Abstract
Tirilazad mesylate is the first of the new generation of 21-aminosteroid drugs [1] to come into clinical use. The steroid molecule was modified to remove the usual steroid side effects, and by the addition of a large amine molecule to the 21 carbon. It is a potent inhibitor of iron-dependent lipid peroxidation and free radical scavenger.
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© 2001 Springer-Verlag
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Dorsch, N.W.C., Kassell, N.F., Sinkula, M.S. (2001). Metaanalysis of Trials of Tirilazad Mesylate in Aneurysmal SAH. In: Seiler, R.W., Steiger, HJ. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplements, vol 77. Springer, Vienna. https://doi.org/10.1007/978-3-7091-6232-3_50
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DOI: https://doi.org/10.1007/978-3-7091-6232-3_50
Publisher Name: Springer, Vienna
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