Definition
Adenine (C5H5N5), with molecular weight 135.13, is one of the four nucleic acid bases found in DNA and RNA. Via Watson-Crick base pairing in double-stranded DNA and RNA, adenine forms two hydrogen bonds with thymine (T) and uracil (U), respectively. It is hydrolyzed to give hypoxanthine. The half-life to hydrolysis in aqueous solution at pH 7 is 1 year at 100 °C and 6 × 105 years at 0 °C. It has a UV absorption maximum at 260 nm. It has been found in the Murchison meteorite and can be synthesized in HCN polymerizations, Fischer-Tropsch-type reaction, and electric discharges acting on gas mixtures such as NH3-CH4-C2H6-H2O.
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Miyakawa, S. (2015). Adenine. In: Gargaud, M., et al. Encyclopedia of Astrobiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44185-5_31
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DOI: https://doi.org/10.1007/978-3-662-44185-5_31
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