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Bartonellosis: A One Health Perspective

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Confronting Emerging Zoonoses

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Abstract

Recently, Bartonella, a genus comprised of fastidious, Gram-negative, intracellular bacteria, has rapidly expanded from approximately 4–5 species in the 1990s to 30–40 named or proposed species that are currently described in the literature. While Bartonellae are highly adapted to a number of mammalian reservoir hosts, substantial genetic diversity allows for the transmission of Bartonella to humans (i.e. a zoonosis) and other non-reservoir hosts. Improvements in the diagnostic sensitivity of laboratory tests have allowed researchers to identify a spectrum of Bartonella species in novel host species, including domestic animals and wildlife. Because Bartonella can infect a spectrum of accidental hosts, it is imperative that researchers determine the consequences of Bartonella spp. infection on new host populations and the impact of this genus during environmental changes, particularly natural disasters. Rapid, accurate diagnostic tests now afford researchers and clinicians the ability to conduct more reliable epidemiologic and treatment related studies that will better characterize the outcomes of Bartonella spp. infection in animals and human patients. Prevalence studies have shown that Bartonella spp. DNA can be found in numerous arthropods, though additional research is required to identify epidemiologically important competent vectors of Bartonella spp. transmission. Future Bartonella spp. research initiatives should strive to not only identify the bacterium in arthropod and host populations, but also to combine those data with epidemiologically relevant case data and ecological risk assessment. Combined efforts from professionals in animal and human medicine, vector ecology, pathogen evolution, microbial ecology, and sociology are necessary in order to create the veterinary and medical infrastructure, training, prevention, and surveillance required to thoroughly understand Bartonella spp. ecology, dynamics and control. Bartonellosis may prove to be one of the most important One Health emerging zoonotic diseases of the next decade.

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Notes

  1. 1.

    Bartonella species that are able to infect rodents and small mammals include B. elizabethae (Ying et al. 2002), B. grahamii (Ellis et al. 1999), B. vinsonii subsp. arupensis (Welch et al. 1999), B. doshiae (Birtles et al. 1995), B. taylorii (Birtles 1995), B. vinsonii subsp. vinsonii (Ellis et al. 1999), B. tribocorum (Heller et al. 1998), B. washoensis (Kosoy et al. 2003), B. rattimassiliensis (Gundi et al. 2004), B. phoceensis (Gundi et al. 2004), B. birtlesii (Bermond et al. 2000), B. rochalimae (Lin et al. 2008), B. japonica (Inoue et al. 2010), and B. silvatica (Inoue et al. 2010).

  2. 2.

    Studies have documented seroprevalences in cats of 47 % in Hawaii, 15 % in Japan, 40.6 % and 41.8 % in pet and feral cats in the United Kingdom, respectively, 54 % in Indonesia, 53 % in France, 40 % in Israel, 11 % in Egypt, 7 % in Portugal, 48 % in Singapore, 21 % in South Africa, and 24 % in Zimbabwe (Kelly et al. 1996; Nasirudeen and Thong 1999; Childs et al. 1995; Maruyama et al. 1996; Demers et al. 1995; Barnes et al. 2000)

  3. 3.

    Including B. vinsonii subsp. berkhoffii, B. henselae, B. vinsonii subsp. arupensis, B. clarridgeiae, B. washoensis, B. elizabethae, B. quintana, B. koehlerae, B. bovis, B. rochalimae.

References

  • Adelson ME, Rao RV, Tilton RC, Cabets K, Eskow E, Fein L, Occi JL, Mordechai E (2004) Prevalence of Borrelia burgdorferi, Bartonella spp., Babesia microti, and Anaplasma phagocytophila in Ixodes scapularis ticks collected in Northern New Jersey. J Clin Microbiol 42(6):2799–2801. doi:10.1128/JCM.42.6.2799-2801.2004

    PubMed Central  PubMed  Google Scholar 

  • Alcantara V, Rolain JM, Eduardo AG, Raul MJ, Raoult D (2009) Molecular detection of Bartonella quintana in human body lice from Mexico City. Clin Microbiol Infect 15(Suppl 2):93–94. doi:10.1111/j.1469-0691.2008.02176.x

    PubMed  Google Scholar 

  • Angelakis E, Pulcini C, Waton J, Imbert P, Socolovschi C, Edouard S, Dellamonica P, Raoult D (2010) Scalp eschar and neck lymphadenopathy caused by Bartonella henselae after Tick Bite. Clin Infect Dis 50(4):549–551. doi:10.1086/650172

    PubMed  Google Scholar 

  • Armengol CE, Hendley JO (1999) Cat-scratch disease encephalopathy: a cause of status epilepticus in school-aged children. J Pediatr 134(5):635–638

    CAS  PubMed  Google Scholar 

  • Avidor B, Graidy M, Efrat G, Leibowitz C, Shapira G, Schattner A, Zimhony O, Giladi M (2004) Bartonella koehlerae, a new cat-associated agent of culture-negative human endocarditis. J Clin Microbiol 42(8):3462–3468. doi:10.1128/JCM.42.8.3462-3468.2004

    CAS  PubMed Central  PubMed  Google Scholar 

  • Bai Y, Kosoy MY, Ray C, Brinkerhoff RJ, Collinge SK (2008) Temporal and spatial patterns of Bartonella infection in black-tailed prairie dogs (Cynomys ludovicianus). Microb Ecol 56(2):373–382. doi:10.1007/s00248-007-9355-6

    PubMed  Google Scholar 

  • Bai Y, Kosoy M, Recuenco S, Alvarez D, Moran D, Turmelle A, Ellison J, Garcia DL, Estevez A, Lindblade K, Rupprecht C (2011) Bartonella spp. in bats, Guatemala. Emerg Infect Dis 17(7):1269–1272. doi:10.3201/eid1707.101867

    PubMed Central  PubMed  Google Scholar 

  • Bai Y, Recuenco S, Gilbert AT, Osikowicz LM, Gomez J, Rupprecht C, Kosoy MY (2012) Prevalence and diversity of Bartonella spp. in bats in Peru. Am J Trop Med Hyg 87(3):518–523. doi:10.4269/ajtmh.2012.12-0097

    PubMed Central  PubMed  Google Scholar 

  • Barnes A, Bell SC, Isherwood DR, Bennett M, Carter SD (2000) Evidence of Bartonella henselae infection in cats and dogs in the United Kingdom. Vet Rec 147(24):673–677

    CAS  PubMed  Google Scholar 

  • Barnett H (1962) The incrimination of arthropods as vectors of disease. In: Proceedings of the 11th congress on entomology. Vienna, Austria

    Google Scholar 

  • Beard AW, Maggi RG, Kennedy-Stoskopf S, Cherry NA, Sandfoss MR, DePerno CS, Breitschwerdt EB (2011) Bartonella spp. in feral pigs, southeastern United States. Emerg Infect Dis 17(5):893–895. doi:10.3201/eid1705.100141

    PubMed Central  PubMed  Google Scholar 

  • Bermond D, Heller R, Barrat F, Delacour G, Dehio C, Alliot A, Monteil H, Chomel B, Boulouis HJ, Piemont Y (2000) Bartonella birtlesii sp. nov., isolated from small mammals (Apodemus spp.). Int J Syst Evol Microbiol 50(Pt 6):1973–1979

    PubMed  Google Scholar 

  • Bermond D, Boulouis HJ, Heller R, Van Laere G, Monteil H, Chomel BB, Sander A, Dehio C, Piemont Y (2002) Bartonella bovis Bermond et al. sp. nov. and Bartonella capreoli sp. nov., isolated from European ruminants. Int J Syst Evol Microbiol 52(Pt 2):383–390

    CAS  PubMed  Google Scholar 

  • Billeter SA, Levy MG, Chomel BB, Breitschwerdt EB (2008) Vector transmission of Bartonella species with emphasis on the potential for tick transmission. Med Vet Entomol 22(1):1–15. doi:10.1111/j.1365-2915.2008.00713.x

    CAS  PubMed  Google Scholar 

  • Billeter SA, Diniz PP, Battisti JM, Munderloh UG, Breitschwerdt EB, Levy MG (2009) Infection and replication of Bartonella species within a tick cell line. Exp Appl Acarol 49(3):193–208. doi:10.1007/s10493-009-9255-1

    PubMed  Google Scholar 

  • Billeter SA, Kasten RW, Killmaster LF, Breitschwerdt EB, Levin ML, Levy MG, Kosoy MY, Chomel BB (2012) Experimental infection by capillary tube feeding of Rhipicephalus sanguineus with Bartonella vinsonii subspecies berkhoffii. Comp Immunol Microbiol Infect Dis 35(1):9–15. doi:10.1016/j.cimid.2011.09.004

    PubMed  Google Scholar 

  • Birtles RJ (1995) Differentiation of Bartonella species using restriction endonuclease analysis of PCR-amplified 16S rRNA genes. FEMS Microbiol Lett 129(2–3):261–265

    CAS  PubMed  Google Scholar 

  • Birtles RJ, Harrison TG, Saunders NA, Molyneux DH (1995) Proposals to unify the genera Grahamella and Bartonella, with descriptions of Bartonella talpae comb. nov., Bartonella peromysci comb. nov., and three new species, Bartonella grahamii sp. nov., Bartonella taylorii sp. nov., and Bartonella doshiae sp. nov. Int J Syst Bacteriol 45(1):1–8

    CAS  PubMed  Google Scholar 

  • Birtles RJ, Hazel SM, Bennett M, Bown K, Raoult D, Begon M (2001) Longitudinal monitoring of the dynamics of infections due to Bartonella species in UK woodland rodents. Epidemiol Infect 126(2):323–329

    CAS  PubMed Central  PubMed  Google Scholar 

  • Bonatti H, Mendez J, Guerrero I, Krishna M, Ananda-Michel J, Yao J, Steers JL, Hellinger W, Dickson RC, Alvarez S (2006) Disseminated Bartonella infection following liver transplantation. Transpl Int 19(8):683–687. doi:10.1111/j.1432-2277.2006.00336.x

    PubMed  Google Scholar 

  • Bonilla DL, Kabeya H, Henn J, Kramer VL, Kosoy MY (2009) Bartonella quintana in body lice and head lice from homeless persons, San Francisco, California, USA. Emerg Infect Dis 15(6):912–915. doi:10.3201/eid1506.090054

    PubMed Central  PubMed  Google Scholar 

  • Bouchouicha R, Durand B, Monteil M, Chomel BB, Berrich M, Arvand M, Birtles RJ, Breitschwerdt EB, Koehler JE, Maggi R, Maruyama S, Kasten R, Petit E, Boulouis HJ, Haddad N (2009) Molecular epidemiology of feline and human Bartonella henselae isolates. Emerg Infect Dis 15(5):813–816. doi:10.3201/eid1505.080995

    CAS  PubMed Central  PubMed  Google Scholar 

  • Boulouis HJ, Chang CC, Henn JB, Kasten RW, Chomel BB (2005) Factors associated with the rapid emergence of zoonotic Bartonella infections. Vet Res 36(3):383–410. doi:10.1051/vetres:2005009

    PubMed  Google Scholar 

  • Bown KJ, Bennet M, Begon M (2004) Flea-borne Bartonella grahamii and Bartonella taylorii in bank voles. Emerg Infect Dis 10(4):684–687. doi:10.3201/eid1004.030455

    PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Kordick DL (2000) Bartonella infection in animals: carriership, reservoir potential, pathogenicity, and zoonotic potential for human infection. Clin Microbiol Rev 13(3):428–438

    CAS  PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Atkins CE, Brown TT, Kordick DL, Snyder PS (1999) Bartonella vinsonii subsp. berkhoffii and related members of the alpha subdivision of the Proteobacteria in dogs with cardiac arrhythmias, endocarditis, or myocarditis. J Clin Microbiol 37(11):3618–3626

    CAS  PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Blann KR, Stebbins ME, Munana KR, Davidson MG, Jackson HA, Willard MD (2004) Clinicopathological abnormalities and treatment response in 24 dogs seroreactive to Bartonella vinsonii (berkhoffii) antigens. J Am Anim Hosp Assoc 40(2):92–101

    PubMed  Google Scholar 

  • Breitschwerdt EB, Hegarty BC, Maggi R, Hawkins E, Dyer P (2005) Bartonella species as a potential cause of epistaxis in dogs. J Clin Microbiol 43(5):2529–2533. doi:10.1128/jcm.43.5.2529-2533.2005

    PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Maggi RG, Duncan AW, Nicholson WL, Hegarty BC, Woods CW (2007a) Bartonella species in blood of immunocompetent persons with animal and arthropod contact. Emerg Infect Dis 13(6):938–941

    PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Maggi RG, Sigmon B, Nicholson WL (2007b) Isolation of Bartonella quintana from a woman and a cat following putative bite transmission. J Clin Microbiol 45(1):270–272. doi:10.1128/jcm.01451-06

    CAS  PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Maggi RG, Nicholson WL, Cherry NA, Woods CW (2008) Bartonella sp. bacteremia in patients with neurological and neurocognitive dysfunction. J Clin Microbiol 46(9):2856–2861. doi:10.1128/JCM.00832-08

    CAS  PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Maggi RG, Varanat M, Linder KE, Weinberg G (2009) Isolation of Bartonella vinsonii subsp. berkhoffii genotype II from a boy with epithelioid hemangioendothelioma and a dog with hemangiopericytoma. J Clin Microbiol 47(6):1957–1960. doi:10.1128/JCM.00069-09

    PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Maggi RG, Chomel BB, Lappin MR (2010a) Bartonellosis: an emerging infectious disease of zoonotic importance to animals and human beings. J Vet Emerg Crit Care 20(1):8–30. doi:10.1111/j.1476-4431.2009.00496.x

    Google Scholar 

  • Breitschwerdt EB, Maggi RG, Robert Mozayeni B, Hegarty BC, Bradley JM, Mascarelli PE (2010b) PCR amplification of Bartonella koehlerae from human blood and enrichment blood cultures. Parasit Vectors 3:76. doi:10.1186/1756-3305-3-76

    PubMed Central  PubMed  Google Scholar 

  • Breitschwerdt EB, Linder KL, Day MJ, Maggi RG, Chomel BB, Kempf VA (2013) Koch’s postulates and the pathogenesis of comparative infectious disease causation associated with Bartonella species. J Comp Pathol 148(2–3):115–125. doi:10.1016/j.jcpa.2012.12.003

    CAS  PubMed  Google Scholar 

  • Brenner DJ, O’Connor SP, Winkler HH, Steigerwalt AG (1993) Proposals to unify the genera Bartonella and Rochalimaea, with descriptions of Bartonella quintana comb. nov., Bartonella vinsonii comb. nov., Bartonella henselae comb. nov., and Bartonella elizabethae comb. nov., and to remove the family Bartonellaceae from the order Rickettsiales. Int J Syst Bacteriol 43(4):777–786

    CAS  PubMed  Google Scholar 

  • Brenner EC, Chomel BB, Singhasivanon OU, Namekata DY, Kasten RW, Kass PH, Cortes-Vecino JA, Gennari SM, Rajapakse RP, Huong LT, Dubey JP (2013) Bartonella infection in urban and rural dogs from the tropics: Brazil, Colombia, Sri Lanka and Vietnam. Epidemiol Infect 141(1):54–61. doi:10.1017/S0950268812000519

    CAS  PubMed  Google Scholar 

  • Brouqui P, Lascola B, Roux V, Raoult D (1999) Chronic Bartonella quintana bacteremia in homeless patients. N Engl J Med 340(3):184–189. doi:10.1056/NEJM199901213400303

    CAS  PubMed  Google Scholar 

  • Brouqui P, Stein A, Dupont HT, Gallian P, Badiaga S, Rolain JM, Mege JL, La Scola B, Berbis P, Raoult D (2005) Ectoparasitism and vector-borne diseases in 930 homeless people from Marseilles. Medicine (Baltimore) 84(1):61–68

    Google Scholar 

  • Bruce D (1921) Trench fever: final report of the war office trench fever investigation committee. J Hyg 20(3):258–288

    CAS  PubMed Central  PubMed  Google Scholar 

  • Byam W, Lloyd L (1920) Trench fever: its epidemiology and endemiology. Proc R Soc Med 13(Sect Epidemiol State Med):1–27

    CAS  PubMed Central  PubMed  Google Scholar 

  • Cadenas MB, Bradley J, Maggi RG, Takara M, Hegarty BC, Breitschwerdt EB (2008) Molecular characterization of Bartonella vinsonii subsp. berkhoffii genotype III. J Clin Microbiol 46(5):1858–1860. doi:10.1128/jcm.02456-07

    CAS  PubMed Central  PubMed  Google Scholar 

  • Castle KT, Kosoy M, Lerdthusnee K, Phelan L, Bai Y, Gage KL, Leepitakrat W, Monkanna T, Khlaimanee N, Chandranoi K, Jones JW, Coleman RE (2004) Prevalence and diversity of Bartonella in rodents of northern Thailand: a comparison with Bartonella in rodents from southern China. Am J Trop Med Hyg 70(4):429–433

    PubMed  Google Scholar 

  • Chang C, Yamamoto K, Chomel BB, Kasten RW, Simpson DC, Smith CR, Kramer VL (1999) Seroepidemiology of Bartonella vinsonii subsp. berkhoffii infection in California coyotes, 1994–1998. Emerg Infect Dis 5(5):711–715. doi:10.3201/eid0505.990514

    CAS  PubMed Central  PubMed  Google Scholar 

  • Chang CC, Chomel BB, Kasten RW, Heller RM, Ueno H, Yamamoto K, Bleich VC, Pierce BM, Gonzales BJ, Swift PK, Boyce WM, Jang SS, Boulouis HJ, Piemont Y, Rossolini GM, Riccio ML, Cornaglia G, Pagani L, Lagatolla C, Selan L, Fontana R (2000a) Bartonella spp. isolated from wild and domestic ruminants in North America. Emerg Infect Dis 6(3):306–311

    CAS  PubMed Central  PubMed  Google Scholar 

  • Chang CC, Kasten RW, Chomel BB, Simpson DC, Hew CM, Kordick DL, Heller R, Piemont Y, Breitschwerdt EB (2000b) Coyotes (Canis latrans) as the reservoir for a human pathogenic Bartonella sp.: molecular epidemiology of Bartonella vinsonii subsp. berkhoffii infection in coyotes from central coastal California. J Clin Microbiol 38(11):4193–4200

    CAS  PubMed Central  PubMed  Google Scholar 

  • Chang CC, Chomel BB, Kasten RW, Romano V, Tietze N (2001) Molecular evidence of Bartonella spp. in questing adult Ixodes pacificus ticks in California. J Clin Microbiol 39(4):1221–1226. doi:10.1128/JCM.39.4.1221-1226.2001

    CAS  PubMed Central  PubMed  Google Scholar 

  • Chang CC, Hayashidani H, Pusterla N, Kasten RW, Madigan JE, Chomel BB (2002) Investigation of Bartonella infection in ixodid ticks from California. Comp Immunol Microbiol Infect Dis 25(4):229–236

    PubMed  Google Scholar 

  • Cherry NA, Maggi RG, Cannedy AL, Breitschwerdt EB (2009) PCR detection of Bartonella bovis and Bartonella henselae in the blood of beef cattle. Vet Microbiol 135(3–4):308–312. doi:10.1016/j.vetmic.2008.09.063

    CAS  PubMed  Google Scholar 

  • Cherry NA, Maggi RG, Rossmeisl JH, Hegarty BC, Breitschwerdt EB (2011) Ecological diversity of Bartonella species infection among dogs and their owner in Virginia. Vector Borne Zoonotic Dis 11(11):1425–1432. doi:10.1089/vbz.2010.0201

    PubMed  Google Scholar 

  • Cherry NA, Jones SL, Maggi RG, Davis JL, Breitschwerdt EB (2012) Bartonella spp. infection in healthy and sick horses and foals from the southeastern United States. J Vet Intern Med 26(6):1408–1412. doi:10.1111/j.1939-1676.2012.00998.x

    CAS  PubMed  Google Scholar 

  • Childs JE, Olson JG, Wolf A, Cohen N, Fakile Y, Rooney JA, Bacellar F, Regnery RL (1995) Prevalence of antibodies to Rochalimaea species (cat-scratch disease agent) in cats. Vet Rec 136(20):519–520

    CAS  PubMed  Google Scholar 

  • Chitwood MC, Maggi RG, Kennedy-Stoskopf S, Toliver M, Deperno CS (2013) Bartonella vinsonii subsp. berkhoffii in free-ranging white-tailed deer (Odocoileus virginianus). J Wildl Dis 49(2):468–470. doi:10.7589/2012-11-286

    PubMed  Google Scholar 

  • Chomel BB, Kasten RW, Floyd-Hawkins K, Chi B, Yamamoto K, Roberts-Wilson J, Gurfield AN, Abbott RC, Pedersen NC, Koehler JE (1996) Experimental transmission of Bartonella henselae by the cat flea. J Clin Microbiol 34(8):1952–1956

    CAS  PubMed Central  PubMed  Google Scholar 

  • Chomel BB, Boulouis HJ, Breitschwerdt EB (2004) Cat scratch disease and other zoonotic Bartonella infections. J Am Vet Med Assoc 224(8):1270–1279

    PubMed  Google Scholar 

  • Chomel BB, Kasten RW, Henn JB, Molia S (2006) Bartonella infection in domestic cats and wild felids. Ann N Y Acad Sci 1078:410–415. doi:10.1196/annals.1374.080

    PubMed  Google Scholar 

  • Chomel BB, McMillan-Cole AC, Kasten RW, Stuckey MJ, Sato S, Maruyama S, Diniz PP, Breitschwerdt EB (2012) Candidatus Bartonella merieuxii, a potential new zoonotic Bartonella species in canids from Iraq. PLoS Negl Trop Dis 6(9):e1843. doi:10.1371/journal.pntd.0001843

    PubMed Central  PubMed  Google Scholar 

  • Cockerell CJ, Whitlow MA, Webster GF, Friedman-Kien AE (1987) Epithelioid angiomatosis: a distinct vascular disorder in patients with the acquired immunodeficiency syndrome or AIDS-related complex. Lancet 2(8560):654–656

    CAS  PubMed  Google Scholar 

  • Comer JA, Flynn C, Regnery RL, Vlahov D, Childs JE (1996) Antibodies to Bartonella species in inner-city intravenous drug users in Baltimore, MD. Arch Intern Med 156(21):2491–2495

    CAS  PubMed  Google Scholar 

  • Concannon R, Wynn-Owen K, Simpson VR, Birtles RJ (2005) Molecular characterization of haemoparasites infecting bats (Microchiroptera) in Cornwall, UK. Parasitology 131(Pt 4):489–496. doi:10.1017/S0031182005008097

    CAS  PubMed  Google Scholar 

  • Cotte V, Bonnet S, Le Rhun D, Le Naour E, Chauvin A, Boulouis HJ, Lecuelle B, Lilin T, Vayssier-Taussat M (2008) Transmission of Bartonella henselae by Ixodes ricinus. Emerg Infect Dis 14(7):1074–1080. doi:10.3201/eid1407.071110

    CAS  PubMed Central  PubMed  Google Scholar 

  • Daly JS, Worthington MG, Brenner DJ, Moss CW, Hollis DG, Weyant RS, Steigerwalt AG, Weaver RE, Daneshvar MI, O'Connor SP (1993) Rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis. J Clin Microbiol 31(4):872–881

    CAS  PubMed Central  PubMed  Google Scholar 

  • Dehio C, Lanz C, Pohl R, Behrens P, Bermond D, Piemont Y, Pelz K, Sander A (2001) Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer. Int J Syst Evol Microbiol 51(Pt 4):1557–1565

    CAS  PubMed  Google Scholar 

  • Dehio C, Sauder U, Hiestand R (2004) Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a blood-sucking arthropod causing deer ked dermatitis. J Clin Microbiol 42(11):5320–5323. doi:10.1128/JCM.42.11.5320-5323.2004

    PubMed Central  PubMed  Google Scholar 

  • Demers DM, Bass JW, Vincent JM, Person DA, Noyes DK, Staege CM, Samlaska CP, Lockwood NH, Regnery RL, Anderson BE (1995) Cat-scratch disease in Hawaii: etiology and seroepidemiology. J Pediatr 127(1):23–26

    CAS  PubMed  Google Scholar 

  • Diniz PP, Maggi RG, Schwartz DS, Cadenas MB, Bradley JM, Hegarty B, Breitschwerdt EB (2007) Canine bartonellosis: serological and molecular prevalence in Brazil and evidence of co-infection with Bartonella henselae and Bartonella vinsonii subsp. berkhoffii. Vet Res 38(5):697–710. doi:10.1051/vetres:2007023

    CAS  PubMed  Google Scholar 

  • Diniz PP, Billeter SA, Otranto D, De Caprariis D, Petanides T, Mylonakis ME, Koutinas AF, Breitschwerdt EB (2009) Molecular documentation of Bartonella infection in dogs in Greece and Italy. J Clin Microbiol 47(5):1565–1567. doi:10.1128/jcm.00082-09

    CAS  PubMed Central  PubMed  Google Scholar 

  • Drancourt M, Mainardi JL, Brouqui P, Vandenesch F, Carta A, Lehnert F, Etienne J, Goldstein F, Acar J, Raoult D (1995) Bartonella (Rochalimaea) quintana endocarditis in three homeless men. N Engl J Med 332(7):419–423. doi:10.1056/NEJM199502163320702

    CAS  PubMed  Google Scholar 

  • Duncan AW, Maggi RG, Breitschwerdt EB (2007) Bartonella DNA in dog saliva. Emerg Infect Dis 13(12):1948–1950

    PubMed Central  PubMed  Google Scholar 

  • Durden LA, Ellis BA, Banks CW, Crowe JD, Oliver JH Jr (2004) Ectoparasites of gray squirrels in two different habitats and screening of selected ectoparasites for bartonellae. J Parasitol 90(3):485–489. doi:10.1645/GE-3299

    PubMed  Google Scholar 

  • Eldridge BF, Edman J (2003) Medical entomology: a textbook on public health and veterinary problems caused by arthropods, 2nd edn. Springer, New York

    Google Scholar 

  • Ellis BA, Regnery RL, Beati L, Bacellar F, Rood M, Glass GG, Marston E, Ksiazek TG, Jones D, Childs JE (1999) Rats of the genus Rattus are reservoir hosts for pathogenic Bartonella species: an old world origin for a new world disease? J Infect Dis 180(1):220–224. doi:10.1086/314824

    CAS  PubMed  Google Scholar 

  • Eremeeva ME, Gerns HL, Lydy SL, Goo JS, Ryan ET, Mathew SS, Ferraro MJ, Holden JM, Nicholson WL, Dasch GA, Koehler JE (2007) Bacteremia, fever, and splenomegaly caused by a newly recognized Bartonella species. N Engl J Med 356(23):2381–2387

    CAS  PubMed  Google Scholar 

  • Erol E, Jackson C, Bai Y, Sells S, Locke S, Kosoy M (2013) Bartonella bovis isolated from a cow with endocarditis. J Vet Diagn Invest 25(2):288–290. doi:10.1177/1040638713477408

    PubMed  Google Scholar 

  • Eskow E, Rao RV, Mordechai E (2001) Concurrent infection of the central nervous system by Borrelia burgdorferi and Bartonella henselae: evidence for a novel tick-borne disease complex. Arch Neurol 58(9):1357–1363

    CAS  PubMed  Google Scholar 

  • Fenollar F, Sire S, Raoult D (2005) Bartonella vinsonii subsp. arupensis as an agent of blood culture-negative endocarditis in a human. J Clin Microbiol 43(2):945–947

    CAS  PubMed Central  PubMed  Google Scholar 

  • Finkelstein JL, Brown T, O’Reilly KL, Wedincamp J Jr, Foil LD (2002) Studies on the growth of Bartonella henselae in the cat flea (Siphonaptera: Pulicidae). J Med Entomol 39(6):915–919

    PubMed  Google Scholar 

  • Foil L, Andress E, Freeland RL, Roy AF, Rutledge R, Triche PC, O’Reilly KL (1998) Experimental infection of domestic cats with Bartonella henselae by inoculation of Ctenocephalides felis (Siphonaptera: Pulicidae) feces. J Med Entomol 35(5):625–628

    CAS  PubMed  Google Scholar 

  • Fournier PE, Lelievre H, Eykyn SJ, Mainardi JL, Marrie TJ, Bruneel F, Roure C, Nash J, Clave D, James E, Benoit-Lemercier C, Deforges L, Tissot-Dupont H, Raoult D (2001a) Epidemiologic and clinical characteristics of Bartonella quintana and Bartonella henselae endocarditis: a study of 48 patients. Medicine (Baltimore) 80(4):245–251

    CAS  Google Scholar 

  • Fournier PE, Minnick MF, Lepidi H, Salvo E, Raoult D (2001b) Experimental model of human body louse infection using green fluorescent protein-expressing Bartonella quintana. Infect Immun 69(3):1876–1879. doi:10.1128/iai.69.3.1876-1879.2001

    CAS  PubMed Central  PubMed  Google Scholar 

  • Fournier PE, Ndihokubwayo JB, Guidran J, Kelly PJ, Raoult D (2002) Human pathogens in body and head lice. Emerg Infect Dis 8(12):1515–1518. doi:10.3201/eid0812.020111

    PubMed Central  PubMed  Google Scholar 

  • Gabriel MW, Henn J, Foley JE, Brown RN, Kasten RW, Foley P, Chomel BB (2009) Zoonotic Bartonella species in fleas collected on gray foxes (Urocyon cinereoargenteus). Vector Borne Zoonotic Dis 9(6):597–602. doi:10.1089/vbz.2008.0134

    PubMed  Google Scholar 

  • Gil H, Garcia-Esteban C, Barandika JF, Peig J, Toledo A, Escudero R, Jado I, Rodriguez-Vargas M, Garcia-Amil C, Lobo B, Roales P, Rodriguez-Moreno I, Olmeda AS, Garcia-Perez AL, Anda P (2010) Variability of Bartonella genotypes among small mammals in Spain. Appl Environ Microbiol 76(24):8062–8070. doi:10.1128/AEM.01963-10

    CAS  PubMed Central  PubMed  Google Scholar 

  • Giladi M, Maman E, Paran D, Bickels J, Comaneshter D, Avidor B, Varon-Graidy M, Ephros M, Wientroub S (2005) Cat-scratch disease-associated arthropathy. Arthritis Rheum 52(11):3611–3617. doi:10.1002/art.21411

    PubMed  Google Scholar 

  • Gray GC, Johnson AA, Thornton SA, Smith WA, Knobloch J, Kelley PW, Obregon Escudero L, Arones Huayda M, Wignall FS (1990) An epidemic of Oroya fever in the Peruvian Andes. Am J Trop Med Hyg 42(3):215–221

    CAS  PubMed  Google Scholar 

  • Gundi VA, Davoust B, Khamis A, Boni M, Raoult D, La Scola B (2004) Isolation of Bartonella rattimassiliensis sp. nov. and Bartonella phoceensis sp. nov. from European Rattus norvegicus. J Clin Microbiol 42(8):3816–3818. doi:10.1128/JCM.42.8.3816-3818.2004

    PubMed Central  PubMed  Google Scholar 

  • Gundi VA, Taylor C, Raoult D, La Scola B (2009) Bartonella rattaustraliani sp. nov., Bartonella queenslandensis sp. nov. and Bartonella coopersplainsensis sp. nov., identified in Australian rats. Int J Syst Evol Microbiol 59(Pt 12):2956–2961. doi:10.1099/ijs.0.002865-0

    CAS  PubMed  Google Scholar 

  • Gundi VA, Billeter SA, Rood MP, Kosoy MY (2012) Bartonella spp. in rats and zoonoses, Los Angeles, California, USA. Emerg Infect Dis 18(4):631–633. doi:10.3201/eid1804.110816

    PubMed Central  PubMed  Google Scholar 

  • Guptill L (2010) Feline bartonellosis. Vet Clin North Am Small Anim Pract 40(6):1073–1090. doi:10.1016/j.cvsm.2010.07.009

    PubMed  Google Scholar 

  • Guptill L, Slater L, Wu CC, Lin TL, Glickman LT, Welch DF, HogenEsch H (1997) Experimental infection of young specific pathogen-free cats with Bartonella henselae. J Infect Dis 176(1):206–216

    CAS  PubMed  Google Scholar 

  • Guptill L, Wu CC, HogenEsch H, Slater LN, Glickman N, Dunham A, Syme H, Glickman L (2004) Prevalence, risk factors, and genetic diversity of Bartonella henselae infections in pet cats in four regions of the United States. J Clin Microbiol 42(2):652–659

    CAS  PubMed Central  PubMed  Google Scholar 

  • Halos L, Jamal T, Maillard R, Girard B, Guillot J, Chomel B, Vayssier-Taussat M, Boulouis HJ (2004) Role of Hippoboscidae flies as potential vectors of Bartonella spp. infecting wild and domestic ruminants. Appl Environ Microbiol 70(10):6302–6305. doi:10.1128/aem.70.10.6302-6305.2004

    CAS  PubMed Central  PubMed  Google Scholar 

  • Halperin JJ, Wormser GP (2001) Of fleas and ticks on cats and mice. Arch Neurol 58(9):1345–1347

    CAS  PubMed  Google Scholar 

  • Harms CA, Maggi RG, Breitschwerdt EB, Clemons-Chevis CL, Solangi M, Rotstein DS, Fair PA, Hansen LJ, Hohn AA, Lovewell GN, McLellan WA, Pabst DA, Rowles TK, Schwacke LH, Townsend FI, Wells RS (2008) Bartonella species detection in captive, stranded and free-ranging cetaceans. Vet Res 39(6):59. doi:10.1051/vetres:2008036

    PubMed  Google Scholar 

  • Heller R, Riegel P, Hansmann Y, Delacour G, Bermond D, Dehio C, Lamarque F, Monteil H, Chomel B, Piemont Y (1998) Bartonella tribocorum sp. nov., a new Bartonella species isolated from the blood of wild rats. Int J Syst Bacteriol 48(Pt 4):1333–1339

    CAS  PubMed  Google Scholar 

  • Henn JB, Chomel BB, Boulouis HJ, Kasten RW, Murray WJ, Bar-Gal GK, King R, Courreau JF, Baneth G (2009) Bartonella rochalimae in raccoons, coyotes, and red foxes. Emerg Infect Dis 15(12):1984–1987. doi:10.3201/eid1512.081692

    PubMed Central  PubMed  Google Scholar 

  • Hertig M (1942) Phlebotomus and Carrion’s disease. Am J Trop Med Hygiene 22(Suppl.):1–80

    Google Scholar 

  • Higgins JA, Radulovic S, Jaworski DC, Azad AF (1996) Acquisition of the cat scratch disease agent Bartonella henselae by cat fleas (Siphonaptera:Pulicidae). J Med Entomol 33(3):490–495

    CAS  PubMed  Google Scholar 

  • Houpikian P, Raoult D (2005) Blood culture-negative endocarditis in a reference center: etiologic diagnosis of 348 cases. Medicine 84(3):162–173

    PubMed  Google Scholar 

  • Humar A, Salit I (1999) Disseminated Bartonella infection with granulomatous hepatitis in a liver transplant recipient. Liver Transpl Surg 5(3):249–251. doi:10.1002/lt.500050308

    CAS  PubMed  Google Scholar 

  • Ihler GM (1996) Bartonella bacilliformis: dangerous pathogen slowly emerging from deep background. FEMS Microbiol Lett 144(1):1–11

    CAS  PubMed  Google Scholar 

  • Inoue K, Kabeya H, Shiratori H, Ueda K, Kosoy MY, Chomel BB, Boulouis HJ, Maruyama S (2010) Bartonella japonica sp. nov. and Bartonella silvatica sp. nov., isolated from Apodemus mice. Int J Syst Evol Microbiol 60(Pt 4):759–763. doi:10.1099/ijs.0.011528-0

    PubMed  Google Scholar 

  • Jackson LA, Spach DH, Kippen DA, Sugg NK, Regnery RL, Sayers MH, Stamm WE (1996) Seroprevalence to Bartonella quintana among patients at a community clinic in downtown Seattle. J Infect Dis 173(4):1023–1026

    CAS  PubMed  Google Scholar 

  • Jameson P, Greene C, Regnery R, Dryden M, Marks A, Brown J, Cooper J, Glaus B, Greene R (1995) Prevalence of Bartonella henselae antibodies in pet cats throughout regions of North America. J Infect Dis 172(4):1145–1149

    CAS  PubMed  Google Scholar 

  • Jardine C, Appleyard G, Kosoy MY, McColl D, Chirino-Trejo M, Wobeser G, Leighton FA (2005) Rodent-associated Bartonella in Saskatchewan, Canada. Vector Borne Zoonotic Dis 5(4):402–409. doi:10.1089/vbz.2005.5.402

    PubMed  Google Scholar 

  • Jeyaprakash A, Hoy MA, Allsopp MH (2003) Bacterial diversity in worker adults of Apis mellifera capensis and Apis mellifera scutellata (Insecta: Hymenoptera) assessed using 16S rRNA sequences. J Invertebr Pathol 84(2):96–103

    CAS  PubMed  Google Scholar 

  • Johnson R, Ramos-Vara J, Vemulapalli R (2009) Identification of Bartonella henselae in an aborted equine fetus. Vet Pathol 46(2):277–281. doi:10.1354/vp.46-2-277

    CAS  PubMed  Google Scholar 

  • Jones SL, Maggi R, Shuler J, Alward A, Breitschwerdt EB (2008) Detection of Bartonella henselae in the blood of 2 adult horses. J Vet Intern Med 22(2):495–498. doi:10.1111/j.1939-1676.2008.0043.x

    CAS  PubMed  Google Scholar 

  • Kabeya H, Colborn JM, Bai Y, Lerdthusnee K, Richardson JH, Maruyama S, Kosoy MY (2010) Detection of Bartonella tamiae DNA in ectoparasites from rodents in Thailand and their sequence similarity with bacterial cultures from Thai patients. Vector Borne Zoonotic Dis 10(5):429–434. doi:10.1089/vbz.2009.0124

    PubMed  Google Scholar 

  • Kaewmongkol G, Kaewmongkol S, Owen H, Fleming PA, Adams PJ, Ryan U, Irwin PJ, Fenwick SG (2011) Candidatus Bartonella antechini: a novel Bartonella species detected in fleas and ticks from the yellow-footed antechinus (Antechinus flavipes), an Australian marsupial. Vet Microbiol 149(3–4):517–521. doi:10.1016/j.vetmic.2010.12.003

    PubMed  Google Scholar 

  • Kahr A, Kerbl R, Gschwandtner K, Heinzl B, Lackner H, Schwinger W, Stunzner D, Lindbichler F, Urban EC (2000) Visceral manifestation of cat scratch disease in children. A consequence of altered immunological state? Infection 28(2):116–118

    CAS  PubMed  Google Scholar 

  • Karesh WB, Dobson A, Lloyd-Smith JO, Lubroth J, Dixon MA, Bennett M, Aldrich S, Harrington T, Formenty P, Loh EH, Machalaba CC, Thomas MJ, Heymann DL (2012) Ecology of zoonoses: natural and unnatural histories. Lancet 380(9857):1936–1945. doi:10.1016/S0140-6736(12)61678-X

    PubMed  Google Scholar 

  • Kelly PJ, Matthewman LA, Hayter D, Downey S, Wray K, Bryson NR, Raoult D (1996) Bartonella (Rochalimaea) henselae in southern Africa–evidence for infections in domestic cats and implications for veterinarians. J S Afr Vet Assoc 67(4):182–187

    CAS  PubMed  Google Scholar 

  • Kelly PJ, Rooney JJ, Marston EL, Jones DC, Regnery RL (1998) Bartonella henselae isolated from cats in Zimbabwe. Lancet 351(9117):1706

    CAS  PubMed  Google Scholar 

  • Ketring KL, Zuckerman EE, Hardy WD Jr (2004) Bartonella: a new etiological agent of feline ocular disease. J Am Anim Hosp Assoc 40(1):6–12

    PubMed  Google Scholar 

  • Kim CM, Kim JY, Yi YH, Lee MJ, Cho MR, Shah DH, Klein TA, Kim HC, Song JW, Chong ST, O’Guinn ML, Lee JS, Lee IY, Park JH, Chae JS (2005) Detection of Bartonella species from ticks, mites and small mammals in Korea. J Vet Sci 6(4):327–334

    PubMed  Google Scholar 

  • Kim YS, Seo KW, Lee JH, Choi EW, Lee HW, Hwang CY, Shin NS, Youn HJ, Youn HY (2009) Prevalence of Bartonella henselae and Bartonella clarridgeiae in cats and dogs in Korea. J Vet Sci 10(1):85–87

    PubMed Central  PubMed  Google Scholar 

  • Kitchell BE, Fan TM, Kordick D, Breitschwerdt EB, Wollenberg G, Lichtensteiger CA (2000) Peliosis hepatis in a dog infected with Bartonella henselae. J Am Vet Med Assoc 216(4):519–523

    CAS  PubMed  Google Scholar 

  • Koehler JE, Tappero JW (1993) Bacillary angiomatosis and bacillary peliosis in patients infected with human immunodeficiency virus. Clin Infect Dis 17(4):612–624

    CAS  PubMed  Google Scholar 

  • Koehler JE, Quinn FD, Berger TG, LeBoit PE, Tappero JW (1992) Isolation of Rochalimaea species from cutaneous and osseous lesions of bacillary angiomatosis. N Engl J Med 327(23):1625–1631. doi:10.1056/NEJM199212033272303

    CAS  PubMed  Google Scholar 

  • Koehler JE, Glaser CA, Tappero JW (1994) Rochalimaea henselae infection. A new zoonosis with the domestic cat as reservoir. JAMA 271(7):531–535

    CAS  PubMed  Google Scholar 

  • Koehler JE, Sanchez MA, Garrido CS, Whitfeld MJ, Chen FM, Berger TG, Rodriguez-Barradas MC, LeBoit PE, Tappero JW (1997) Molecular epidemiology of bartonella infections in patients with bacillary angiomatosis-peliosis. N Engl J Med 337(26):1876–1883. doi:10.1056/NEJM199712253372603

    CAS  PubMed  Google Scholar 

  • Kordick DL, Breitschwerdt EB (1998) Persistent infection of pets within a household with three Bartonella species. Emerg Infect Dis 4(2):325–328. doi:10.3201/eid0402.980225

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kordick DL, Hilyard EJ, Hadfield TL, Wilson KH, Steigerwalt AG, Brenner DJ, Breitschwerdt EB (1997) Bartonella clarridgeiae, a newly recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease). J Clin Microbiol 35(7):1813–1818

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kordick DL, Brown TT, Shin K, Breitschwerdt EB (1999) Clinical and pathologic evaluation of chronic Bartonella henselae or Bartonella clarridgeiae infection in cats. J Clin Microbiol 37(5):1536–1547

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kosoy MY, Regnery RL, Tzianabos T, Marston EL, Jones DC, Green D, Maupin GO, Olson JG, Childs JE (1997) Distribution, diversity, and host specificity of Bartonella in rodents from the Southeastern United States. Am J Trop Med Hyg 57(5):578–588

    CAS  PubMed  Google Scholar 

  • Kosoy MY, Regnery RL, Kosaya OI, Jones DC, Marston EL, Childs JE (1998) Isolation of Bartonella spp. from embryos and neonates of naturally infected rodents. J Wildl Dis 34(2):305–309

    CAS  PubMed  Google Scholar 

  • Kosoy MY, Saito EK, Green D, Marston EL, Jones DC, Childs JE (2000) Experimental evidence of host specificity of Bartonella infection in rodents. Comp Immunol Microbiol Infect Dis 23(4):221–238

    CAS  PubMed  Google Scholar 

  • Kosoy M, Murray M, Gilmore RD Jr, Bai Y, Gage KL (2003) Bartonella strains from ground squirrels are identical to Bartonella washoensis isolated from a human patient. J Clin Microbiol 41(2):645–650

    CAS  PubMed Central  PubMed  Google Scholar 

  • Kosoy M, Bai Y, Lynch T, Kuzmin IV, Niezgoda M, Franka R, Agwanda B, Breiman RF, Rupprecht CE (2010a) Bartonella spp. in bats, Kenya. Emerg Infect Dis 16(12):1875–1881. doi:10.3201/eid1612.100601

    PubMed Central  PubMed  Google Scholar 

  • Kosoy M, Bai Y, Sheff K, Morway C, Baggett H, Maloney SA, Boonmar S, Bhengsri S, Dowell SF, Sitdhirasdr A, Lerdthusnee K, Richardson J, Peruski LF (2010b) Identification of Bartonella infections in febrile human patients from Thailand and their potential animal reservoirs. Am J Trop Med Hyg 82(6):1140–1145. doi:10.4269/ajtmh.2010.09-0778

    PubMed Central  PubMed  Google Scholar 

  • Kosoy M, Hayman DT, Chan KS (2012) Bartonella bacteria in nature: where does population variability end and a species start? Infect Genet Evol 12(5):894–904. doi:10.1016/j.meegid.2012.03.005

    PubMed  Google Scholar 

  • Kosoy M, Morway C, Sheff KW, Bai Y, Colborn J, Chalcraft L, Dowell SF, Peruski LF, Maloney SA, Baggett H, Sutthirattana S, Sidhirat A, Maruyama S, Kabeya H, Chomel BB, Kasten R, Popov V, Robinson J, Kruglov A, Petersen LR (2008) Bartonella tamiae sp. nov., a newly recognized pathogen isolated from three human patients from Thailand. J Clin Microbiol 46(2):772–775

    PubMed Central  PubMed  Google Scholar 

  • Kostrzewski J (1950) Epidemiology of trench fever. Med Dosw Mikrobiol 2(1):19–51

    CAS  PubMed  Google Scholar 

  • Kruszewska D, Tylewska-Wierzbanowska S (1996) Unknown species of rickettsiae isolated from Ixodes ricinus tick in Walcz. Rocz Akad Med Bialymst 41(1):129–135

    CAS  PubMed  Google Scholar 

  • Lappin MR, Black JC (1999) Bartonella spp infection as a possible cause of uveitis in a cat. J Am Vet Med Assoc 214(8):1205–1207

    CAS  PubMed  Google Scholar 

  • Lappin MR, Hawley J (2009) Presence of Bartonella species and Rickettsia species DNA in the blood, oral cavity, skin and claw beds of cats in the United States. Vet Dermatol 20(5–6):509–514. doi:10.1111/j.1365-3164.2009.00800.x

    PubMed  Google Scholar 

  • Lappin MR, Kordick DL, Breitschwerdt EB (2000) Bartonella spp antibodies and DNA in aqueous humour of cats. J Feline Med Surg 2(1):61–68. doi:10.1053/jfms.2000.0067

    CAS  PubMed  Google Scholar 

  • Leibovitz K, Pearce L, Brewer M, Lappin MR (2008) Bartonella species antibodies and DNA in cerebral spinal fluid of cats with central nervous system disease. J Feline Med Surg 10(4):332–337. doi:10.1016/j.jfms.2007.12.011

    PubMed  Google Scholar 

  • Li DM, Liu QY, Yu DZ, Zhang JZ, Gong ZD, Song XP (2007) Phylogenetic analysis of Bartonella detected in rodent fleas in Yunnan, China. J Wildl Dis 43(4):609–617

    CAS  PubMed  Google Scholar 

  • Lienhardt B, Irani S, Gaspert A, Weishaupt D, Boehler A (2009) Disseminated infection with Bartonella henselae in a lung transplant recipient. J Heart Lung Transplant 28(7):736–739. doi:10.1016/j.healun.2009.03.016

    PubMed  Google Scholar 

  • Lin JW, Chen CY, Chen WC, Chomel BB, Chang CC (2008) Isolation of Bartonella species from rodents in Taiwan including a strain closely related to ‘Bartonella rochalimae’ from Rattus norvegicus. J Med Microbiol 57(Pt 12):1496–1501. doi:10.1099/jmm.0.2008/004671-0

    CAS  PubMed  Google Scholar 

  • Lin JW, Hsu YM, Chomel BB, Lin LK, Pei JC, Wu SH, Chang CC (2012) Identification of novel Bartonella spp. in bats and evidence of Asian gray shrew as a new potential reservoir of Bartonella. Vet Microbiol 156(1–2):119–126. doi:10.1016/j.vetmic.2011.09.031

    PubMed  Google Scholar 

  • Lobanov VA, Gajadhar AA, Al-Adhami B, Schwantje HM (2012) Molecular study of free-ranging mule deer and white-tailed deer from British Columbia, Canada, for evidence of Anaplasma spp. and Ehrlichia spp. Transbound Emerg Dis 59(3):233–243. doi:10.1111/j.1865-1682.2011.01259.x

    CAS  PubMed  Google Scholar 

  • Loftis AD, Gill JS, Schriefer ME, Levin ML, Eremeeva ME, Gilchrist MJ, Dasch GA (2005) Detection of Rickettsia, Borrelia, and Bartonella in Carios kelleyi (Acari: Argasidae). J Med Entomol 42(3):473–480

    CAS  PubMed  Google Scholar 

  • Lucey D, Dolan MJ, Moss CW, Garcia M, Hollis DG, Wegner S, Morgan G, Almeida R, Leong D, Greisen KS et al (1992) Relapsing illness due to Rochalimaea henselae in immunocompetent hosts: implication for therapy and new epidemiological associations. Clin Infect Dis 14(3):683–688

    CAS  PubMed  Google Scholar 

  • MacDonald KA, Chomel BB, Kittleson MD, Kasten RW, Thomas WP, Pesavento P (2004) A prospective study of canine infective endocarditis in northern California (1999–2001): emergence of Bartonella as a prevalent etiologic agent. J Vet Intern Med 18(1):56–64

    PubMed  Google Scholar 

  • Magalhães RF, Pitassi LH, Salvadego M, de Moraes AM, Barjas-Castro ML, Velho PE (2008) Bartonella henselae survives after the storage period of red blood cell units: is it transmissible by transfusion? Transfus Med 18(5):287–291

    PubMed  Google Scholar 

  • Maggi RG, Breitschwerdt EB (2005) Potential limitations of the 16S-23S rRNA intergenic region for molecular detection of Bartonella species. J Clin Microbiol 43(3):1171–1176. doi:10.1128/jcm.43.3.1171-1176.2005

    CAS  PubMed Central  PubMed  Google Scholar 

  • Maggi RG, Duncan AW, Breitschwerdt EB (2005a) Novel chemically modified liquid medium that will support the growth of seven Bartonella species. J Clin Microbiol 43(6):2651–2655. doi:10.1128/jcm.43.6.2651-2655.2005

    CAS  PubMed Central  PubMed  Google Scholar 

  • Maggi RG, Harms CA, Hohn AA, Pabst DA, McLellan WA, Walton WJ, Rotstein DS, Breitschwerdt EB (2005b) Bartonella henselae in porpoise blood. Emerg Infect Dis 11(12):1894–1898

    CAS  PubMed Central  PubMed  Google Scholar 

  • Maggi RG, Chomel B, Hegarty BC, Henn J, Breitschwerdt EB (2006) A Bartonella vinsonii berkhoffii typing scheme based upon 16S-23S ITS and Pap31 sequences from dog, coyote, gray fox, and human isolates. Mol Cell Probes 20(2):128–134. doi:10.1016/j.mcp.2005.11.002

    CAS  PubMed  Google Scholar 

  • Maggi RG, Raverty SA, Lester SJ, Huff DG, Haulena M, Ford SL, Nielsen O, Robinson JH, Breitschwerdt EB (2008) Bartonella henselae in captive and hunter-harvested beluga (Delphinapterus leucas). J Wildl Dis 44(4):871–877

    CAS  PubMed  Google Scholar 

  • Maggi RG, Kosoy M, Mintzer M, Breitschwerdt EB (2009) Isolation of Candidatus Bartonella melophagi from human blood. Emerg Infect Dis 15(1):66–68. doi:10.3201/eid1501.081080

    PubMed Central  PubMed  Google Scholar 

  • Maggi RG, Mascarelli PE, Pultorak EL, Hegarty BC, Bradley JM, Mozayeni BR, Breitschwerdt EB (2011) Bartonella spp. bacteremia in high-risk immunocompetent patients. Diagn Microbiol Infect Dis 71(4):430–437. doi:10.1016/j.diagmicrobio.2011.09.001

    PubMed  Google Scholar 

  • Maman E, Bickels J, Ephros M, Paran D, Comaneshter D, Metzkor-Cotter E, Avidor B, Varon-Graidy M, Wientroub S, Giladi M (2007) Musculoskeletal manifestations of cat scratch disease. Clin Infect Dis 45(12):1535–1540. doi:10.1086/523587

    PubMed  Google Scholar 

  • Marquez FJ, Millan J, Rodriguez-Liebana JJ, Garcia-Egea I, Muniain MA (2009) Detection and identification of Bartonella sp. in fleas from carnivorous mammals in Andalusia, Spain. Med Vet Entomol 23(4):393–398. doi:10.1111/j.1365-2915.2009.00830.x

    CAS  PubMed  Google Scholar 

  • Maruyama S, Nogami S, Inoue I, Namba S, Asanome K, Katsube Y (1996) Isolation of Bartonella henselae from domestic cats in Japan. J Vet Med Sci 58(1):81–83

    CAS  PubMed  Google Scholar 

  • Mascarelli PE, Maggi RG, Hopkins S, Mozayeni BR, Trull CL, Bradley JM, Hegarty BC, Breitschwerdt EB (2013) Bartonella henselae infection in a family experiencing neurological and neurocognitive abnormalities after woodlouse hunter spider bites. Parasit Vectors 6(1):98. doi:10.1186/1756-3305-6-98

    PubMed Central  PubMed  Google Scholar 

  • Matsumoto K, Berrada ZL, Klinger E, Goethert HK, Telford SR 3rd (2008) Molecular detection of Bartonella schoenbuchensis from ectoparasites of deer in Massachusetts. Vector Borne Zoonotic Dis 8(4):549–554. doi:10.1089/vbz.2007.0244

    PubMed Central  PubMed  Google Scholar 

  • McElroy KM, Blagburn BL, Breitschwerdt EB, Mead PS, McQuiston JH (2010) Flea-associated zoonotic diseases of cats in the USA: bartonellosis, flea-borne rickettsioses, and plague. Trends Parasitol 26(4):197–204. doi:10.1016/j.pt.2010.01.001

    PubMed  Google Scholar 

  • McNee JW, Renshaw A (1916) “Trench fever”: a relapsing fever occurring with the British forces in France. Br Med J 1(2876):225–234

    PubMed Central  Google Scholar 

  • Minnick MF, Battisti JM (2009) Pestilence, persistence and pathogenicity: infection strategies of Bartonella. Future Microbiol 4(6):743–758. doi:10.2217/fmb.09.41

    PubMed Central  PubMed  Google Scholar 

  • Morick D, Krasnov BR, Khokhlova IS, Shenbrot GI, Kosoy MY, Harrus S (2010) Bartonella genotypes in fleas (insecta: siphonaptera) collected from rodents in the Negev Desert, Israel. Appl Environ Microbiol 76(20):6864–6869

    CAS  PubMed Central  PubMed  Google Scholar 

  • Nasirudeen AM, Thong ML (1999) Prevalence of Bartonella henselae immunoglobulin G antibodies in Singaporean cats. Pediatr Infect Dis J 18(3):276–278

    CAS  PubMed  Google Scholar 

  • Nelder MP, Reeves WK, Adler PH, Wozniak A, Wills W (2009) Ectoparasites and associated pathogens of free-roaming and captive animals in zoos of South Carolina. Vector Borne Zoonotic Dis 9(5):469–477. doi:10.1089/vbz.2008.0008

    PubMed  Google Scholar 

  • Oskouizadeh K, Zahraei-Salehi T, Aledavood S (2010) Detection of Bartonella henselae in domestic cats’ saliva. Iran J Microbiol 2(2):80–84

    CAS  PubMed Central  PubMed  Google Scholar 

  • Pappalardo BL, Correa MT, York CC, Peat CY, Breitschwerdt EB (1997) Epidemiologic evaluation of the risk factors associated with exposure and seroreactivity to Bartonella vinsonii in dogs. Am J Vet Res 58(5):467–471

    CAS  PubMed  Google Scholar 

  • Pappalardo BL, Brown T, Gookin JL, Morrill CL, Breitschwerdt EB (2000) Granulomatous disease associated with Bartonella infection in 2 dogs. J Vet Intern Med 14(1):37–42

    CAS  PubMed  Google Scholar 

  • Parola P, Shpynov S, Montoya M, Lopez M, Houpikian P, Zeaiter Z, Guerra H, Raoult D (2002) First molecular evidence of new Bartonella spp. in fleas and a tick from Peru. Am J Trop Med Hyg 67(2):135–136

    CAS  PubMed  Google Scholar 

  • Pearce LK, Radecki SV, Brewer M, Lappin MR (2006) Prevalence of Bartonella henselae antibodies in serum of cats with and without clinical signs of central nervous system disease. J Feline Med Surg 8(5):315–320. doi:10.1016/j.jfms.2006.04.001

    PubMed  Google Scholar 

  • Pedersen AB, Altizer S, Poss M, Cunningham AA, Nunn CL (2005) Patterns of host specificity and transmission among parasites of wild primates. Int J Parasitol 35(6):647–657. doi:10.1016/j.ijpara.2005.01.005

    PubMed  Google Scholar 

  • Perez C, Maggi RG, Diniz PP, Breitschwerdt EB (2011) Molecular and serological diagnosis of Bartonella infection in 61 dogs from the United States. J Vet Intern Med 25(4):805–810. doi:10.1111/j.1939-1676.2011.0736.x

    CAS  PubMed  Google Scholar 

  • Perez-Martinez L, Venzal JM, Gonzalez-Acuna D, Portillo A, Blanco JR, Oteo JA (2009) Bartonella rochalimae and other Bartonella spp. in fleas, Chile. Emerg Infect Dis 15(7):1150–1152. doi:10.3201/eid1507.081570

    PubMed Central  PubMed  Google Scholar 

  • Pesavento PA, Chomel BB, Kasten RW, McDonald KA, Mohr FC (2005) Pathology of Bartonella endocarditis in six dogs. Vet Pathol 42(3):370–373. doi:10.1354/vp.42-3-370

    CAS  PubMed  Google Scholar 

  • Pretorius AM, Beati L, Birtles RJ (2004) Diversity of bartonellae associated with small mammals inhabiting Free State province, South Africa. Int J Syst Evol Microbiol 54(Pt 6):1959–1967. doi:10.1099/ijs.0.03033-0

    PubMed  Google Scholar 

  • Pultorak EL, Maggi RG, Mascarelli PE, Breitschwerdt EB (2013) Serial testing from a three-day collection period using the BAPGM platform may enhance the sensitivity of Bartonella spp. detection in bacteremic human patients. J Clin Microbiol. doi:10.1128/JCM.00123-13

    PubMed Central  PubMed  Google Scholar 

  • Raoult D, Roux V (1999) The body louse as a vector of reemerging human diseases. Clin Infect Dis 29(4):888–911. doi:10.1086/520454

    CAS  PubMed  Google Scholar 

  • Raoult D, La Scola B, Kelly PJ, Davoust B, Gomez J (2005) Bartonella bovis in cattle in Africa. Vet Microbiol 105(2):155–156. doi:10.1016/j.vetmic.2004.10.013

    PubMed  Google Scholar 

  • Raoult D, Dutour O, Houhamdi L, Jankauskas R, Fournier PE, Ardagna Y, Drancourt M, Signoli M, La VD, Macia Y, Aboudharam G (2006) Evidence for louse-transmitted diseases in soldiers of Napoleon’s Grand Army in Vilnius. J Infect Dis 193(1):112–120. doi:10.1086/498534

    CAS  PubMed  Google Scholar 

  • Reeves WK, Loftis AD, Gore JA, Dasch GA (2005) Molecular evidence for novel bartonella species in Trichobius major (Diptera: Streblidae) and Cimex adjunctus (Hemiptera: Cimicidae) from two southeastern bat caves, U.S.A. J Vector Ecol 30(2):339–341

    PubMed  Google Scholar 

  • Reeves WK, Nelder MP, Cobb KD, Dasch GA (2006) Bartonella spp. in deer keds, Lipoptena mazamae (Diptera: Hippoboscidae), from Georgia and South Carolina, USA. J Wildl Dis 42(2):391–396

    PubMed  Google Scholar 

  • Reeves WK, Loftis AD, Szumlas DE, Abbassy MM, Helmy IM, Hanafi HA, Dasch GA (2007) Rickettsial pathogens in the tropical rat mite Ornithonyssus bacoti (Acari:Macronyssidae) from Egyptian rats (Rattus spp.). Exp Appl Acarol 41(1–2):101–107

    CAS  PubMed  Google Scholar 

  • Regnery RL, Anderson BE, Clarridge JE 3rd, Rodriguez-Barradas MC, Jones DC, Carr JH (1992) Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from blood of a febrile, human immunodeficiency virus-positive patient. J Clin Microbiol 30(2):265–274

    CAS  PubMed Central  PubMed  Google Scholar 

  • Regnery RL, Childs JE, Koehler JE (1995) Infections associated with Bartonella species in persons infected with human immunodeficiency virus. Clin Infect Dis 21(Suppl 1):S94–S98

    PubMed  Google Scholar 

  • Reis C, Cote M, Le Rhun D, Lecuelle B, Levin ML, Vayssier-Taussat M, Bonnet SI (2011) Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. PLoS Negl Trop Dis 5(5):e1186. doi:10.1371/journal.pntd.0001186

    PubMed Central  PubMed  Google Scholar 

  • Relman DA (1995) Has trench fever returned? N Engl J Med 332(7):463–464. doi:10.1056/NEJM199502163320710

    CAS  PubMed  Google Scholar 

  • Rolain JM, Rousset E, La Scola B, Duquesnel R, Raoult D (2003) Bartonella schoenbuchensis isolated from the blood of a French cow. Ann N Y Acad Sci 990:236–238

    CAS  PubMed  Google Scholar 

  • Rolain JM, Bourry O, Davoust B, Raoult D (2005) Bartonella quintana and Rickettsia felis in Gabon. Emerg Infect Dis 11(11):1742–1744. doi:10.3201/eid1111.050861

    PubMed Central  PubMed  Google Scholar 

  • Rotstein DS, Taylor SK, Bradley J, Rieitschwerdt EB (2000) Prevalence of Bartonella henselae antibody in Florida panthers. J Wildl Dis 36(1):157–160

    CAS  PubMed  Google Scholar 

  • Roux V, Eykyn SJ, Wyllie S, Raoult D (2000) Bartonella vinsonii subsp. berkhoffii as an agent of afebrile blood culture-negative endocarditis in a human. J Clin Microbiol 38(4):1698–1700

    CAS  PubMed Central  PubMed  Google Scholar 

  • Sasaki T, Kobayashi M, Agui N (2002) Detection of Bartonella quintana from body lice (Anoplura: Pediculidae) infesting homeless people in Tokyo by molecular technique. J Med Entomol 39(3):427–429

    PubMed  Google Scholar 

  • Sasaki T, Poudel SK, Isawa H, Hayashi T, Seki N, Tomita T, Sawabe K, Kobayashi M (2006) First molecular evidence of Bartonella quintana in Pediculus humanus capitis (Phthiraptera: Pediculidae), collected from Nepalese children. J Med Entomol 43(1):110–112

    CAS  PubMed  Google Scholar 

  • Schaefer JD, Kasten RW, Coonan TJ, Clifford DL, Chomel BB (2011) Isolation or detection of Bartonella vinsonii subspecies berkhoffii and Bartonella rochalimae in the endangered island foxes (Urocyon littoralis). Vet Microbiol 154(1–2):135–139. doi:10.1016/j.vetmic.2011.06.031

    PubMed  Google Scholar 

  • Schaefer JD, Moore GM, Namekata MS, Kasten RW, Chomel BB (2012) Seroepidemiology of Bartonella infection in gray foxes from Texas. Vector Borne Zoonotic Dis 12(5):428–430. doi:10.1089/vbz.2011.0805

    PubMed Central  PubMed  Google Scholar 

  • Schultz MG (1968) A history of bartonellosis (Carrion’s disease). Am J Trop Med Hyg 17(4):503–515

    CAS  PubMed  Google Scholar 

  • Serratrice J, Rolain JM, Granel B, Ene N, Conrath J, Avierinos JF, Disdier P, Raoult D, Weiller PJ (2003) Bilateral retinal artery branch occlusions revealing Bartonella grahamii infection. Rev Med Interne 24(9):629–630

    CAS  PubMed  Google Scholar 

  • Slater LN, Welch DF, Hensel D, Coody DW (1990) A newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia. N Engl J Med 323(23):1587–1593. doi:10.1056/NEJM199012063232303

    CAS  PubMed  Google Scholar 

  • Smarick SD, Jandery KE, Chomel BB, Thomas WP, Aldrich J (2004) Aortic valvular endocarditis caused by Bartonella vinsonii subsp. berkhoffii in 2 dogs presenting for fulminant pulmonary edema. J Vet Emerg Crit Care 14:42–51

    Google Scholar 

  • Spach DH, Callis KP, Paauw DS, Houze YB, Schoenknecht FD, Welch DF, Rosen H, Brenner DJ (1993) Endocarditis caused by Rochalimaea quintana in a patient infected with human immunodeficiency virus. J Clin Microbiol 31(3):692–694

    CAS  PubMed Central  PubMed  Google Scholar 

  • Spach DH, Kanter AS, Daniels NA, Nowowiejski DJ, Larson AM, Schmidt RA, Swaminathan B, Brenner DJ (1995a) Bartonella (Rochalimaea) species as a cause of apparent “culture-negative” endocarditis. Clin Infect Dis 20(4):1044–1047

    CAS  PubMed  Google Scholar 

  • Spach DH, Kanter AS, Dougherty MJ, Larson AM, Coyle MB, Brenner DJ, Swaminathan B, Matar GM, Welch DF, Root RK et al (1995b) Bartonella (Rochalimaea) quintana bacteremia in inner-city patients with chronic alcoholism. N Engl J Med 332(7):424–428. doi:10.1056/nejm199502163320703

    CAS  PubMed  Google Scholar 

  • Sreter-Lancz Z, Tornyai K, Szell Z, Sreter T, Marialigeti K (2006) Bartonella infections in fleas (Siphonaptera: Pulicidae) and lack of bartonellae in ticks (Acari: Ixodidae) from Hungary. Folia Parasitol 53(4):313–316

    PubMed  Google Scholar 

  • Strong RP, Tyzzer E, Brues CT, Sellards AW, Gastiaburu JC (1915) Report of the first expedition to South America. Havard University Press, Cambridge

    Google Scholar 

  • Suksawat J, Pitulle C, Arraga-Alvarado C, Madrigal K, Hancock SI, Breitschwerdt EB (2001) Coinfection with three Ehrlichia species in dogs from Thailand and Venezuela with emphasis on consideration of 16S ribosomal DNA secondary structure. J Clin Microbiol 39(1):90–93. doi:10.1128/JCM.39.1.90-93.2001

    CAS  PubMed Central  PubMed  Google Scholar 

  • Sun J, Fu G, Lin J, Song X, Lu L, Liu Q (2010) Seroprevalence of Bartonella in Eastern China and analysis of risk factors. BMC Infect Dis 10:121. doi:10.1186/1471-2334-10-121

    PubMed Central  PubMed  Google Scholar 

  • Swift HF (1920) Trench fever. Arch Intern Med 26(1):76–98

    Google Scholar 

  • Sykes JE, Henn JB, Kasten RW, Allen C, Chomel BB (2007) Bartonella henselae infection in splenectomized domestic cats previously infected with hemotropic Mycoplasma species. Vet Immunol Immunopathol 116(1–2):104–108. doi:10.1016/j.vetimm.2006.12.004

    PubMed  Google Scholar 

  • Telfer S, Begon M, Bennett M, Bown KJ, Burthe S, Lambin X, Telford G, Birtles R (2007a) Contrasting dynamics of Bartonella spp. in cyclic field vole populations: the impact of vector and host dynamics. Parasitology 134(Pt 3):413–425. doi:10.1017/S0031182006001624

    CAS  PubMed Central  PubMed  Google Scholar 

  • Telfer S, Clough HE, Birtles LR, Bennett M, Carslake D, Helyar S, Begon M (2007b) Ecological differences and coexistence in a guild of microparasites: Bartonella in wild rodents. Ecology 88(7):1841–1849

    PubMed  Google Scholar 

  • Thudi KR, Kreikemeier JT, Phillips NJ, Salvalaggio PR, Kennedy DJ, Hayashi PH (2007) Cat scratch disease causing hepatic masses after liver transplant. Liver Int 27(1):145–148. doi:10.1111/j.1478-3231.2006.01386.x

    PubMed  Google Scholar 

  • Townsend CH (1914) On the identity of Verruga and Carrion’s fever. Science 39(994):99–100. doi:10.1126/science.39.994.99

    CAS  PubMed  Google Scholar 

  • Tsukahara M, Tsuneoka H, Iino H, Ohno K, Murano I (1998) Bartonella henselae infection from a dog. Lancet 352(9141):1682

    CAS  PubMed  Google Scholar 

  • Tsai YL, Chuang ST, Chang CC, Kass PH, Chomel BB (2010) Bartonella species in small mammals and their ectoparasites in Taiwan. Am J Trop Med Hyg 83(4):917–923

    PubMed Central  PubMed  Google Scholar 

  • Turnbull BS, Cowan DF (1999) Angiomatosis, a newly recognized disease in Atlantic bottlenose dolphins (Tursiops truncatus) from the Gulf of Mexico. Vet Pathol 36(1):28–34

    CAS  PubMed  Google Scholar 

  • Tuttle AD, Birkenheuer AJ, Juopperi T, Levy MG, Breitschwerdt EB (2003) Concurrent bartonellosis and babesiosis in a dog with persistent thrombocytopenia. J Am Vet Med Assoc 223(9):1306–1310, 1280–1301

    PubMed  Google Scholar 

  • Valerio CR, Murray P, Arlian LG, Slater JE (2005) Bacterial 16S ribosomal DNA in house dust mite cultures. J Allergy Clin Immunol 116(6):1296–1300. doi:10.1016/j.jaci.2005.09.046

    CAS  PubMed  Google Scholar 

  • Varanat M, Maggi RG, Linder KE, Breitschwerdt EB (2011) Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma sp. in dogs with splenic disease. J Vet Intern Med 25(6):1284–1291. doi:10.1111/j.1939-1676.2011.00811.x

    CAS  PubMed  Google Scholar 

  • Varanat M, Broadhurst J, Linder KE, Maggi RG, Breitschwerdt EB (2012) Identification of Bartonella henselae in 2 cats with pyogranulomatous myocarditis and diaphragmatic myositis. Vet Pathol 49(4):608–611. doi:10.1177/0300985811404709

    CAS  PubMed  Google Scholar 

  • Varela G, Fournier R, Mooser H (1954) Presence of Rickettsia quintana in Pediculus humanus from Mexico City; experimental inoculation. Rev Inst Salubr Enferm Trop 14(1):39–42

    CAS  PubMed  Google Scholar 

  • Vinson JW, Varela G, Molina-Pasquel C (1969) Trench fever. 3. Induction of clinical disease in volunteers inoculated with Rickettsia quintana propagated on blood agar. Am J Trop Med Hyg 18(5):713–722

    CAS  PubMed  Google Scholar 

  • Welch DF, Pickett DA, Slater LN, Steigerwalt AG, Brenner DJ (1992) Rochalimaea henselae sp. nov., a cause of septicemia, bacillary angiomatosis, and parenchymal bacillary peliosis. J Clin Microbiol 30(2):275–280

    CAS  PubMed Central  PubMed  Google Scholar 

  • Welch DF, Carroll KC, Hofmeister EK, Persing DH, Robison DA, Steigerwalt AG, Brenner DJ (1999) Isolation of a new subspecies, Bartonella vinsonii subsp. arupensis, from a cattle rancher: identity with isolates found in conjunction with Borrelia burgdorferi and Babesia microti among naturally infected mice. J Clin Microbiol 37(8):2598–2601

    CAS  PubMed Central  PubMed  Google Scholar 

  • Whittemore JC, Hawley JR, Radecki SV, Steinberg JD, Lappin MR (2012) Bartonella species antibodies and hyperglobulinemia in privately owned cats. J Vet Intern Med 26(3):639–644. doi:10.1111/j.1939-1676.2012.00925.x

    CAS  PubMed  Google Scholar 

  • Winoto IL, Goethert H, Ibrahim IN, Yuniherlina I, Stoops C, Susanti I, Kania W, Maguire JD, Bangs MJ, Telford SR 3rd, Wongsrichanalai C (2005) Bartonella species in rodents and shrews in the greater Jakarta area. Southeast Asian J Trop Med Public Health 36(6):1523–1529

    PubMed  Google Scholar 

  • Woolhouse ME, Taylor LH, Haydon DT (2001) Population biology of multihost pathogens. Science 292(5519):1109–1112

    CAS  PubMed  Google Scholar 

  • Yager JA, Best SJ, Maggi RG, Varanat M, Znajda N, Breitschwerdt EB (2010) Bacillary angiomatosis in an immunosuppressed dog. Vet Dermatol 21(4):420–428. doi:10.1111/j.1365-3164.2010.00879.x

    PubMed  Google Scholar 

  • Ying B, Kosoy MY, Maupin GO, Tsuchiya KR, Gage KL (2002) Genetic and ecologic characteristics of Bartonella communities in rodents in southern China. Am J Trop Med Hyg 66(5):622–627

    CAS  PubMed  Google Scholar 

  • Zangwill KM, Hamilton DH, Perkins BA, Regnery RL, Plikaytis BD, Hadler JL, Cartter ML, Wenger JD (1993) Cat scratch disease in Connecticut. Epidemiology, risk factors, and evaluation of a new diagnostic test. N Engl J Med 329(1):8–13

    CAS  PubMed  Google Scholar 

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  1. Department of Clinical Sciences, Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, 27607, USA

    Elizabeth L. Pultorak, Ricardo G. Maggi & Edward B. Breitschwerdt

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  1. Elizabeth L. Pultorak
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  2. Ricardo G. Maggi
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  1. Department of Veterinary Medical Science, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan

    Akio Yamada

  2. Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, New Jersey, USA

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    Bruce Kaplan

  4. Hookipa BioTech AG, Townsend, Massachusetts, USA

    Thomas P. Monath

  5. (emeritus), Rio de Janeiro, Brazil

    Jack Woodall

  6. Florida Department of Agriculture and Consumer Services, Tallahassee, Florida, USA

    Lisa Conti

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Pultorak, E.L., Maggi, R.G., Breitschwerdt, E.B. (2014). Bartonellosis: A One Health Perspective. In: Yamada, A., Kahn, L., Kaplan, B., Monath, T., Woodall, J., Conti, L. (eds) Confronting Emerging Zoonoses. Springer, Tokyo. https://doi.org/10.1007/978-4-431-55120-1_6

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