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Molecular Composition Study of Mumijo from Different Geographic Areas Using Size-Exclusion Chromatography, NMR Spectroscopy, and High-Resolution Mass Spectrometry

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Functions of Natural Organic Matter in Changing Environment

Abstract

Four mumijo samples originated from different mountain ranges were studied using size-exclusion chromatography (SEC), Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS), and 1H and 13C NMR spectroscopy. All the used analytical techniques demonstrated that the mumijo samples studied consist of a “high-molecular” fulvic-like and a low-molecular components. The second component is shown using FTICR MS and NMR methods to be predominantly a range of vegetative and animal metabolites.

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References

  • Agarwal, S.P., R. Khanna, R. Karmarkar, M.K. Anwer, and R.K. Khar. 2007. Shilajit: A review. Phytotherapy Research 21: 401–405.

    Article  Google Scholar 

  • Frolova, L.N., and T.L. Kiseleva. 1996. Chemical composition of mumijo and methods for determining its authenticity and quality (a review). Pharmaceutical Chemistry Journal 30: 543–547 DOI: 10.1007/BF02334644.

    Article  Google Scholar 

  • Khanna, R., M. Witt, M.K. Anwer, S.P. Agarwal, and B.P. Koch. 2008. Spectroscopic characterization of fulvic acids extracted from the rock exudate Shilajit. Organic Geochemistry 39: 1719–1724.

    Article  CAS  Google Scholar 

  • Perminova, I.V., F.H. Frimmel, A.V. Kudryavtsev, N.A. Kulikova, G. Abbt-Braun, S. Hesse, and V.S. Petrosyan. 2003. Molecular weight characteristics of humic substances from different environments as determined by size exclusion chromatography and their statistical evaluation. Environmental Science and Technology 37: 2477–2485.

    Article  CAS  Google Scholar 

  • Schepetkin, I.A., G. Xie, M.A. Jutila, and M.T. Quinn. 2009. Complement-fixing activity of fulvic acid from shilajit and other natural sources. Phytotherapy Research 23(3): 373–384.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Chemistry, Lomonosov Moscow State University, Leninskie gory, 1-3, Moscow, 119234, Russia

    A. I. Konstantinov, A. V. Kudryavtsev & I. V. Perminova

  2. Emanuel Institute for Biochemical Physics RAS, Kosygina ul., 4, Moscow, 119334, Russia

    G. N. Vladimirov & E. N. Nikolaev

  3. Institute for Energy Problems of Chemical Physics, Leninsky prosp., 38-2, Moscow, 119334, Russia

    G. N. Vladimirov & A. S. Grigoryev

Authors
  1. A. I. Konstantinov
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  2. G. N. Vladimirov
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  3. A. S. Grigoryev
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  4. A. V. Kudryavtsev
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  5. I. V. Perminova
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  6. E. N. Nikolaev
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Corresponding author

Correspondence to I. V. Perminova .

Editor information

Editors and Affiliations

  1. , Institute of Soil and Water Resources, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China, People's Republic

    Jianming Xu

  2. , College of Environmental & Resource Scie, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China, People's Republic

    Jianjun Wu

  3. , College of Environmental & Resource Scie, Zhejiang University, 866 Yuhangtang Road, Hangzhou, 310058, China, People's Republic

    Yan He

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© 2013 Zhejiang University Press and Springer Science+Business Media Dordrecht

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Konstantinov, A.I., Vladimirov, G.N., Grigoryev, A.S., Kudryavtsev, A.V., Perminova, I.V., Nikolaev, E.N. (2013). Molecular Composition Study of Mumijo from Different Geographic Areas Using Size-Exclusion Chromatography, NMR Spectroscopy, and High-Resolution Mass Spectrometry. In: Xu, J., Wu, J., He, Y. (eds) Functions of Natural Organic Matter in Changing Environment. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5634-2_52

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