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Ribosomal RNA Metabolism in Macrophages

  • Chapter
Macrophage Biology and Activation

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 181))

Abstract

Macrophages are ubiquitous cells critical for host defense (Wiltrout and Varesio 1987; Varesio 1985b). Metchnikoff’s original report in the late nineteenth century first suggested that phagocytes are the body’s prime detectors of foreign invaders; the functions of macrophages have since been delineated, initially at a cellular level and more recently at a molecular level.

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Authors and Affiliations

  1. Immunobiology Section, Laboratory of Molecular Immunoregulation, Biological Response Modifiers Program, National Cancer Institute, Frederick Cancer Research Development Center, Frederick, MD, 21702-1201, USA

    L. Varesio

  2. McGill Center for the Study of Host Resistance, Montreal General Hospital, Montreal, Quebec, Canada

    D. Radzioch

  3. Instituto di Ricerche Farmacologiche Mario Negri, Milan, Italy

    B. Bottazzi

  4. Biological Carcinogenesis and Development Program, PRI/DynCorp, Frederick Cancer Research Development Center, Frederick, MD, 21702-1201, USA

    G. L. Gusella

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  1. L. Varesio
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  2. D. Radzioch
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  3. B. Bottazzi
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  4. G. L. Gusella
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Editors and Affiliations

  1. University of Kansas Cancer Ctr., Kansas City, KA, 66160-7312, USA

    Stephen W. Russell (Wilkinson Distinguished Professor and Director) (Wilkinson Distinguished Professor and Director)

  2. Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE, UK

    Siamon Gordon

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Varesio, L., Radzioch, D., Bottazzi, B., Gusella, G.L. (1992). Ribosomal RNA Metabolism in Macrophages. In: Russell, S.W., Gordon, S. (eds) Macrophage Biology and Activation. Current Topics in Microbiology and Immunology, vol 181. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77377-8_8

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