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UDP-GlcNAc: BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 4 (B3GNT4)

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Handbook of Glycosyltransferases and Related Genes

Abstract

β1,3-N-Acetylglucosaminyltransferase (β3GnT) enzymes synthesize a unique carbohydrate structure known as polylactosamine (poly-N-acetyllactosamine). Polylactosamines are carried on N- and O-glycans and glycolipids. Polylactosamine units are considered as integral components serving as a fundamental structure and backbone for carbohydrate assemblies (Fig. 28.1).

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References

  • Shiraishi N, Natsume A, Togayachi A, Endo T, Akashima T, Yamada Y, Imai N, Nakagawa S, Koizumi S, Sekine S, Narimatsu H, Sasaki K (2001) Identification and characterization of three novel β1,3-N-acetylglucosaminyltransferases structurally related to the β1,3-galactosyltransferase family. J Biol Chem 276:3498–3507

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Correspondence to Akira Togayachi .

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© 2014 Springer Japan

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Togayachi, A., Narimatsu, H. (2014). UDP-GlcNAc: BetaGal Beta-1,3-N-Acetylglucosaminyltransferase 4 (B3GNT4). In: Taniguchi, N., Honke, K., Fukuda, M., Narimatsu, H., Yamaguchi, Y., Angata, T. (eds) Handbook of Glycosyltransferases and Related Genes. Springer, Tokyo. https://doi.org/10.1007/978-4-431-54240-7_90

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