Skip to main content
SpringerLink
Log in

Pharmakotherapie im Alter

  • Chapter
  • First Online:
Book cover Lebensqualität im Alter

  • 5642 Accesses

Zusammenfassung

Das Thema Pharmakotherapie im Alter spannt sich von der Unterbehandlung potenziell heilbarer Erkrankungen, der richtigen Indikationsstellung zur Behandlung bei oftmals multimorbiden Älteren mit kurzer verbleibender Lebenszeit, über die Priorisierung der Diagnosen unter Berücksichtigung der Funktionalität und bestehenden Organeinschränkungen bis zur exakten individuell optimierten Differenzialtherapie unter Beachtung von Interaktionen und Begleiterkrankungen. Eine wesentliche Aufgabe des behandelnden Arztes ist es, die persönlichen Wünsche und das soziale Umfeld zu erfassen, um die Adhärenz zur Verschreibungen hochzuhalten.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 74.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Bergert FW, Braun M, Ehrenthal K, Feßler J, Gross J, Hüttner U, Kluthe B, Liesenfeld A, Seffrin J, Vetter G, Beyer M, Muth C, Popert U, Harder S, Kirchner H, Schubert I (2014) Recommendations for treating adult and geriatric patients on multimedication. Int J Clin Pharmacol Ther 52, Suppl 1: 1–64

    Article  PubMed  Google Scholar 

  • Bradley MC, Motterlini N, Padmanabhan S, Cahir C, Williams T, Fahey T, Hughes CM (2014) Potentially inappropriate prescribing among older people in the United Kingdom. BMC Geriatr 14: 72

    Article  PubMed  PubMed Central  Google Scholar 

  • Brahma DK, Wahlang JB, Marak MD, Sangma M (2013) Adverse drug reactions in the elderly. J Pharmacol Pharmacother 4: 91–94

    Article  PubMed  PubMed Central  Google Scholar 

  • Buess D, Kressig RW (2013) Sarcopenia: definition, diagnostics and therapy. Praxis (Bern 1994) 102: 1167–1170

    Article  Google Scholar 

  • Chen Y, Zhu LL, Zhou Q (2014) Effects of drug pharmacokinetic/pharmacodynamic properties, characteristics of medication use, and relevant pharmacological interventions on fall risk in elderly patients. Ther Clin Risk Manag 10: 437–448

    CAS  PubMed  PubMed Central  Google Scholar 

  • Cherubini A, Corsonello A, Lattanzio F (2012) Underprescription of beneficial medicines in older people: causes, consequences and prevention. Drugs Aging 29: 463–475

    Article  CAS  PubMed  Google Scholar 

  • Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M, European Working Group on Sarcopenia in Older P (2010) Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing 39: 412–423

    Article  PubMed  PubMed Central  Google Scholar 

  • Di Francesco V, Fantin F, Omizzolo F, Residori L, Bissoli L, Bosello O, Zamboni M (2007) The anorexia of aging. Dig Dis 25: 129–137

    Article  PubMed  Google Scholar 

  • Dovjak P (2012) Tools in polypharmacy. Current evidence from observational and controlled studies. Z Gerontol Geriatr 45: 468–472

    Article  CAS  PubMed  Google Scholar 

  • Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, Seeman T, Tracy R, Kop WJ, Burke G, McBurnie MA, Group CHSCR (2001) Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 56: M146–156

    Article  CAS  PubMed  Google Scholar 

  • Gallagher P, O'Mahony D (2008) STOPP (Screening Tool of Older Personsʼ potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beersʼ criteria. Age Ageing 37: 673–679

    Article  PubMed  Google Scholar 

  • Gandhi TK, Weingart SN, Borus J, Seger AC, Peterson J, Burdick E, Seger DL, Shu K, Federico F, Leape LL, Bates DW (2003) Adverse drug events in ambulatory care. N Engl J Med 348: 1556–1564

    Article  PubMed  Google Scholar 

  • Garfinkel D, Zur-Gil S, Ben-Israel J (2007) The war against polypharmacy: a new cost-effective geriatric-palliative approach for improving drug therapy in disabled elderly people. Isr Med Assoc J 9: 430–434

    PubMed  Google Scholar 

  • Gosch M, Pils K (2012) [Focusing on polypharmacy in geriatrics]. Z Gerontol Geriatr 45: 448–449

    Article  CAS  PubMed  Google Scholar 

  • Hanlon JT, Schmader KE, Samsa GP, Weinberger M, Uttech KM, Lewis IK, Cohen HJ, Feussner JR (1992) A method for assessing drug therapy appropriateness. J Clin Epidemiol 45: 1045–1051

    Article  CAS  PubMed  Google Scholar 

  • Heuberger RA (2011) The frailty syndrome: a comprehensive review. J Nutr Gerontol Geriatr 30: 315–368

    Article  PubMed  Google Scholar 

  • Heymsfield SB, Adamek M, Gonzalez MC, Jia G, Thomas DM (2014) Assessing skeletal muscle mass: historical overview and state of the art. J Cachexia Sarcopenia Muscle 5: 9–18

    Article  PubMed  PubMed Central  Google Scholar 

  • Holt S, Schmiedl S, Thürmann PA (2010) Potentially inappropriate medications in the elderly: the PRISCUS list. Dtsch Arztebl Int 107: 543–551

    PubMed  PubMed Central  Google Scholar 

  • Huffman GB (2002) Evaluating and treating unintentional weight loss in the elderly. Am Fam Physician 65: 640–650

    PubMed  Google Scholar 

  • Inouye SK (2006) Delirium in older persons. N Engl J Med 354: 1157–1165

    Article  CAS  PubMed  Google Scholar 

  • Janzek-Hawlat S, Ammenwerth E, Dorda W, Duftschmid G, Hackl W, Hörbst A, Jung M, Woertz K, Gall W (2013) The Austrian e-Medikation pilot evaluation: lessons learned from a national medication list. Stud Health Technol Inform 192: 347–351

    PubMed  Google Scholar 

  • Levey AS, Coresh J, Greene T, Marsh J, Stevens LA, Kusek JW, Van Lente F, Collaboration CKDE (2007) Expressing the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate with standardized serum creatinine values. Clin Chem 53: 766–772

    Article  CAS  PubMed  Google Scholar 

  • Lopatto J, Keith SW, Del Canale S, Templin M, Maio V (2014) Evaluating sustained quality improvements: long-term effectiveness of a physician-focused intervention to reduce potentially inappropriate medication prescribing in an older population. J Clin Pharm Ther 39: 266–271

    Article  CAS  PubMed  Google Scholar 

  • Mann E, Bohmdorfer B, Fruhwald T, Roller-Wirnsberger RE, Dovjak P, Duckelmann-Hofer C, Fischer P, Rabady S, Iglseder B (2012) Potentially inappropriate medication in geriatric patients: the Austrian consensus panel list. Wien Klin Wochenschr 124: 160–169

    Article  PubMed  Google Scholar 

  • Messerli FH, Ventura HO, Amodeo C (1985) Oslerʼs maneuver and pseudohypertension. N Engl J Med 312: 1548–1551

    Article  CAS  PubMed  Google Scholar 

  • Morandi A, McCurley J, Vasilevskis EE, Fick DM, Bellelli G, Lee P, Jackson JC, Shenkin SD, Marcotrabucchi, Schnelle J, Inouye SK, Ely EW, MacLullich A (2012) Tools to detect delirium superimposed on dementia: a systematic review. J Am Geriatr Soc 60: 2005–2013

    PubMed  PubMed Central  Google Scholar 

  • Onder G, Pedone C, Landi F, Cesari M, Della Vedova C, Bernabei R, Gambassi G (2002) Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J Am Geriatr Soc 50: 1962–1968

    Article  PubMed  Google Scholar 

  • Osterberg L, Blaschke T (2005) Adherence to medication. N Engl J Med 353: 487–497

    Article  CAS  PubMed  Google Scholar 

  • Rolland Y, Czerwinski S, Abellan Van Kan G, Morley JE, Cesari M, Onder G, Woo J, Baumgartner R, Pillard F, Boirie Y, Chumlea WM, Vellas B (2008) Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives. J Nutr Health Aging 12: 433–450

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Rubenstein LZ, Josephson KR, Wieland GD, English PA, Sayre JA, Kane RL (1984) Effectiveness of a geriatric evaluation unit. A randomized clinical trial. N Engl J Med 311: 1664–1670

    Article  CAS  PubMed  Google Scholar 

  • Simm A (2011) Geriatrics: an introduction from a gerontological point of view. Dtsch Med Wochenschr 136: 2549–2553

    Article  CAS  PubMed  Google Scholar 

  • Sommeregger U (2013) The multidimensional geriatric assessment. Z Gerontol Geriatr 46: 277–285; quiz 285–276

    Article  CAS  PubMed  Google Scholar 

  • Stevens LA, Coresh J, Schmid CH, Feldman HI, Froissart M, Kusek J, Rossert J, Van Lente F, Bruce RD, Zhang YL, Greene T, Levey AS (2008) Estimating GFR using serum cystatin C alone and in combination with serum creatinine: a pooled analysis of 3,418 individuals with CKD. Am J Kidney Dis 51: 395–406

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Thiem U (2012) Potentially inappropriate medication: the quality of pharmacotherapy in the elderly. Internist (Berl) 53: 1125–1130

    Article  CAS  Google Scholar 

  • Tjia J, Velten SJ, Parsons C, Valluri S, Briesacher BA (2013) Studies to reduce unnecessary medication use in frail older adults: a systematic review. Drugs Aging 30: 285–307

    Article  PubMed  Google Scholar 

  • van der Velde N, Meerding WJ, Looman CW, Pols HA, van der Cammen TJ (2008) Cost effectiveness of withdrawal of fall-risk-increasing drugs in geriatric outpatients. Drugs Aging 25: 521–529

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Leiter Akutgeriatrie, Salzkammergutklinikum Gmunden, Miller von Aichholzstraße 49, 4810, Gmunden, Österreich

    Peter Dovjak

Authors
  1. Peter Dovjak
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Peter Dovjak .

Editor information

Editors and Affiliations

  1. Abt. für Anästhesie und Intensivmedizin, LKH Klagenfurt Abt. für Anästhesie und Intensivmedizin, Klagenfurt, Austria

    Rudolf Likar

  2. Universität Salzburg, Naturwissenschaftliche Fakultät Universität Salzburg, Salzburg, Austria

    Günther Bernatzky

  3. Klinikum Klagenfurt am Wörthersee, Klagenfurt, Austria

    Georg Pinter

  4. LKH Klagenfurt, Klagenfurt, Austria

    Wolfgang Pipam

  5. Klagenfurt am Wörthersee, Austria

    Herbert Janig

  6. Inst. für Pathophysiologie Immunologie, Medizinische Universität Graz Inst. für Pathophysiologie Immunologie, Graz, Steiermark, Austria

    Anton Sadjak

Rights and permissions

Reprints and permissions

Copyright information

© 2017 Springer-Verlag GmbH Germany

About this chapter

Cite this chapter

Dovjak, P. (2017). Pharmakotherapie im Alter. In: Likar, R., Bernatzky, G., Pinter, G., Pipam, W., Janig, H., Sadjak, A. (eds) Lebensqualität im Alter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-53101-3_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-53101-3_5

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-53100-6

  • Online ISBN: 978-3-662-53101-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics

Search

Navigation