Abstract
The Syndrome of Multiple Organ Failure (MOFS) has been described as the sequential failure of lung, liver and kidney following injury [1–11]. Historically, the MOFS was described as a response pattern following polytrauma [1–7]. Since then, it has been described after a variety of surgical pathologies including: sepsis and septic shock, hypovolemic shock as in ruptured aneurysms, and following persistent inflammation, as in pancreatitis [8–12]. It is also felt to be the most common reason associated with surgical intensive care units (SICU) stays over 5 days and to be the major cause of death in these patients today [12, 13].
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References
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Cerra, F.B., Negro, F., Eyer, S. (1990). Multiple Organ Failure Syndrome: Patterns and Effect of Current Therapy. In: Vincent, J.L. (eds) Update 1990. Update in Intensive Care and Emergency Medicine, vol 10. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84125-5_2
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DOI: https://doi.org/10.1007/978-3-642-84125-5_2
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