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A New Adjuvant Treatment with PolyadenyliC-Polyuridylic Acid in Operable Breast Cancer

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Adjuvant Therapies of Cancer

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 80))

Summary

Adjuvant treatment with polyadenylic-polyuridylic acid poly A-poly U was tested in 300 patients with operable breast cancer who had all received the same locoregional treatment. They were randomized into two groups; 155 patients receiving 30 mg poly A-poly U i.v. once a week for 6 weeks and 145 controls. Overall survival was significantly improved in the poly A-Poly U group (P<0.05). The most striking difference (P < 0.03) was observed in the group of positive node patients, who had a 5-year relapse-free actuarial survival rate of 71% versus 47% in the controls.

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© 1982 Springer-Verlag Berlin · Heidelberg

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Lacour, F. et al. (1982). A New Adjuvant Treatment with PolyadenyliC-Polyuridylic Acid in Operable Breast Cancer. In: Mathé, G., Bonadonna, G., Salmon, S. (eds) Adjuvant Therapies of Cancer. Recent Results in Cancer Research, vol 80. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81685-7_32

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  • DOI: https://doi.org/10.1007/978-3-642-81685-7_32

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81687-1

  • Online ISBN: 978-3-642-81685-7

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