Zusammenfassung
Die arterielle Perfusion des Gastrointestinaltraktes erfolgt durch den Truncus coeliacus sowie die Arteria mesenterica superior und inferior. Der Truncus coeliacus (TC) versorgt neben Magen und Duodenum die Milz und das hepatobiliäre System. Die Arteria mesenterica superior (AMS) speist das Jejunum, Ileum sowie Colon ascendens und transversum. Die Arteria mesenterica inferior versorgt den Bereich vom Colon transversum bis zum Rektum. Robuste Kollateralen zwischen den 3 Hauptgefäßen (Arteria pancreaticoduodenalis superior und inferior, Riolan-Arkade), können dazu führen, dass langsam sich entwickelnde Stenosen oder Verschlüsse eines oder zwei der Hauptarterien asymptomatisch bleiben (Abb. 1). Die plötzliche Okklusion eines der 3 mesenterialen Hauptäste ohne vorherige Ausbildung eines kollateralen Netzwerkes verursacht hingegen schwere Darmischämien. Die akute mesenteriale Ischämie (AMI) ist ein chirurgischer Notfall mit einer gut dokumentierten hohen Mortalitätsrate innerhalb des Krankenhauses zwischen 59 % und 94 % (Kassahun et al. 2008). Pathophysiologisch liegen der AMI eine arterielle Embolie, eine arterielle Thrombose, eine nicht-okkludierende mesenteriale Ischämie (NOMI) oder eine mesenteriale Venenthrombose zugrunde. Der Fokus dieses Kapitels liegt auf der Behandlung der AMI.
Der Herausgeber Eike Sebastian Debus hat diesen Beitrag übersetzt und freigegeben
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Literatur
Acosta S, Nilsson T (2012) Current status on plasma biomarkers for acute mesenteric ischemia. J Thromb Thrombolysis 33(4):355–361
Acosta S, Sonesson B, Resch T (2009) Endovascular therapeutic approaches for acute superior mesenteric artery occlusion. Cardiovac Intervent Radiol 32(5):896–905
Al-thani H, El-Mabrok J, El-Menyar A, Al-Sulaiti M, Tabeb AH, Hajaji K, Elgohary H, Asim M, Latifi R (2014) Clinical presentation and outcome of mesenteric vein thrombosis: a single center experience. Angiology 66(3):249–256
Arthurs ZM (2011) A comparison of endovascular revascularization with traditional therapy for the treatment of acute mesenteric ischemia. J Vasc Surg 53(3):698–705
Bailey RW (1987) Protection of the small intestine from non-occlusive mesenteric ischemai injury due to cardiogenic shock. Am J Surg 153(1):108–116
Ballard J (1993) A critical analysis of adjuvant techniques used to assess bowel viability in acute mesenteric ischemia. Am Surg 59(5):309–311
Bradbury AW (1995) Mesenteric ischemia: a multidisciplinary approach. Br J Surg 82(11):1446–1459
Brunaud L (2001) Acute mesenteric venous thrombosis: case of nonoperative management. J Vasc Surg 34(4):673–679
Coelho Macedo RA, Oderich GS, Kalra M, Stone D, Woo E, Panneton J et al (2014) Multicenter experience with retrograde open mesenteric artery stenting via laparotomy for treatment of acute and chronic mesenteric ischemia. J Vasc Surg 59(2):565–566
Cronenwett JL, Johnston KW (Hrsg) (2010) Rutherfordʼs vascular surgery, 2010. Aufl. Mosby, New York.
Edwards MS, Cherr GS, Craven TE, Olsen AW, Plonk GW, Geary RL, Ligush JL, Hansen KJ (2003) Acute occlusive mesenteric ischemia: surgical management and outcomes. Ann Vasc Surg 17(1):72–79
Endean ED, Barnes SL, Kwolek CJ, Minion DJ, Schwarcz TH, Mentzer RM Jr (2001) Surgical management of thrombotic acute intestinal ischemia. Ann Surg 233(6):801–808
Furrer J, Grüntzig A, Kugelmeier J et al (1980) Treatment of abdominal angina with percutaneous dilatation of an arteria mesenteric superior stenosis: preliminary communication. Cardiovac Intervent Radiol 3:43–44
Furukawa A (2009) CT diagnosis of acute mesenteric ischemia from various causes. Am J Roentgenol 192(2):408–416
Gollin GM, Marks C, Marks WH (1993) Intestinal fatty acid binding protein in serum and urine reflects early ischemic injury to the small bowel. Surgery 113(5):545–551
Hechtman JF, Lento PA, Scordi-bello I (2011) Ischemic bowel due to embolization from an isolated mobile thrombus of the ascending aorta: a case report and review of the literature. J Thromb Thrombolysis 32(2):238–241
Heiss P, Loewenhardt B, Manke C, Hellinger A, Dietl KH, Schitt HJ, Scheibl K, Feuerbach S, Paetzel C (2010) Primary percutaneous aspiration and thrombolysis for the treatment of acute embolic superior mesenteric artery occlusion. Eur Radiol 20(12):2948–2958
Jarvinen O, Laurikka J, Sisto T, Tarkka MR (1996) Intestinal ischemia following surgery for aorto-iliac disease. A review of 502 consecutive aortic reconstructions. Vasa 25(2):148–155
Kanda T (1996) Intestinal fatty acid-binding protein is a useful diagnostic marker for mesenteric infarction in humans. Gastroenterology 110(2):339–343
Kassahun WT, Schulz T, Richter O, Hauss J (2008) Unchanged high mortality rates from acute occlusive intestinal ischemia: six year review. Langenbeck’s Arch Surg 393(2):163–171
Klass A (1951) Embolectomy in acute mesenteric occlusion. Ann Surg 134:913–917
Klempnauer J (1997) Long-term results after surgery for acute mesenteric ischemia. Surgery 121(3):239–243
Kougias P et al (2007) Determinants of mortality and treatment outcome following surgical interventions for acute mesenteric ischemia. J Vasc Surg 46(3):467–474
Kurt Y (2005) D-dimer in the early diagnosis of acute mesenteric ischemia secondary to arterial occlusion in rats. Eur Surg Res 37(4):216–219
Lock G (2001) Acute intestinal ischaemia. Best Pract Res Clin Gastroenterol 15:83–98
Mamode N, Pickford I, Leiberman P (1999) Failure to improve outcome in acute mesenteric ischemia: seven year review. Eur J Surg 165(3):203–208
Mansour M (1999) Management of acute mesenteric ischemia. Arch Surg 134(3):328–330
Oderich GS (2009) Open versus endovascular revascularization for chronic mesenteric ischemia: risk-stratified outcomes. J Vasc Surg 49(6):1472–1479
Ofer A (2009) Multidetector CT angiography in the evaluation of acute mesenteric ischemia. Eur Radiol 19(1):24–30
Oldenburg WA (2004) Acute mesenteric ischemia: a clinical review. Arch Intern Med 164(10):1054–1062
Park WM, Gloviczki P, Cherry KJ Jr, Hallett JW Jr, Bower TC, Panneton JM et al (2002) Contemporary management of acute mesenteric ischemia: factors associated with survival. J Vasc Surg 35(3):445–452
Pfeifer M, Kogel H, Heymer B (1990) Cholesterol crystal embolization, a rare cause of postoperative ischemic colitis. Vasa 19(1):54–58
Plessier A (2010) Acute portal vein thrombosis unrelated to cirrhosis: a prospective multicenter follow-up study. Hepatology 51(1):210–218
Rastan AJ, Tillmann E, Subramanian S, Lehmkuhl L, Funkat AK, Leontyev S et al (2010) Visceral arterial compromise during intra-aortic balloon counterpulsation therapy. Circulation 122(11):S92–S99
Rhee RY (1994) Mesenteric venous thrombosis: still a lethal disease in the 1990s. J Vasc Surg 20(5):688–697
Ryer EJ (2012) Revascularization for acute mesenteric ischemia. J Vasc Surg 55(6):1682–1689
Ryer EJ, Kalra M, Oderich GS, Duncan AA, Gloviczki P, Cha S et al (2012) Revascularization for acute mesenteric ischemia. J Vasc Surg 55(6):1682–1689
Saric M, Kronzon I (2012) Aortic atherosclerosis and embolic events. Curr Cardiol Rep 14(3):342–349
Schaefer PJ (2013) Comparison of non-invasive imaging modalities for stenosis grading in mesenteric arteries. Rofo 185(7):628–634
Schermerhorn ML (2009) Mesenteric revascularization: management and outcomes in the United States. J Vasc Surg 50(2):341–348
Singal AK, Kamath PS, Tefferi A (2013) Mesenteric venous thrombosis. Mayo Clin Proc 88(3):285–294
Sonesson B (2008) Hybrid recanalization of superior mesenteric artery occlusion in acute mesenteric ischemia. J Endovasc Ther 15(1):129–132
Stamatakos M, Stefanaki C, Mastrokalos D, Arampatzi H, Safioleas P, Chatziconstantinou C, Xiromeritis C, Safioleas M (2008) Mesenteric ischemia: still a deadly puzzle for the medical community. Tohoku J Exp Med 216(3):197–204
Stefanutti U (1968) Antonio Benivieni, Florentine surgeon and father of pathological anatomy. Osp Ital Chir 18(3):306–311
Stoney RC, Cunningham CG (1993) Acute mesenteric ischemia. Surgery 114(3):489–490
Thuijls G (2011) Early diagnosis of intestinal inschemia using urinary and plasma fatty acid binding proteins. Ann Surg 253(2):303–308
Trompeter M (2002) Non-occlusive mesenteric ischemia: etiology, diagnosis, and interventional therapy. Eur Radiol 12(5):1179–1187
Wasilewska M, Gosk-Bierska I (2013) Thromboembolism associated with atrial fibrillation as a cause of limb and organ ischemia. Adv Clin Exp Med 22(6):865–873
Wilson DB (2006) Clinical course of mesenteric artery stenosis in elderly americans. Arch Intern Med 166(19):2095–2100
Wyers MC (2007) Retrograde mesenteric stenting during laparotomy for acute occlusive mesenteric ischemia. J Vasc Surg 45(2):269–275
Zhang WW, Kulaylat MN, Anain PM, Dosluoglu HH, Harris LM, Cherr GS et al (2004) Embolization as cause of bowel ischemia after endovascular abdominal aortic aneurysm repair. J Vasc Surg 40(5):867–872
Zwolak RF, Fillinger MF, Walsh DB et al (1998) Mesenteric and celiac duplex scanning: a validation study. J Vasc Surg 27:1078–1087
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Erben, Y., Oderich, G.S., Debus, E.S. (2020). Akute mesenteriale Ischämie. In: Debus, E., Gross-Fengels, W. (eds) Operative und interventionelle Gefäßmedizin. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53380-2_78
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