Summary
In the majority of patients with lympho- and reticulum cell sarcomas, high numbers of B-lymphocytes were found in affected lymph nodes, but were rarely observ. d. in the peripheral blood. In chronic lymphocytic leukaemia receptor properties of B-lymphocytes were defective in several aspects. In patients with Hodgkin’s disease the relative number of both lymphocyte populations in the blood were within the normal range and in lymph node suspensions marked alterations were unusual. A preferential proliferation of T-lymphocytes, perhaps accompanied by a reduced life span, was however suggested by double labelling experiments.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Peterson, R.D.A., Cooper, M.D., Good, R.A.: The pathogenesis of immunologic deficiency diseases. Amer. J. Med. 38, 578–604 (1965).
Huber, Ch., Dworzak, E., Fink, U., Michlmayr, G., Braunsteiner, H., Huber, H.: Receptor sites for aggregated gammaglobulin (AGG) on lymphocytes in lymphoproliferative diseases. Brit. J. Haemat. (in press).
Michlmayr, G., Huber, Ch., Fink, U., Falkensammer, M., Huber, H.: T-Lymphozyten in peripherem Blut und Lymphknoten bei lymphatischen Systemerkrankungen. Schweiz. Med. Wschr. 104, 815–820 (1974).
Huber, Ch., Michlmayr, G., Falkensammer, M., Fink, U., Nedden, G., zur, Braunsteiner, H., Huber, H.: Increased proliferation of T-lymphocytes in the blood of patients with Hodgkin’s disease. Clin. exp. Immun, (submitted for publication).
Seligmann, M., Preud’homme, J.L., Brouet, J.C.: B and T cell markers in human proliferative blood diseases and primary immunodeficiences, with special reference to membrane bound immunoglobulins. Transplant. Rev. 16, 85–113 (1973).
Flad, H.D., Huber, Ch., Bremer, K., Menne, H.D., Huber, H.: Impaired recirculation of lymphocytes in chronic lymphocytic leukaemia. Eur. J. Immun. 3, 688–693 (1973).
Schick, P., Trepel, H., Theml, H., Benedek, S., Trumpp, P., Kaboth, W., Begemann, H., Fliedner, T.M.: Kinetics of lymphocytes in Hodgkin’s disease. Blut 37, 223 (1973).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1975 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Huber, H., Michlmayr, G., Huber, C. (1975). Classification of Malignant Lymphomas by Means of Membrane Markers. In: Jellinger, K., Seitelberger, F. (eds) Malignant Lymphomas of the Nervous System. Acta Neuropathologica, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08456-4_4
Download citation
DOI: https://doi.org/10.1007/978-3-662-08456-4_4
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-07208-9
Online ISBN: 978-3-662-08456-4
eBook Packages: Springer Book Archive