Abstract
LH and FSH, known to be secreted already in utero and in early infancy (Faiman and Winter, 1971), activate the production of both male and female gonadal hormones (Forest et al., 1973; Bidlingmaier and Knorr, 1978). In the clinic LHRH is most frequently used for diagnostic purposes, to test the integrity of the hypothalamic—pituitary—gonadal axis. Experience in many clinics has led to a number of test procedures which are based on common principles but differ in the dosage employed and the mode of administration. The physiological basis for the LHRH test is the ability of LHRH, whether administered intravenously or intramuscularly, to induce secretion of the pool of pituitary LH and FSH which in normal circumstances is readily releasable. This review of diagnostic procedures emphasizes the experience gained in our clinic during the past 10 years in performing several thousand LHRH tests, mainly in children.
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Laron, Z., Prager-Lewin, R., Dickerman, Z. (1984). Diagnostic uses of LHRH. In: Vickery, B.H., Nestor, J.J., Hafez, E.S.E. (eds) LHRH and Its Analogs. Advances in Reproductive Health Care, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5588-2_28
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DOI: https://doi.org/10.1007/978-94-009-5588-2_28
Publisher Name: Springer, Dordrecht
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