Abstract
Verslaving is een psychiatrische ziekte die met behulp van beeldvormingstechnieken in toenemende mate wordt bestudeerd. Nieuwe inzichten op dit terrein geven aan dat een herhaalde blootstelling aan alcohol en/of drugs leidt tot veranderingen in het brein waarbij hersencircuits op micro- en macroniveau progressief disfunctioneren. Om deze ontregelde neurobiologische processen te herstellen vormen symptoomcomplexen (syndromen) die kenmerkend zijn voor de stoornis, aangrijpingspunten voor een medicamenteuze behandeling in de forensische verslavingszorg. Conform een ‘functioneel psychofarmacologisch’ paradigma deze symptomen worden geclusterd in craving, impulsiviteit/compulsiviteit en ontremd gedrag. De huidige stand van zaken is dat er verschillende effectieve medicamenten beschikbaar zijn die ingezet kunnen worden in een breder behandelkader.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
Literatuur
Addolorato, G., Leggio, L., Abenavoli, L., Agabio, R., Caputo, F., Capristo, E., Colombo, G., Gessa, G. L. & Gasbarrini, G. (2006). Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam. American Journal of Medicine, 119 (3), 276.e13–8.
Addolorato, G. & Leggio, L. (2010). Safety and efficacy of baclofen in the treatment of alcohol-dependent patients. Current Pharmaceutical Design, 16 (19), 2113–2117.
Alexander, G.E. (1994). Basal ganglia-thalamocortical circuits: Their role in control of movements. Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society, 11 (4), 420–431.
Anton, R.F., Kranzler, H., Breder, C., Marcus, R.N., Carson, W.H. & Han, J. (2008). A randomized, multicenter, double-blind, placebo-controlled study of the efficacy and safety of aripiprazole for the treatment of alcohol dependence. Journal of Clinical Psychopharmacology, 28 (1), 5–12.
Anton, R.F., O’Malley, S.S., Ciraulo, D.A., Cisler, R.A., Couper, D., Donovan, D.M., Gastfriend, D.R., Hosking, J.D., Johnson, B.A., LoCastro, J.S., Longabaugh, R., Mason, B.J., Mattson, M.E., Miller, W.R., Pettinati, H.M., Randall, C.L., Swift, R., Weiss, R.D., Williams, L.D., & Zweben, A.; COMBINE Study Research Group. (2006). Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. Journal of the American Medical Association, 295 (17), 2003–2017.
Aouizerate, B., Guehl, D., Cuny, E., Rougier, A., Bioulac, B., Tignol, J. & Burbaud, P. (2004). Pathophysiology of obsessive-compulsive disorder: A necessary link between phenomenology, neuropsychology, imagery and physiology. Progress in Neurobiology, 72 (3), 195–221.
Bakker, J.B., Hovens, J.E. & Loonen, A.J.M. (2001). Soms is roken beter. Medisch Contact, 56, 1607–1609.
Berthel, T. (2003). Psychiatrische Komorbidität. In E. Beubler, H. Haltmayer & A. Springer (Eds.), Opiatabhängigkeit. Interdisciplinäre Aspekte für die Praxis. Vienna: Springer.
Bouza, C., Angeles, M., Munoz, A. & Amate, J.M. (2004). Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review. Addiction, 99, 811–828.
Brink, W. van den (2009). Farmacotherapie. In W. van den Brink & I. Franken (Red.), Handboek verslaving. Leusden: De Tijdstroom.
Bruinsma, F. & Loonen, A.J.M. (2006). Neurobiologie van cognitieve en emotionele motivatie. Neuropraxis, 7, 77–86.
Chambers, R.A. (2009). A Nicotine Challenge to the Self-Medication Hypothesis in a Neurodevelopmental Animal Model of Schizophrenia. Journal of Dual Diagnosis, 5 (2), 139–148.
Dalley, J.W., Mar, A.C., Economidou, D. & Robbins, T.W. (2008). Neurobehavioral mechanisms of impulsivity: Fronto-striatal systems and functional neurochemistry. Pharmacology, Biochemistry and Behavior, 90 (2), 250–260.
De Lima, M.S., de Oliveira Soares, B.G., Reisser, A.A., Farrell, M. (2002). Pharmacological treatment of cocaine dependence: a systematic review. Addiction, 97 (8), 931–949.
Dijkstra, B.A.G., Jong, C.A.J. de, Bluschke, S.M., Krabbe, P.F.M. & Staak, C.P.F. van der (2007). Does naltrexone affect craving in abstinent opioid dependent patients? Addiction Biology, 12, 176–182.
Engel, G.L. (1980). The clinical application of the biopsychosocial model. American Journal of Psychiatry, 137, 534–544.
Galyuk, T.M., Backer, G. de, Jong, C.A.J. de & Loonen, A.J.M. (2009). Misbruik van quetiapine. Twee verslaafde patiënten met een borderline persoonlijkheidsstoornis. Nederlands Tijdschrift voor Geneeskunde, 153, 674–677.
George, T.P. & Krystal, J.H. (2000), Comorbidity of psychiatric and substance abuse disorders. Current Opinion in Psychiatry, 13 (3), 327–331.
Glind, G. van de, Eland, A. & Janssen, M. (2001). ADHD en verslaving: Een literatuuronderzoek naar de samenhang tussen ADHD en verslavingsproblemen. Maandblad Geestelijke volksgezondheid, 56 (6), 437–555.
Groenewegen, H.J. (2007). The ventral striatum as an interface between the limbic and motor systems. CNS Spectrums, 12 (12), 887–892.
Ingenhoven, T. & Rinne, T. (2007). In Landelijke Stuurgroep Multidisciplinaire Richtlijnontwikkeling in de GGZ, Multidisciplinaire Richtlijn Persoonlijkheidsstoornissen 2008 (p. 174). Utrecht: Trimbos-instituut.
Johnson, B.A., Ait-Daoud, N., Akhtar, F.Z. & Ma, J.Z. (2004). Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals. Archives of General Psychiatry, 61, 905–912.
Johnson, B.A., Ait-Daoud, N., Seneviratne, C., Roache, J.D., Javors, M.A., Wang, X.Q., Liu, L., Penberthy, J.K., DiClemente, C.C. & Li, M.D. (2011). Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinking. American Journal of Psychiatry, 168 (3), 265–275.
Johnson, B.A. & Ait-Daoud, N. (2010). Topiramate in the new generation of drugs: efficacy in the treatment of alcoholic patients. Current Pharmaceutical Design, 16 (19), 2103–2112.
Johnson, B.A. (2010). Medication treatment of different types of alcoholism. American Journal of Psychiatry, 167 (6), 630–639.
Kelly, T.M., Daley, D.C. & Douaihy, A.B. (2012). Treatment of substance abusing patients with comorbid psychiatric disorders. Addictive Behaviors, 37 (1), 11–24.
Lange, T.H., Brink, W. van den, & Hanneman P.J.J. (2005). Antipsychotica bij patiënten met een dubbeldiagnose schizofrenie en middelenmisbruik. Een literatuuroverzicht. Tijdschrift voor Psychiatrie, 47 (4), 219–228.
Liappas, J. (2001). Drug addiction: a multidimensional therapeutic problem. Itaca, 6 (s), 9–22.
Loonen, A.J.M. (2011). A comparison of the neurobiology underlying psychiatric and extrapyramidal movement disorders. (aangeboden voor publicatie)
Loonen, A.J.M. & Hovens, J.E. (Red.) (2012). Handboek functionele psychofarmacologie. Utrecht: De Tijdstroom.
Loonen, A.J.M. & Stahl, S.M. (2010). Functional psychopharmacology is the way to go in pharmacotherapy for psychiatric disorders. Acta Psychiatrica Scandinavica, 122, 435–437.
Machielsen, M., Scheltema Beduin, A., Dekker, N., Kahn, R.S., Linszen, D.H., Os J. van, Wiersma, D., Bruggeman, R., Cahn, W., Haan, L. de, Krabbendam, L. & Myin-Germeys, I. (in druk). Differences in craving for cannabis between schizophrenia patients using risperidone, olanzapine or clozapine. Journal of Psychopharmacology.
Mann, K., Lehert, P. & Morgan, M.Y. (2004). The efficacy of acamprosate in the maintenance of abstinence in alcohol-dependent individuals: results of a meta-analysis. Alcoholism: Clinical & Experimental Research, 28, 51–63.
Martínez-Raga, J., Knecht, C. & Cepeda, S. (2008). Modafinil: a useful medication for cocaine addiction? Review of the evidence from neuropharmacological, experimental and clinical studies. Current Drug Abuse Reviews, 1 (2), 213–221.
Mason, B.J., Goodman, A.M., Chabac, S. & Lehert, P. (2006). Effect of oral acamprosate on abstinence in patients with alcohol dependence in a double-blind, placebocontrolled trial: the role of patient motivation. Journal of Psychiatric Research, 40, 383–393.
Mason, B.J., Salvato, F.R., Williams, L.D., Ritvo, E.C. & Cutler, R.B. (1999). A doubleblind, placebo-controlled study of oral nalmefene for alcohol dependence. Archives of General Psychiatry, 56 (8), 719–724.
Mattick, R.P., Digiusto E., Doran, C.M., O’Brien, S., Shanahan, M., Kimber, J., Henderson, N., Breen, C., Shearer, J., Gates, J., Shakeshaft, A. & NEPOD Trial Investigators (2001). National Evaluation of Pharmacotherapies for Opioid Dependence: Report of Results and Recommendations. Sydney, Australia: National Drug and Alcohol Research Centre. Publication Approval number 3452 (JN 8514).
McEvoy, J.P., Freudenreich, O., Levin, E.D. & Rose, J.E. (1995). Haloperidol increases smoking in patients with schizophrenia. Psychopharmacology, 119, 124–126.
Moeller, F.G., Barratt, E.S., Dougherty, D.M., Schmitz, J.M. & Swann, A.C. (2001). Psychiatric aspects of impulsivity. American Journal of Psychiatry, 158, 1783–1793.
Mueser, K.T., Drake, R.E. & Wallach, M.A. (1998). Dual diagnosis: a review of etiological theories. Addictive behaviors, 23 (6), 717–734.
National Institute on Drug Abuse (2009). Principles of drug addiction treatment: A researchbased guide (2 nd edition). Betesda, MD: NIDA.
Nestler, E.J. (2001). Molecular basis of long-term plasticity underlying addiction. Nature Reviews Neuroscience, 2 (2), 119–128.
NIFP (2010). Formularium NIFP en PPC. Psychofarmacotherapie in het gevangeniswezen (versie 2010). Amsterdam: SSP.
O’Brien, C.P. & McLellan, A.T. (1996). Myths about the treatment of addiction. Lancet, 347 (8996), 237–240.
Praag, H.M. van (2000). Psychofarmaca. Assen: Van Gorcum.
Kwaliteitsinstituut voor de Gezondheidszorg CBO (2008). Richtlijn ‘Medicamenteuze zorg aan gedetineerde verslaafden’. Den Haag: Dienst Justitiële Inrichtingen.
Rooijen, M. van (2001). Dubbele-diagnosekliniek: zendingswerk. Psy, 14, 24–29.
Roozen, H.G., Waart, R. de, Windt, D.A.W.N. van der, Brink, W. van den, Jong, C.A.J. de & Kerkhof, A.J.F.M. (2006). A systematic review of the effectiveness of naltrexone in the treatment of opioid and alcohol dependence. European Neuropsychopharmacology, 16 (5), 311–323.
Roozen, H.G., Kroon, H., Pree-van der Slik, A. du & Wetering, B.J.M. van de (2009). Ambulante behandeling van chronisch verslaafden. In W. van den Brink & I. Franken (Red.), Handboek verslaving. Leusden: De Tijdstroom.
Rösner, S., Hackl-Herrwerth, A., Leucht, S., Vecchi, S., Srisurapanont, M. & Soyka, M. (2010). Opioid antagonists for alcohol dependence. Cochrane Database Syst Rev 8 (12), CD001867.
Schadé, A., Marquenie, L.A., Balkom, A.J. van, Koeter, M.W., Beurs, E. de, Brink, W. van den & Dyck, R. van (2005). The effectiveness of anxiety treatment on alcoholdependent patients with a comorbid phobic disorder: a randomized controlled trial. Alcoholism: Clinical & Experimental Research, 29 (5), 794–800.
Schroeder, J.P., Cooper, D.A., Schank, J.R., Lyle, M.A., Gaval-Cruz, M., Ogbonmwan, Y.E., Pozdeyev, N., Freeman, K.G., Iuvone, P.M., Edwards, G.L., Holmes, P.V. & Weinshenker, D. (2010). Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β -hydroxylase. Neuropsychopharmacology, 35 (12), 2440–2449.
Srisurapanont, M. & Jarusuraisin, N. (2004). Opioid antagonists for alcohol dependence (Cochrane Review). In The Cochrane Library, 1, Oxford: Update Software.
Stel, J. van der (2009). Comorbiditeit. In W. van den Brink & I. Franken (Red.), Handboek verslaving. Leusden: De Tijdstroom.
Voronin, K., Randall, P., Myrick, H. & Anton, R. (2008). Aripiprazole effects on alcohol consumption and subjective reports in a clinical laboratory paradigm – possible influence of self-control. Alcoholism: Clinical & Experimental Research, 32 (11), 1954–1961.
Waarde, A. van, Vaalburg, W., Doze, P., Bosker, F.J. & Elsinga, P.H. (2004). PET imaging of beta-adrenoceptors in human brain: A realistic goal or a mirage? Current Pharmaceutical Design, 10 (13), 1519–1536.
Editor information
Copyright information
© 2012 Bohn Stafleu van Loghum
About this chapter
Cite this chapter
van Marle, H., Loonen, A., Roozen, H. (2012). Behandeling met medicatie. In: Blaauw, E., Roozen, H. (eds) Handboek forensische verslavingszorg. Bohn Stafleu van Loghum, Houten. https://doi.org/10.1007/978-90-313-8851-6_13
Download citation
DOI: https://doi.org/10.1007/978-90-313-8851-6_13
Publisher Name: Bohn Stafleu van Loghum, Houten
Print ISBN: 978-90-313-8850-9
Online ISBN: 978-90-313-8851-6
eBook Packages: Dutch language eBook collection