Abstract
Hepatic hydatid disease is also called echinococcosis of the liver. It is a kind of parasitic zoonosis caused by infection with the larva of echinococcus in the visceral organs of human beings and other animals. After infection with echinococcus has occurred, the larva of echinococcus can parasitize many organs in the body. The liver is the most commonly affected organ and accounts for approximately 70 % of cases, followed by the lung, which accounts for 20 % of cases. It can be also observed in other organs, such as the brain, heart, kidney, orbit, and bone marrow cavity, which accounts for approximately 10 % [1]. Hepatic hydatid disease has been reported all around the world, and the prevalence is more severe in pastoral areas. Most of the locations where hydatid disease is prevalent are pastoral areas where economic conditions and medical conditions are very poor, and most patients are herdsmen who have no ability to afford hospitalization costs. Therefore, hepatic hydatid disease has become a severe public health problem in epidemic areas. Over the past few years, the thriving development of immigration and tourism has caused a high level of migratory movement, which has resulted in reports of hepatic hydatid disease in many non-epidemic areas [2, 3]. For this reason, the disease is becoming a global public health problem [4, 5]. Sixteen species and 13 subspecies of echinococcus have been found so far, but only five of them have important clinical significance: Echinococcus granulosus, Echinococcus multilocularis, Echinococcus oligarthrus, Echinococcus vogeli, and Echinococcus shiquicus, which were recently discovered in Shi Qu County of Sichuan Province [6]. Among them, E. granulosus is the most commonly reported all around the world. Infection with E. granulosus causes cystic echinococcosis, which is most commonly found in a clinical environment. E. multilocularis is rarely reported worldwide, but the incidence is very high in the Ganzi prefecture of Sichuan Province. Alveolar echinococcosis caused by E. multilocularis develops like a malignant tumor. It is a type of highly pathogenic disease that leads to high mortality, which has important clinical significance. This chapter focuses on these two kinds of echinococcosis.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Grosso G, Gruttadauria S, Biondi A, et al. Worldwide epidemiology of liver hydatidosis including the Mediterranean area. World J Gastroenterol. 2012;18(13):1425–37.
Morakote N, Thamprasert K, Lojanapiwat B, et al. Cystic echinococcosis in Thailand with a special note on detection by serology in one family. Southeast Asian J Trop Med Public Health. 2007;38:796–8.
Maoz D, Greif F, Chen J. Operative treatment of hepatic hydatid cysts: a single center experience in Israel, a nonendemic country. ISRN Surg. 2013;2013:276807.
Eckert J, Conraths FJ, Tackmann K. Echinococcosis: an emerging or re-emerging zoonosis? Int J Parasitol. 2000;30:1283–94.
Eckert J, Schantz PM, Gasser RB, et al. Geographic distribution and prevalence. In: Eckert J, Gemmell MA, Meslin FX, Pawlowski Z, editors. WHO/OIE manual on echinococcosis in humans and animals: a public health problem of global concern. Paris: Office International des Epizooties Paris; 2001. p. 100–42.
Xiao N, Qiu JM, Nakao M, et al. Echinococcus shiquicus n. sp., a taeniid cestode from Tibetan fox and plateau pika in China. Int J Parasitol. 2005;35:693–701.
Mergen H, Genç H, Tavusbay C. Assessment of liver hydatid cyst cases — 10 years experience in Turkey. Trop Doct. 2007;37:54–6.
Alghoury A, El-Hamshary E, Azazy A, et al. Hydatid disease in Yemeni patients attending public and private hospitals in Sana’a City. Yemen Oman Med J. 2010;25:88–90.
Landen S, Van de Sande J, Berger P, et al. Alveolar echinococcosis in a Belgian urban dweller. Acta Gastroenterol Belg. 2013;76:317–21.
Gourgiotis S, Stratopoulos C, Moustafellos P, et al. Surgical techniques and treatment for hepatic hydatid cysts. Surg Today. 2007;37:389–95.
Bilge A, Sözüer EM, et al. Diagnosis and surgical treatment of hepatic hydatid disease. HPB Surg. 1992;6:57–64.
Nagarajan K, Sekar D, Babu JV, et al. Hydatid cyst of the liver causing inferior vena caval obstruction. J Assoc Physicians India. 2013;61:671–3.
Sandonato L, Cipolla C, Li Petri S, et al. Giant hepatic hydatid cyst as a cause of small bowel obstruction. Am Surg. 2006;72:405–8.
Adas G, Arikan S, Gurbuz E, et al. Comparison of endoscopic therapeutic modalities for postoperative biliary fistula of liver hydatid cyst: a retrospective multicentric study. Surg Laparosc Endosc Percutan Tech. 2010;20:223–7.
Derici H, Tansug T, Reyhan E, et al. Acute intraperitoneal rupture of hydatid cysts. World J Surg. 2006;30:1879–85.
Elmali M, Ceyhan M, Ilgar M, et al. Hepatic hydatid cyst rupture and anaphylaxis after a fall. Indian J Pediatr. 2009;76:329–30.
Daldoul S, Moussi A, Zaouche A. Spontaneous fistulization of hepatic hydatid cyst into the duodenum: an exceptional complication. J Coll Physicians Surg Pak. 2013;23:424–6.
Serraj M, Smahi M, Kamaoui I, et al. Hydatic pulmonary embolism: a rare complication of hepatic hydatid cyst. Rev Mal Respir. 2013;30:215–21.
Kayaalp C, Bzeizi K, Demirbag AE, et al. Biliary complications after hydatid liver surgery: incidence and risk factors. J Gastrointest Surg. 2002;6:706–12.
Ray R, De PK, Karak K. Combined role of Casoni test and indirect haemagglutination test in the diagnosis of hydatid disease. Indian J Med Microbiol. 2002;20:79–82.
Brunetti E, Kern P, Vuitton DA. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop. 2010;114:1–16.
Siracusano A, Bruschi F. Cystic echinococcosis: progress and limits in epidemiology and immunodiagnosis. Parassitologia. 2006;48:65–6.
Ito A, Craig PS. Immunodiagnostic and molecular approaches for the detection of Taeniid cestode infections. Trends Parasitol. 2003;19:377–81.
Eckert J, Deplazes P. Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clin Microbiol Rev. 2004;17:107–35.
Galitza Z, Bazarsky E, Sneier R, et al. Repeated treatment of cystic echinococcosis in patients with a long-term immunological response after successful surgical cyst removal. Trans R Soc Trop Med Hyg. 2006;100:126–33.
Giorgio A, Tarantino L, de Stefano G, et al. Complications after interventional sonography of focal liver lesions: a 22-year single-center experience. J Ultrasound Med. 2003;22:193–205.
Leslie H, Blumgart LH. Echinococcosis of liver. In: Surgery of the liver, biliary tract and pancreas. 4th ed. Singapore: Elsevier Science; 2010. p. 946–63.
WHO Informal Working Group. International classification of ultrasound images in cystic echinococcosis for application in clinical and field epidemiological settings. Acta Trop. 2003;85:253–61.
Eckert J, et al. WHO/OEI manual on echinococcosis in humans and animals: a public health problem of global concern. Paris: World Organization for Animal Health; 2000. p. 20–71.
Gil-Grande LA, Rodriguez-Caabeiro F, Prieto JG, et al. Randomised controlled trial of efficacy of albendazole in intra-abdominal hydatid disease. Lancet. 1993;342:1269–72.
Tagliacozzo S. Management of hydatid disease of the liver. In: Poston GJ, Blumgart LH, editors. Surgical management of hepatobiliary and pancreatic disorders. New York: Martin Dunitz; 2003. p. 215–35.
Birnbaum DJ, Hardwigsen J, Barbier L, et al. Is hepatic resection the best treatment for hydatid cyst? J Gastrointest Surg. 2086–2093;16(11):2012.
WHO Informal Working Group on Echinococcosis. Guidelines for treatment of cystic and alveolar echinococcosis in humans. Bull World Health Organ. 1996;74:231–42.
Aydin U, Yazici P, Onen Z, Ozsoy M, Zeytunlu M, Kilic M, Coker A. The optimal treatment of hydatid cyst of the liver: radical surgery with a significant reduced risk of recurrence. Turk J Gastroenterol. 2008;19:33–9.
Baskaran V, Patnaik PK. Feasibility and safety of laparoscopic management of hydatid disease of the liver. JSLS. 2004;8:359–63.
Akbulut S, Senol A, Sezgin A, et al. Radical VS conservative surgery for hydatid liver cysts: experience from single center. World J Gastroenterol. 2010;16(8):953–9.
Silva MA, Mirza DF, Bramhall SR, et al. Treatment of hydatid disease of the liver. Dig Surg. 2004;21:227–34.
Gollackner B, Längle F, Auer H, et al. Radical surgical therapy of abdominal cystic hydatid disease: factors of recurrence. World J Surg. 2000;24:717–21.
Safioleas M, Misiakos E, Manti C, et al. Diagnostic evaluation and surgical management of hydatid disease of the liver. World J Surg. 1994;18:859–65.
Bilge A, Sozuer EM. Diagnosis and surgical treatment of hepatic hydatid disease. HPB Surg. 1994;8:77–81.
Abu Zeid M, El-Eibiedy G, Abu-El-Einien A, et al. Surgical treatment of hepatic hydatid cysts. Hepatogastroenterology. 1998;45:1802–6.
WHO/OIE. Manual on echinococcosis. Echinococcosis in humans and animals: a public health problem of global concern. Paris: World Organisation for Animal Health (Office International des Epizooties) and World Health Organisation; 2001.
Brunettia E, Kern P, Vuitton DA, Writing Panel for the WHO-IWG. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. Acta Trop. 2010;114:1–16.
Atanasov G, Benckert C, Thelen A, et al. Alveolar echinococcosis—spreading disease challenging clinicians: a case report and literature review. World J Gastroenterol. 2013;19:4257–61.
Buttenschoen K, Carli Buttenschoen D, Gruener B, Kern P, Beger HG, Henne-Bruns D, Reuter S. Long-term experience on surgical treatment of alveolar echinococcosis. Langenbecks Arch Surg. 2009;394:698.
Kadry Z, Renner EC, Bachmann LM, Attigah N, Renner EL, Ammann RW, Clavien PA. Evaluation of treatment and long-term follow-up in patients with hepatic alveolar echinococcosis. Br J Surg. 2005;92:1110–6.
Buttenschoen K, Gruener B, et al. Palliative operation for the treatment of alveolar echinococcosis. Langenbecks Arch Surg. 2009;394:199–204.
Koch S, Bresson-Hadni S, Miguet JP, Crumbach JP, Gillet M, Mantion GA, Heyd B, Vuitton DA, Minello A, Kurtz S. Experience of liver transplantation for incurable alveolar echinococcosis: a 45-case European collaborative report. Transplantation. 2003;75:856–63.
Vuitton D, Zhang SL, Yang Y, Godot V, Beurton I, Mantion G, Bresson-Hadni S. Survival strategy of Echinococcus multilocularis in the human host. Parasitol Int. 2006;55(Suppl):S51–5.
Wen H, Dong JH, et al. Ex vivo liver resection followed by autotransplantation for end-stage hepatic alveolar echinococcosis. Chin Med J (Engl). 2011;124(18):2813–7.
Wang H, Liu Q. Clinical outcomes of ex vivo liver resection and liver autotransplantation for hepatic alveolar echinococcosis. J Huazhong Univ Sci Technol [Med Sci]. 2012;32(4):598–600.
Mantion GA, Vuitton DA. Auto-versus allo-transplantation of the liver for end-stage alveolar echinococcosis? Chin Med J. 2011;124(18):2803–5.
Dziri C, Haouet K, Fingerhut A, Zaouche A. Management of cystic echinococcosis complications and dissemination: where is the evidence? World J Surg. 2009;33:1266–73.
Tocchi A, Mazzoni G, Miccini M, Drumo A, Cassini D, Colace L, Tagliacozzo S. Treatment of hydatid bronchobiliary fistulas: 30 years of experience. Liver Int. 2007;27:209–14.
Simsek H, Ozaslan E, Sayek I, Savas C, Abbasoglu O, Soylu AR, Balaban Y, Tatar G. Diagnostic and therapeutic ERCP in hepatic hydatid disease. Curr Gastroenterol Rep. 2004;6:272.
Galati G, Sterpetti AV, Caputo M, Adduci M, Lucandri G, Brozzetti S, Bolognese A, Cavallaro A. Endoscopic retrograde cholangiography for intrabiliary rupture of hydatid cyst. Am J Surg. 2006;191:206–10.
Eickhoff A, et al. Endoscopic stenting for postoperative biliary strictures due to hepatic hydatid disease: effectiveness and long-term outcome. J Clin Gastroenterol. 2003;37:74–8.
Junghanss T, Menezes da Silva A, Horton J, Chiodini PL, Brunetti E. Clinical management of cystic echinococcosis: state of the art, problems, and perspectives. Am J Trop Med Hyg. 2008;79:301–11.
Bresson-Hadni S, Koch S, Miguet JP, Gillet M, Mantion GA, Heyd B, Vuitton DA. Indications and results of liver transplantation for Echinococcus alveolar infection: an overview. Langenbecks Arch Surg. 2003;388:231–8.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Chen, Z. (2016). Liver Resection in Hepatic Hydatid Disease. In: Yan, L. (eds) Operative Techniques in Liver Resection. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-7411-6_19
Download citation
DOI: https://doi.org/10.1007/978-94-017-7411-6_19
Published:
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-017-7409-3
Online ISBN: 978-94-017-7411-6
eBook Packages: MedicineMedicine (R0)