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Cell-Specific Aptamer Characterization

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Aptamers Selected by Cell-SELEX for Theranostics

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Abstract

The functional diversity of cell-specific aptamers has enabled their use for a broad spectrum of biomedical applications. A thorough characterization of aptamers would provide better and deeper understanding and facilitate the development of customized aptamer-based diagnostics and therapeutics with enhanced performance. In this chapter, key properties of cell-specific aptamers and their characterization are discussed.

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Authors and Affiliations

  1. Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA

    Tao Chen

  2. Center for Research at Bio/Nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center, UF Genetics Institute and McKnight Brain Institute, University of Florida, Gainesville, FL, 32611-7200, USA

    Cuichen Wu & Weihong Tan

  3. Molecular Sciences and Biomedicine Laboratory, State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Biology and College of Chemistry and Chemical Engineering, Collaborative Innovation Center for Chemistry and Molecular Medicine, Hunan University, Changsha, 410082, People’s Republic of China

    Weihong Tan

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  1. Tao Chen
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  2. Cuichen Wu
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  3. Weihong Tan
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Correspondence to Weihong Tan .

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Editors and Affiliations

  1. Department of Chemistry, Hunan University, Molecular Science and Biomedicine Laboratory, State Key Laboratory for Chemo/Bio-Sensing and Chemometrics College of Chemistry and Chemical Engineering, Changsha, China & University of Florida, Gainesville, Florida, USA

    Weihong Tan

  2. Institute of Chemistry, Chinese Academy of Sciences, Beijing, China

    Xiaohong Fang

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Chen, T., Wu, C., Tan, W. (2015). Cell-Specific Aptamer Characterization. In: Tan, W., Fang, X. (eds) Aptamers Selected by Cell-SELEX for Theranostics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-46226-3_4

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