Abstract
Cerebellar midline primitive neuroectodermal tumours containing muscle fibers generally referred to as medullomyoblastoma. Medullomyoblastoma is almost exclusively seen in children. The clinical findings are similar to the every midline posterior fossa tumour. Clinical history is typically brief, the prognosis is very poor. Medullomyoblastomas are seen as solid lesion on computerized tomography and magnetic resonance imaging. They enhance with intravenous contrast media on all imaging sequences. There are four main theories considering histogenesis of the muscle fibers within the tumour. It is accepted as a teratoma or a teratoid tumour widely. Surgical debulking is essential part of the treatment. Postoperative radiotherapy and chemotherapy may be beneficial for lengthening of the survival time. Pathologic examination generally shows two distinct patterns in different areas. Both malignant apparent striated and smooth muscle fibers can be found within the tumour. The documented myogenic differentiation is necessary for the definitive diagnosis.
An erratum to this chapter can be found at http://dx.doi.org/10.1007/978-94-007-4528-5_31
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© 2012 Springer Science+Business Media Dordrecht
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Er, U. (2012). Teratoid Pediatric Medullomyoblastoma. In: Hayat, M. (eds) Pediatric Cancer, Volume 3. Pediatric Cancer, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4528-5_9
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DOI: https://doi.org/10.1007/978-94-007-4528-5_9
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