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Detection of Anti-Allergic Factors in Strawberry Extracts

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Animal Cell Technology: Basic & Applied Aspects

Part of the book series: Animal Cell Technology: Basic & Applied Aspects ((ANICELLTECH,volume 16))

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Abstract

We examined the anti-allergic action of strawberry extracts in pollinosis by using an in vitro IgE inducing method. It was found that several kinds of the strawberries suppressed total IgE production as much as epicatechin gallate that is well known as an anti-allergic factor. The IgE decrease was correlated to the decrease of SOCS3 specifically expressed in Th2 cells that promote IgE production. In addition, Biacore analysis revealed that there is a factor with the ability to bind with the ceder pollen allergen Cryj1 in the strawberry extracts. These results suggest that the strawberry extracts may suppress the allergic reaction by acting on both Th2 cells and Cryj1 allergen.

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Author information

Authors and Affiliations

  1. Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Wakamatsu-ku, Kitakyushu-shi, Fukuoka, 808-0196, Japan

    Kazuhiro Mitsuda

  2. The Cell Engineering Center, Kitakyushu National College of Technology, Kitakyushu-shi, Fukuoka, 802-0985, Japan

    Aiko Inoue, Yuichi Inoue & Hiroharu Kawahara

  3. The Cell Engineering Center, Kitakyushu National College of Technology, Kokuraminami-ku, Kitakyushu, 802-0985, Japan

    Aiko Inoue & Yuichi Inoue

  4. Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Kitakyushu-shi, Fukuoka, 808-0196, Japan

    Norikazu Nishino

Authors
  1. Kazuhiro Mitsuda
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  2. Aiko Inoue
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  3. Norikazu Nishino
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  4. Yuichi Inoue
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  5. Hiroharu Kawahara
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Corresponding author

Correspondence to Kazuhiro Mitsuda .

Editor information

Editors and Affiliations

  1. Fac. Engineering, Dept. Chemical Engineering, Kyushu University, Motooka 744, Fukuoka, 819-0395, Japan

    Masamichi Kamihira

  2. Fac. Agriculture, Kyushu University, Hakozaki 6-10-1, Fukuoka, 812-8581, Japan

    Yoshinori Katakura

  3. Fac. Engineering, Kyushu University, Fukuoka, 819-0395, Japan

    Akira Ito

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Mitsuda, K., Inoue, A., Nishino, N., Inoue, Y., Kawahara, H. (2010). Detection of Anti-Allergic Factors in Strawberry Extracts. In: Kamihira, M., Katakura, Y., Ito, A. (eds) Animal Cell Technology: Basic & Applied Aspects. Animal Cell Technology: Basic & Applied Aspects, vol 16. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-3892-0_58

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