Skip to main content

Electroconvulsive Therapy: Research from India

  • Chapter
  • First Online:
Developments in Psychiatry in India
  • 660 Accesses

Abstract

Electroconvulsive therapy (ECT) has been one of the most controversial treatment methods in psychiatry for past several decades. Since its inception in 1938, the practice of ECT has undergone quite a few improvements, including use of modified treatments and brief-pulse methods of administration. Though there is considerable variation in the rates and practice of administration of ECT worldwide, evidence has shown that it is a safe and effective treatment when used properly. ECT is primarily used for treatment of depression, less often for schizophrenia and mania. It is mostly used in very severe, treatment-resistant states. ECT is used quite frequently in developing countries. Research from India has established the efficacy of ECT in depression, schizophrenia, catatonia and mania. The practice of ECT has also been extensively investigated, as have the mechanisms underlying its effect. There is also some literature on the awareness and perceptions of patients and family members concerning the treatment. Ethical and legal aspects of administering the treatment have been widely debated as well.

K. Deka, Professor; S. Balachander, Junior Resident

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Abraham, K. R., & Kulhara, P. (1987). The efficacy of electroconvulsive therapy in the treatment of schizophrenia. A comparative study. BJP, 151, 152–155.

    CAS  Google Scholar 

  • American Psychiatric Association, Committee on Electroconvulsive Therapy, Weiner R. D. (2001). The Practice of Electroconvulsive therapy: Recommendations for Treatment, Training and Privileging: A task force report of the American Psychiatric Association, 2nd Edition, Washington DC: American Psychiatric Association.

    Google Scholar 

  • Andrade, C. (1992). The practice of electroconvulsive therapy in India: Considerable room for improvement. Editorial. Indian Journal of Psychology Medicine, 15, 14.

    Google Scholar 

  • Andrade, C. (1993). Seizure duration and related issues in ECT for endogenous depression. Indian Journal of Psychiatry, 35, 43–47.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Andrade, C. (2010). Variations on a theme of unmodified ECT: Science or heresy? The Journal of ECT, 26, 30–31.

    Article  PubMed  Google Scholar 

  • Andrade, C., Rele, K., Sutharshan, R., & Shah, N. (2000). Musculoskeletal morbidity with unmodified ect may be less than earlier believed. Indian Journal of Psychiatry, 42, 156–162.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Andrade, C., Gangadhar, B. N., Subbakrishna, D. K., Channabasavanna, S. M., & Pradhan, N. (1988). A Double-Blind Comparison of Sinusoidal Wave and Brief-Pulse Electroconvulsive Therapy in Endogenous Depression. Convulsive Therapy, 4(4). http://journals.lww.com/ectjournal/toc/1988/04040

  • Bharadwaj, V., Grover, S., Chakrabarti, S., Avasthi, A., & Kate, N. (2012). Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy: a study from north India. Indian Journal of Psychiatry, 54, 41–47.

    Article  PubMed Central  PubMed  Google Scholar 

  • Chakrabarti, S., Grover, S., & Rajagopal, R. (2010a). Electroconvulsive therapy: A review of knowledge, experience and attitudes of patients concerning the treatment. World Journal of Biological Psychiatry, 11, 525–537.

    Article  PubMed  Google Scholar 

  • Chakrabarti, S., Grover, S., & Rajagopal, R. (2010b). Perceptions and awareness of electroconvulsive therapy among patients and their families: a review of the research from developing countries. The Journal of ECT, 26, 317–322.

    Article  PubMed  Google Scholar 

  • Chanpattana, W., Kramer, B. A., Kunigiri, G., Gangadhar, B. N., Kitphati, R., & Andrade, C. (2010). A survey of the practice of electroconvulsive therapy in Asia. Journal of ECT, 26, 5–10.

    Article  PubMed  Google Scholar 

  • Chanpattana, W., Kunigiri, G., Kramer, B. A., & Gangadhar, B. N. (2005). Survey of the practice of electroconvulsive therapy in teaching hospitals in India. Journal of ECT, 21, 100–104.

    Article  PubMed  Google Scholar 

  • Chopra, V. K., & Sinha, V. K. (2002). ECT in mentally retarded subjects with psychiatric illness. Indian Journal of Psychiatry, 44, 57–64.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Dalal, P. K., Lal, N., Trivedi, J. K., Seth, P. K., Agarwal, A. K., & Khalid, A. (1998). Active platelet 5-HT uptake in major depression. Indian Journal of Psychiatry, 40, 60–66.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Gangadhar, B. N., Choudhary, R. J., & Channabasavanna, S. M. (1983). ECT and drug induced Parkinsonism. Indian Journal of Psychiatry, 25, 212–213.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Gangadhar, B. N., Phutane, V. H., & Thirthalli, J. (2010). Research on electroconvulsive therapy in India: An overview. Indian Journal of Psychiatry, 52, S362–S365.

    Article  PubMed Central  PubMed  Google Scholar 

  • Gangadhar, B. N., Ramadevi, G., Andrade, C., & Pradhan, N. (1990). Single electroconvulsive shock and dopamine autoreceptors. Indian Journal of Psychiatry, 32, 302–304.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Gangadhar, B. N., Subbakrishna, D. K., Janakiramaiah, N., Motreja, S., NarayanaDutt, D., & Paramehwara, G. (1999). Post-seizure EEG fractal dimension of first ECT predicts antidepressant response at two weeks. Journal of Affective Disorders, 52, 235–238.

    Article  CAS  PubMed  Google Scholar 

  • Gangadhar, B. N., & Thirthalli, J. (2010). Frequency of electroconvulsive therapy sessions in a course. Journal of ECT, 26, 181–185.

    Article  PubMed  Google Scholar 

  • Gangadhar et. al. (2003). Seizure asymmetry with greater amplitude on the stimulated side in unilateral ECT. Paper presented at the 51st Annual National Conference of Indian Psychiatric Society, India:Hyderabad.

    Google Scholar 

  • Ghaziuddin, N., Kutcher, S., & Knapp, P. (2004). Practice parameter for use of electroconvulsive therapy with adolescents. Journal of American Academy of Child and Adolescent Psychiatry, 43, 1521–1539.

    Article  Google Scholar 

  • Gill, N. S., Girish, K., & Gangadhar, B. N. (2002). Ictal RPP—A supplement to cuff method in detecting ect-induced cerebral seizure. Indian Journal of Psychiatry, 44, 29–33.

    PubMed Central  PubMed  Google Scholar 

  • Girish, K., & Gill, N. S. (2003). Electroconvulsive therapy in lorazepam non-responsive catatonia. Indian Journal of Psychiatry, 45, 21–25.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Girish, K., Jayakumar, P. N., Murali, N., Gangadhar, B. N., Janakiramaiah, N., & Subbakrishna, D. K. (2001). ECT and T2 relaxometry: A static walter proton magnetic resonance imaging study. Indian Journal of Psychiatry, 43, 22–24.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Goswami, U., Kumar, U., & Singh, B. (2003). Efficacy of electroconvulsive therapy in treatment resistant schizophreinia: A double-blind study. Indian Journal of Psychiatry, 45, 26–29.

    PubMed Central  PubMed  Google Scholar 

  • Goswami, U., Sunil, D., Kuruvilla, K., Eva Papp, Andras, P. (1989). Electroconvulsive therapy in neuroleptic-induced parkinsonism. Biological Psychiatry, 26(3), 234–238. http://www.biologicalpsychiatryjournal.com/issue/S0006-3223(00)X0372-1

  • Grover, S., Chakrabarti, S., Khehra, N., et al. (2011). Does the experience of electroconvulsive therapy improve awareness and perceptions of treatment among relatives of patients? Journal of ECT, 27, 67–72.

    Article  PubMed  Google Scholar 

  • Grover, S., Malhotra, S., Varma, S., Chakrabarti, S., Avasthi, A., & Mattoo, S. K. (2013). Electroconvulsive therapy in adolescents: A retrospective study from north india. Journal of ECT, 29(2), 122–126. http://journals.lww.com/ectjournal/toc/2013/06000

  • Gupta, S., Tobiansky, R., Bassett, P., & Warner, J. (2008). Efficacy of Maintenance Electroconvulsive Therapy in recurrent depression: A naturalistic study. Journal of ECT, 24 (3), 191–194.

    Google Scholar 

  • Gupta, N., Avasthi, A., & Kulhara, P. (2000). Clinical variables as predictors of response to electroconvulsive therapy in endogenous depression. Indian Journal of Psychiatry, 42, 60–65.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Hiremani, R. M., Thirthalli, J., Tharayil, B. S., & Gangadhar, B. N. (2008). Double-blind randomized controlled study comparing short-term efficacy of bifrontal and bitemporal electroconvulsive therapy in acute mania. Bipolar Disorders, 10, 701–707.

    Article  PubMed  Google Scholar 

  • Jain, G., Kumar, V., Chakrabarti, S., & Grover, S. (2008). The use of electroconvulsive therapy in the elderly: a study from the psychiatric unit of a north Indian teaching hospital. Journal of ECT, 24, 122–127.

    Article  PubMed  Google Scholar 

  • Jain, G., Kumar, V., Chakrabarti, S., & Grover, S. (2007). Use of electroconvulsive treatment in elderly: A clinical audit. Indian Journal of Psychiatry, 49, 31.

    Google Scholar 

  • Janakiramaiah, N., JyotiRao, K. M., Praveen, J., Sujatha, L., Gangadhar, B. N., & Subbakrishna, D. K. (1992). Seizure duration over ECT sessions: Influence of spacing ECTs. Indian Journal of Psychiatry, 34, 124–127.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Leiknes, K. A., Schweder, L. J. V., Høie, B., & 283. (2012). Contemporary use and practice of electroconvulsive therapy worldwide. Brain Behavior, 2(3), 283–344.

    Article  PubMed Central  PubMed  Google Scholar 

  • Mukherjee, S., Sackeim, H. A., & Schnur, F. B. (1994). Electroconvulsive therapy of acute manic episodes: A review of 50 years' experience. American Journal of Psychiatry, 151, 169–176.

    Google Scholar 

  • Muralidharan, K., Thimmaiah, R., Chakraborty, V., & Jain, S. (2011). Bifrontal ECT for drug-induced psychosis in Parkinson’s disease. Indian Journal of Psychiatry, 53, 156–158.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Painuly, N., & Chakrabarti, S. (2006). Combined use of electroconvulsive therapy and antipsychotics in schizophrenia: the Indian evidence. A review and a meta-analysis. Journal of ECT, 22, 59–66.

    Article  PubMed  Google Scholar 

  • Phutane, V. H., Thirthalli, J., Kesavan, M., Kumar, N. C., Gangadhar, B. N., & 149. (2011). Why do we prescribe ECT to schizophrenia patients? Indian Journal of Psychiatry, 53, 149–151.

    Article  PubMed Central  PubMed  Google Scholar 

  • Rajagopal, R., Chakrabarti, S., & Grover, S. (2013). Satisfaction with electroconvulsive therapy among patients and their relatives. Journal of ECT, 29(4), 279–286. (Epub ahead of print).

    Article  Google Scholar 

  • Rajagopal, R., Chakrabarti, S., Grover, S., & Khehra, N. (2012). Knowledge, experience & attitudes concerning electroconvulsive therapy among patients & their relatives. Indian Journal of Medical Research, 135, 201–210.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Sackeim, H.A. (1989 Review). In The Practice of Electroconvulsive Therapy: Recommendations for Treatment, Training and Privileging(2nd Edn.). American Psychiatric Association

    Google Scholar 

  • Saravanan, E. S., Gangadhar, B. N., Janakiramaiah, N., Pandey, R. S., Murthy, H. S., & Subbakrishna, D. K. (2002). Does higher cardiovascular response to ECT predict early antidepressant effect? Journal of Affective Disorders, 69, 101–108.

    Article  CAS  PubMed  Google Scholar 

  • Scott, A. I. F. (2005). The ECT Handbook (2nd Edn). London: Royal College of Psychiatrists.

    Google Scholar 

  • Sikdar, S., Kulhara, P., Avasthi, A., & Singh, H. (1994). Combined chlorpromazine and electroconvulsive therapy in mania. British Journal of Psychiatry, 164, 806–810.

    Article  CAS  PubMed  Google Scholar 

  • Srinivasan, T. N., Suresh, T. R., & Jayaram, V. (1995). Issues in the use of maintenance electroconvulsive therapy. Indian Journal of Psychiatry, 37, 139–142.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Thakur, A., Dutta, S., Jagadheesan, K., & Sinha, V. K. (2001). Electroconvulsive therapy in pre-pubertal catatonia: A case study. Indian Journal of Psychiatry, 43, 354–356.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Tharyan, P., & Adams, C. E. (2005). Electroconvulsive therapy for schizophrenia. Cochrane Database Systematic Reviews. 18: CD000076.

    Google Scholar 

  • Thippeswamy, H., Goswami, K., & Chaturvedi, S. (2012). Ethical aspects of public health legislation: The mental health care bill, 2011. Indian Journal of Medical Ethics, 9, 46–49.

    PubMed  Google Scholar 

  • Thirthalli, J., Kumar, C. N., Bangalore, R. P., & Gangadhar, B. N. (2009). Speed of response to threshold and suprathreshold bilateral ECT in depression, mania and schizophrenia. Journal of Affective Disorders, 117, 104–107.

    Article  PubMed  Google Scholar 

  • Viswanath, B., Narayanaswamy, J. C., Thirthalli, J., & Gangadhar, B. N. (2011). Effectiveness of bifrontal ECT in practice: A comparison with bitemporal ECT. Indian Journal of Psychological Medicine, 33, 66–70.

    Article  PubMed Central  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. Deka .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer India

About this chapter

Cite this chapter

Deka, K., Balachander, S. (2015). Electroconvulsive Therapy: Research from India. In: Malhotra, S., Chakrabarti, S. (eds) Developments in Psychiatry in India. Springer, New Delhi. https://doi.org/10.1007/978-81-322-1674-2_27

Download citation

  • DOI: https://doi.org/10.1007/978-81-322-1674-2_27

  • Published:

  • Publisher Name: Springer, New Delhi

  • Print ISBN: 978-81-322-1673-5

  • Online ISBN: 978-81-322-1674-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics