Abstract
Cerebral vasospasm after subarachnoid hemorrhage (SAH) is a combination of prolonged contraction and vessel remodeling that may lead to cerebral ischemia or infarction [2]. Morphological studies of cerebral arteries affected by vasospasm often show extensive necrosis of smooth-muscle cells [1] as well as desquamation and dystrophy of endothelial cells [7, 11]. The actual mechanisms of cellular death following cerebral vasospasm are not known. Recent studies of post-SAH vasospasm in this laboratory strongly suggest that endothelial cells may be dying through apoptotic pathways [8, 10].
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© 2001 Springer-Verlag
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Zubkov, A.Y., Tibbs, R.E., Clower, B., Ogihara, K., Aoki, K., Zhang, J.H. (2001). Apoptosis in Basilar Endothelial Cells in a Canine Double Hemorrhage Model. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_7
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DOI: https://doi.org/10.1007/978-3-7091-6232-3_7
Publisher Name: Springer, Vienna
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