardia duodenalis, Trichomonas vaginalis and Hexamita inflata. Parasitol Res 99(6):722–728

    PubMed  Google Scholar 

  • Moss M, Cook J, Wesnes K, Duckett P (2003) Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults. Int J Neurosci 113(1):15–38

    PubMed  Google Scholar 

  • Nord D, Belew J (2009) Effectiveness of the essential oils lavender and ginger in promoting children’s comfort in a perianesthesia setting. J Perianesth Nurs 24(5):307–312

    PubMed  Google Scholar 

  • Panahi Y, Akhavan A, Sahebkar A, Hosseini SM, Taghizadeh M, Akbari H, Sharif MR, Imani S (2013) Investigation of the effectiveness of Syzygium aromaticum, Lavandula angustifolia and Geranium robertianum essential oils in the treatment of acute external otitis: a comparative trial with ciprofloxacin. J Microbiol Immunol Infect S1684–1182(12):00214–00219

    Google Scholar 

  • Pavela R (2005) Insecticidal activity of some essential oils against larvae of Spodoptera littoralis. Fitoterapia 76(7–8):691–696

    PubMed  CAS  Google Scholar 

  • Pemberton E, Turpin PG (2008) The effect of essential oils on work-related stress in intensive care unit nurses. Holist Nurs Pract 22(2):97–102

    PubMed  Google Scholar 

  • Perrucci S, Cioni PL, Flamini G, Morelli I, Macchioni G (1994) Acaricidal agents of natural origin against Psoroptes cuniculi. Parassitologia 36(3):269–271

    PubMed  CAS  Google Scholar 

  • Perrucci S, Macchioni G, Cioni PC, Flamini G, Morelli I, Taccini F (1996) The activity of volatile compounds from Lavandula angustifolia against Psoroptes cuniculi. Phytother Res 10:5–8

    CAS  Google Scholar 

  • Perry R, Terry R, Watson LK, Ernst E (2012) Is lavender an anxiolytic drug? A systematic review of randomised clinical trials. Phytomedicine 19(8–9):825–835

    PubMed  CAS  Google Scholar 

  • Phillips R, Foy N (1992) Herbs. Pan Macmillan Limited, London, 192 pp

    Google Scholar 

  • Pirali-Kheirabadi K, Teixeira da Silva JA (2010) Lavandula angustifolia essential oil as a novel and promising natural candidate for tick (Rhipicephalus (Boophilus) annulatus) control. Exp Parasitol 126(2):184–186

    PubMed  CAS  Google Scholar 

  • Prashar A, Locke IC, Evans CS (2004) Cytotoxicity of lavender oil and its major components to human skin cells. Cell Prolif 37(3):221–229

    PubMed  CAS  Google Scholar 

  • Rademaker M (1994) Allergic contact dermatitis from lavender fragrance in Difflam gel. Contact Dermatitis 31(1):58–59

    PubMed  CAS  Google Scholar 

  • Raina AP, Negi KS (2012) Comparative essential oil composition of Lavendula species from India. J Herb Spice Med Plant 18(3):268–273

    CAS  Google Scholar 

  • Reddy BS, Wang CX, Samaha H, Lubet R, Steele VE, Kelloff GJ, Rao CV (1997) Chemoprevention of colon carcinogenesis by dietary perillyl alcohol. Cancer Res 57:420

    PubMed  CAS  Google Scholar 

  • Ren Z, Gould MN (1994) Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol. Cancer Lett 76(2–3):185–190

    PubMed  CAS  Google Scholar 

  • Renaud EN, Charles DJ, Simon JE (2001) Essential oil quantity and composition from 10 cultivars of organically grown lavender and lavandin. J Essent Oil Res 13(4):269–273

    CAS  Google Scholar 

  • Riotte L (1978) Companion planting for successful gardening. Garden Way, Vermont

    Google Scholar 

  • Ripple GH, Gould MN, Stewart JA, Tutsch KD, Arzoomanian RZ, Alberti D, Feierabend C, Pomplun M, Wilding G, Bailey HH (1998) Phase I clinical trial of perillyl alcohol administered daily. Clin Cancer Res 4(5):1159–1164

    PubMed  CAS  Google Scholar 

  • Ripple GH, Gould MN, Arzoomanian RZ, Alberti D, Feierabend C, Simon K, Binger K, Tutsch KD, Pomplun M, Wahamaki A, Marnocha R, Wilding G, Bailey HH (2000) Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day. Clin Cancer Res 6(2):390–396

    PubMed  CAS  Google Scholar 

  • Robu S, Aprotosoaie AC, Spac A, Cioancă O, Hăncianu M, Stănescu U (2011) Studies regarding chemical composition of lavender volatile oils. Rev Med Chir Soc Med Nat Iasi 115(2):584–589 (in Romanian)

    PubMed  Google Scholar 

  • Roller S, Ernest N, Buckle J (2009) The antimicrobial activity of high-necrodane and other lavender oils on methicillin-sensitive and -resistant Staphylococcus aureus (MSSA and MRSA). J Altern Complement Med 15(3):275–279

    PubMed  Google Scholar 

  • Rota C, Carramiñana JJ, Burillo J, Herrera A (2004) In vitro antimicrobial activity of essential oils from aromatic plants against selected foodborne pathogens. J Food Prot 67(6):1252–1256

    PubMed  CAS  Google Scholar 

  • Sayorwan W, Siripornpanich V, Piriyapunyaporn T, Hongratanaworakit T, Kotchabhakdi N, Ruangrungsi N (2012) The effects of lavender oil inhalation on emotional states, autonomic nervous system, and brain electrical activity. J Med Assoc Thai 95(4):598–606

    PubMed  Google Scholar 

  • Schaller M, Korting HC (1995) Allergic airborne contact dermatitis from essential oils used in aromatherapy. Clin Exp Dermatol 20(2):143–145

    PubMed  CAS  Google Scholar 

  • Seol GH, Lee YH, Kang P, You JH, Park M, Min SS (2013) Randomized controlled trial for Salvia sclarea or Lavandula angustifolia: differential effects on blood pressure in female patients with urinary incontinence undergoing urodynamic examination. J Altern Complement Med 19(7):664–670

    PubMed  Google Scholar 

  • Sheikhan F, Jahdi F, Khoei EM, Shamsalizadeh N, Sheikhan M, Haghani H (2012) Episiotomy pain relief: use of lavender oil essence in primiparous Iranian women. Complement Ther Clin Pract 18(1):66–70

    PubMed  Google Scholar 

  • Shi W, Gould MN (1995) Induction of differentiation in neuro-2A cells by the monoterpene perillyl alcohol. Cancer Lett 95(1–2):1–6

    PubMed  CAS  Google Scholar 

  • Shi W, Gould MN (2002) Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol. Carcinogenesis 23(1):131–142

    PubMed  CAS  Google Scholar 

  • Shiina Y, Funabashi N, Lee K, Toyoda T, Sekine T, Honjo S, Hasegawa R, Kawata T, Wakatsuki Y, Hayashi S, Murakami S, Koike K, Daimon M, Komuro I (2008) Relaxation effects of lavender aromatherapy improve coronary flow velocity reserve in healthy men evaluated by transthoracic Doppler echocardiography. Int J Cardiol 129(2):193–197

    PubMed  Google Scholar 

  • Shimada K, Fukuda S, Maeda K, Kawasaki T, Kono Y, Jissho S, Taguchi H, Yoshiyama M, Yoshikawa J (2011) Aromatherapy alleviates endothelial dysfunction of medical staff after night-shift work: preliminary observations. Hypertens Res 34(2):264–267

    PubMed  Google Scholar 

  • Shimizu K, Gyokusen M, Kitamura S, Kawabe T, Kozaki T, Ishibashi K, Izumi R, Mizunoya W, Ohnuki K, Kondo R (2008) Essential oil of lavender inhibited the decreased attention during a long-term task in humans. Biosci Biotechnol Biochem 72(7):1944–1947

    PubMed  CAS  Google Scholar 

  • Sienkiewicz M, Kalemba D, Wasiela M (2011a) Sensitivity assessment of thyme and lavender essential oils against clinical strains of Escherichia coli for their resistance. Med Dosw Mikrobiol 63(3):273–281 (in Polish)

    PubMed  CAS  Google Scholar 

  • Sienkiewicz M, Łysakowska M, Ciećwierz J, Denys P, Kowalczyk E (2011b) Antibacterial activity of thyme and lavender essential oils. Med Chem 7(6):674–689

    PubMed  CAS  Google Scholar 

  • Silenieks LB, Koch E, Higgins GA (2013) Silexan, an essential oil from flowers of Lavandula angustifolia, is not recognized as benzodiazepine-like in rats trained to discriminate a diazepam cue. Phytomedicine 20(2):172–177

    PubMed  CAS  Google Scholar 

  • Sinthusiri J, Soonwera M (2013) Efficacy of herbal essential oils as insecticides against the housefly, Musca domestica L. Southeast Asian J Trop Med Public Health 44(2):188–196

    PubMed  Google Scholar 

  • Smigielski K, Raj A, Krosowiak K, Gruska R (2009) Chemical composition of the essential oil of Lavandula angustifolia cultivated in Poland. J Essent Oil Bear Plant 12(3):338–347

    CAS  Google Scholar 

  • Soković M, Glamočlija J, Marin PD, Brkić D, van Griensven LJ (2010) Antibacterial effects of the essential oils of commonly consumed medicinal herbs using an in vitro model. Molecules 15(11):7532–7546

    PubMed  Google Scholar 

  • Soltani R, Soheilipour S, Hajhashemi V, Asghari G, Bagheri M, Molavi M (2013) Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial. Int J Pediatr Otorhinolaryngol 77(9):1579–1581

    PubMed  Google Scholar 

  • Spiridon I, Colceru S, Anghel N, Teaca CA, Bodirlau R, Armatu A (2011) Antioxidant capacity and total phenolic contents of oregano (Origanum vulgare), lavender (Lavandula angustifolia) and lemon balm (Melissa officinalis) from Romania. Nat Prod Res 25(17):1657–1661

    PubMed  CAS  Google Scholar 

  • Stark MJ, Burke YD, McKinzie JH, Ayoubi AS, Crowel PL (1995) Chemotherapy of pancreatic cancer with the monoterpene perillyl alcohol. Cancer Lett 96(1):15–21

    PubMed  CAS  Google Scholar 

  • Sugiura M, Hayakawa R, Kato Y, Sugiura K, Hashimoto R (2000) Results of patch testing with lavender oil in Japan. Contact Dermatitis 43(3):157–160

    PubMed  CAS  Google Scholar 

  • Talbert R, Wall R (2012) Toxicity of essential and non-essential oils against the chewing louse, Bovicola (Werneckiella) ocellatus. Res Vet Sci 93(2):831–835

    PubMed  CAS  Google Scholar 

  • Topçu G, Herrmann G, Kolak U, Gören C, Porzel A, Kutchan TM (2007) Isolation of fatty acids and aromatics from cell suspension cultures of Lavandula angustifolia. Nat Prod Res 21(2):100–105

    PubMed  Google Scholar 

  • Tschiggerl C, Bucar F (2010) Volatile fraction of lavender and bitter fennel infusion extracts. Nat Prod Commun 5(9):1431–1436

    PubMed  CAS  Google Scholar 

  • Uehleke B, Schaper S, Dienel A, Schlaefke S, Stange R (2012) Phase II trial on the effects of Silexan in patients with neurasthenia, post-traumatic stress disorder or somatization disorder. Phytomedicine 19(8):665–671

    PubMed  CAS  Google Scholar 

  • Uphof JCT (1968) Dictionary of economic plants, 2nd ed. (1st ed. 1959). Cramer, Lehre. 591 pp

    Google Scholar 

  • van der Ploeg ES, Eppingstall B, O’Connor DW (2010) The study protocol of a blinded randomised-controlled cross-over trial of lavender oil as a treatment of behavioural symptoms in dementia. BMC Geriatr 10:49. doi:10.1186/1471-2318-10-49

    PubMed Central  PubMed  Google Scholar 

  • Verma RS, Rahman LU, Chanotiya CS, Verma RK, Chauhan A, Yadav A, Singh A, Yadav AK (2010) Essential oil composition of Lavandula angustifolia Mill. cultivated in the mid hills of Uttarakhand, India. J Serb Chem Soc 75(3):343–348

    CAS  Google Scholar 

  • Wang D, Yuan X, Liu T, Liu L, Hu Y, Wang Z, Zheng Q (2012) Neuroprotective activity of lavender oil on transient focal cerebral ischemia in mice. Molecules 17(8):9803–9817

    PubMed  CAS  Google Scholar 

  • Williams TI (2006) Evaluating effects of aromatherapy massage on sleep in children with autism: a pilot study. Evid Based Complement Altern Med 3(3):373–377

    Google Scholar 

  • Wilson H (2013) Chelsea flower show: guide to edible flowers. http://food.uk.msn.com/food/edible-flowers-chelsea-flower-show?page=3#image=6. Accessed Nov 2013

  • Woelk H, Schläfke S (2010) A multi-center, double-blind, randomised study of the lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder. Phytomedicine 17(2):94–99

    PubMed  CAS  Google Scholar 

  • Wu X, Liu J, Yu ZB, Ye YH, Zhou YW (2007) Studies on flavones in of Lavandula augustifolia. Zhongguo Zhong Yao Za Zhi 32(9):821–823 (in Chinese)

    PubMed  CAS  Google Scholar 

  • Xu F, Uebaba K, Ogawa H, Tatsuse T, Wang BH, Hisajima T, Venkatraman S (2008) Pharmaco-physio-psychologic effect of Ayurvedic oil-dripping treatment using an essential oil from Lavendula angustifolia. J Altern Complement Med 14(8):947–956

    PubMed  Google Scholar 

  • Yamada K, Mimaki Y, Sashida Y (1994) Anticonvulsive effects of inhaling lavender oil vapour. Biol Pharm Bull 17(2):359–360

    PubMed  CAS  Google Scholar 

  • Yang J, Gao FL (2010) Study on antioxidant activities of total flavonoids from Lavandula angustifolia of Xinjiang. China Food Addit 2:162–165

    Google Scholar 

  • Yusufoglu A, Çelik H, Kirbsalar GF (2004) Utilization of Lavandula angustifolia Miller extracts as natural repellents, pharmaceutical and industrial auxiliaries. J Serb Chem Soc 60(1):1–7

    Google Scholar 

  • Zhang Z, Chen H, Chan KK, Budd T, Ganapathi R (1999) Gas chromatographic-mass spectrometric analysis of perillyl alcohol and metabolites in plasma. J Chromatogr B Biomed Sci Appl 728(1):85–95

    PubMed  CAS  Google Scholar 

  • Zheljazkov VD, Cantrell CL, Astatkie T, Jeliazkova E (2013) Distillation time effect on lavender essential oil yield and composition. J Oleo Sci 62(4):195–199

    PubMed  CAS  Google Scholar 

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Lim, T.K. (2014). Lavandula angustifolia. In: Edible Medicinal and Non Medicinal Plants. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-8748-2_8

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