Abstract
When, with what symptoms and how schizophrenia really begins, and how this beginning can be distinguished from already existing deficits or antecedents are all interesting questions. They arise following the papers of Crow et al. and Walker et al. on the antecedents of psychosis. Kraepelin (1909) and Bleuler (1911) had already observed that the disease rarely begins without non-specific symptoms in advance. Kraepelin (1909) mentioned, for instance, “small changes in emotional life, irritability, loss of interest, overactivity and poor concentration.” DeLisi et al. (1986) and Huber and Gross (1989) recently expressed the expectation that the elucidation of the prodromal phase might provide a new understanding of the psychopathology and etiology of schizophrenia.
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References
an der Heiden W, Krumm B, Müller S, Weber I, Biehl H (1994) Mannheimer Langzeitstudie der Schizophrenie: erste Analysen zum Outcome 14 Jahre nach Erstbehandlung (submitted)
Andreasen NC, Olsen SA (1982) Negative v. positive schizophrenia. Arch Gen Psychiatry 39: 789–794
Andreasen NC, Flaum M, Arndt S, Alliger R, Swayze VW (1991) Positive and negative symptoms: assessment and validity. In: Marneros A, Andreasen NC, Tsuang NT (eds) Negative versus positive schizophrenia. Springer, Berlin Heidelberg New York, pp 28–51
Angermeyer MC, Kühn L, Goldstein JM (1990) Gender and the course of schizophrenia: Differences in treated outcomes. Schizophr Bull 2:293–307
Biehl H, Maurer K, Sehubart C, Krumm B, Jung E (1986) Prediction of outcome and utilization of medical services in a prospective study of first onset schizophrenics — results of a prospective 5-year follow-up study. Eur Arch Psychiatry Neurol Sci 236:139–147
Bleuler E (1911) Dementia praecox oder Gruppe der Schizophrenien. In: Aschaffenburg G (ed) Handbuch der Psychiatrie. Deuticke, Leipzig, pp 1–420
Carpenter WT, Buchanan RW, Krkpatrick B et al (1991) Negative symptoms: a critique of current approaches. In: Marneros A, Andreasen NC, Tsuang MT (eds) Springer, Berlin Heidelberg New York, pp 126–133
Conrad K (1958) Die beginnende Schizophrenie. Versuch einer Gestaltanalyse des Wahns. Thieme, Stuttgart
Crow TJ (1980) Positive and negative schizophrenic symptoms and the role of dopamine. Br J Psychiatry 137:383–386
DeLisi LE, Crow TJ, Hirsch SR (1986) The third biannual winter workshop on schizophrenia. Arch Gen Psychiatry 43:706–711
Dilling H, Weyerer S (1987) Social class and mental disorders: Results from upper bavarian studies. In: Angermeyer MC (ed) From social class to social stress. Springer, Berlin Heidelberg New York, pp 46–63
Docherty JP, Van Kämmen DP, Siris SG, Marder SR (1978) Stages of onset of schizophrenic psychosis. Am J Psychiatry 135:420–426
Dohrenwend BP (1987) Social class and mental disorder: the stress/selection issue. In: Angermeyer MC (ed) From social class to social stress. Springer, Berlin Heidelberg New York, pp 106–116
Goldstein JM, Kreisman D (1988) Gender, family environment and schizophrenia. Psychol Med 18:861–872
Häfner H, an der Heiden W (1986) The contribution of European case registers to research on schizophrenia. Schizophr Bull 12:26–50
Häfner H, Maurer K (1993a) Methodenprobleme der Erforschung von Krankheitsbeginn und Frühverlauf am Beispiel Schizophrenie. Fund Psychiatr 7:1–12
Häfner H, Maurer K (1993b) Epidemiology of positive and negative symptoms in schizophrenia. In: Shriqui CL, Nasrallah HA (eds) Contemporary issues in the treatment of schizophrenia. American Psychiatric Press, Washington DC
Häfner H, Nowotny B (1993) When and how does schizophrenia lead to social deficits? Paper for post-congress of 1993 WFMH World Congress, Tokyo
Häfner H, Riecher A, Maurer K, Meissner S, Schmidtke A, Fätkenheuer B, Löffler W, an der Heiden W (1990) Ein Instrument zur retrospektiven Einschätzung des Erkrankungsbeginns bei Schizophrenie (IRAOS) Entwicklung und Ergebnisse. Z Klin Psychol 19:230–255
Häfner H, Riecher A, Maurer K, Fätkenheuer B, Löffler W, an der Heiden W, Münk-Jorgensen P, Strömgren E (1991) Geschlechtsunterschiede bei schizophrenen Erkrankungen. Fortschr Neurol Psychiatr 59:343–360
Häfner H, Riecher-Rössler A, Hambrecht M, Maurer K, Meissner S, Schmidtke A, Fätkenheuer B, Löffler W, an der Heiden W (1992) IRAOS: an instrument for the assessment of onset and early course of schizophrenia. Schizophr Res 6:209–223
Häfner H, Maurer K, Löffler W, Riecher-Rössler A (1993) The influence of age and sex on the onset and early course of schizophrenia. Br J Psychiatry 162:80–86
Hamera EK, Peterson KA, Young LM, Schaumlöffel MM (1992) Symptom monitoring in schizophrenia: potential for enhancing self-care. Arch Psychiatr Nursing 6:324–330
Heinrichs DW, Carpenter WT Jr (1985) Prospective study of prodromal symptoms in schizophrenic relapse. Am J Psychiatry 142:371–373
Herz MI, Melville C (1980) Relapse in schizophrenia. Am J Psychiatry 137:801–805
Herz MI, Szymanski HV, Simon JC (1982) Intermittent medication for stable schizophrenic outpatients: an alternative to maintenance medication. Am J Psychiatry 139:918–922
Hirsch SR, Jolley AG (1989) The dysphoric syndrome in schizophrenia and its implications for relapse. Br J Psychiatry 155[Suppl 5]:46–50
Hollingshead AB, Redlich FC (1958) Social class and mental illness. Wiley, New York
Huber G, Gross G (1989) The concept of basic symptoms in schizophrenia and schizoaffective psychoses. Ree Prog Med 80:646–652
Jung E, Krumm B, Biehl H, Maurer K, Bauer-Schubart C (1989) DAS-M: Mannheimer Skala zur Einschätzung Sozialer Behinderung. Beltz, Weinheim
Kay SR, Fiszbein A, Lindenmayer J-P et al (1986) Positive and negative syndromes in schizophrenia as a function of chronicity. Acta Psychiatr Scand 74:507–518
Klosterkötter J (1992) Die Entwicklung der schizophrenen Symptome ersten Ranges. Fund Psychiatr 6:81–94
Kraepelin E (1896) Psychiatrie. Ein Lehrbuch für Studierende und Aerzte. Barth, Leipzig
Kraepelin E (1909) Psychiatrie. Barth, Leipzig
Kumar S, Thara R, Rajkumar S (1989) Coping with symptoms of relapse in schizophrenia. Eur Arch Psychiatr Neurol Sci 239:213–215
Langfeldt GE (1956) Prognosis in schizophrenia. Acta Psychiatr Scand Suppl 110
Marder SR, Van Putten T, Mintz J, Lebeil M, McKenzie J, Faltico G (1984) Maintenance therapy in schizophrenia: new findings. In: Kane JM (ed) Drug maintenance strategies in schizophrenia. American Psychiatric Press, Washington
Marder SR, Van Putten T, Mintz J, McKenzie J, May PRA (1987) Low and conventional-dose maintenance therapy with fluphenazine deconoate. Arch Gen Psychiatry 44:518–521
Mauz F (1930) Die Prognostik der endogenen Psychosen. Thieme, Leipzig
Murray RM, Lewis SW (1987) Is schizophrenia a neurodevelopmental disorder? Br Med J 295:681–682
Nowotny B, Häfner H (1994) Die beginnende Schizophrenie als Einbruch in die soziale Biographie — Folgen für soziale Behinderung versus soziale Wiederanpassung. Fund Psychiatr (in press)
Pogue-Geile MF, Harrow M (1985) Negative symptoms in schizophrenia: their longitudinal and prognostic importance. Schizophr Bull 11:427–439
Pogue-Geile MF, Zubin J (1988) Negative symptomatology and schizophrenia: a cenceptual and empirical review. Int J Ment Health 16:3–45
Rey ER, Beck U, Mörstadt P, Oldigs J (1987) Experimentelle Untersuchungen zur Aufmerksamkeitsstörung Schizophrener. In: Gerber WD, Miltner W, Mayer K (eds) Verhaltensmedizin: Ergebnisse und Perspektiven interdisziplinärer Forschung. VCH, Weinheim
Rey E-R, Bailer J, Laubenstein D, Grahoff U (1992) Einfluß von prämorbider Anpassung, sozialen Netzwerkparametern und sozialer Unterstützung auf die Negativsymptomatik ersterkrankter Schizophrener. Verhaltenstherapie 2:300–308
Riecher-Rössler A, Häfner H, Maurer K, Stummbaum M, Schmidt R (1992) Schizophrenic symptomatology varies with serum estroadiol levels during menstrual cycle. Schizophr Res 6(special issue): 114
Riecher-Rössler A, Häfner H, Stumbaum M, Schmidt R (1994) Can estradiol modulate schizophrenic symptomatology? Schizophr Bull 20 (in press)
Salokangas RKR (1983) Prognostic implications of the sex of schizophrenic patients. Br J Psychiatry 142:145–151
Salokangas RKR, Stengard E (1990) Gender and short-term outcome in schizophrenia. Schizophr Res 3:333–345
Statistisches Bundesamt (1987) Datenreport 3
Subotnik KL, Nuechterlein KH (1988) Prodromal signs and symptoms of schizophrenic relapse. J Abnorm Psychol 97:405–412
Tarrier N, Barrowclough C, Bamrah JS (1991) Prodromal signs of relapse in schizophrenia. Soc Psychiatry Psychiatr Epidemiol 26:157–161
Thurm I, Häfner H (1987) Perceived vulnerability, relapse risk and coping in schizophrenia. An explorative study. Eur Arch Psychiatry Neurol Sci 237:46–53
Wattie BS, Kedward HB (1985) Gender differences in living conditions found among male and female schizophrenic patients on a follow-up study. International Journal of Social Psychiatry 31(3):205–216
WHO AS (1988) Psychiatric disability assessment schedule. World Health Organization, Geneva
Wing JK (1978) Reasoning about madness. Oxford University Press Oxford
Zedlick D, Maurer K, Löffler W, Riecher-Rössler A, Häfner H (1993) Der Frühverlauf der Schizophrenie und seine Beziehung zu Alter, Geschlecht und Diagnose bei stationärer Erstaufnahme. Neuropsychiatrie 7:183–196
Zigler E, Levine J (1981) Premorbid competence in schizophrenia: what is being measured. J Consult Clin Psychol 90:458–467
Zubin J, Spring B (1977) Vulnerability — a new view of schizophrenia. J Abnorm Psychol 86: 103–126
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Häfner, H. et al. (1995). Onset and Early Course of Schizophrenia. In: Häfner, H., Gattaz, W.F. (eds) Search for the Causes of Schizophrenia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79429-2_3
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DOI: https://doi.org/10.1007/978-3-642-79429-2_3
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