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Toxic Effects of Carbon Tetrachloride During Short and Long Term Ethanol Intake in Rats

  • Conference paper
Recent Developments in Toxicology: Trends, Methods and Problems

Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 14))

  • 117 Accesses

Abstract

In continuing the investigations into the influence of ethanol pretreatment on the toxic effects of a single CCl4 dose (Kniepert et al 1990), changes following the repeated simultaneous administration of ethanol and CCl4 were studied.

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References

  • Bell AN, Young RA, Lockard VG, Mehendale HM (1988) Protection of chlordeconepotentiated carbon tetrachloride hepatotoxicity and lethality by partial hepatectomy. Arch Toxicol 61:392–405

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  • Kniepert E, Seffner W (1989) Histological and histometrical changes of liver damage in rats after treatment with ethanol and carbon tetrachloride. Exp Pathol 36: 185–188

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  • Kniepert E, Siegemund A, Gorisch V (1990) Influence of ethanol pretreatment of differing duration on toxic effects of carbon tetrachloride in rats. Biomed Biochim Acta 49:1097–1102

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  • Zimmerman HJ (1983) Hepatotoxic Evaluation Methodology. In: Diagnostic Procedures in the Evaluation of Hepatic Diseases. Ed. Beker S, New York, Alan R Liss, 159–194

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Author information

Authors and Affiliations

  1. Institutes of Pharmacology and Toxicology, University Leipzig, Härtelstraße 16-18, 7010, Leipzig, Germany

    E. Kniepert & V. Görisch

  2. Clinical Chemistry and Laboratory Diagnostic, University Leipzig, Härtelstraße 16-18, 7010, Leipzig, Germany

    A. Siegemund

  3. Pathology, Department of Medicine, University Leipzig, Härtelstraße 16-18, 7010, Leipzig, Germany

    M. Rosenkranz

Authors
  1. E. Kniepert
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  2. A. Siegemund
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  3. M. Rosenkranz
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  4. V. Görisch
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Editor information

Editors and Affiliations

  1. Department of Pharmacology and Therapeutics, Trinity College, University of Dublin, Dublin 2, Ireland

    Philip L. Chambers  & Claire M. Chambers  & 

  2. Institut für Pharmakologie und Toxikologie, Universität Leipzig, Universitätsbereich Medizin, Härtelstraße 16-18, O-7010, Leipzig, Germany

    Wolf Diether Wiezorek

  3. Veterinärmedizinische Fakultät, Institut für Pharmakologie, Pharmazie und Toxikologie, Universität Leipzig, Zwickauer Straße 55, O-7010, Leipzig, Germany

    Siegfried Golbs

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© 1991 Springer-Verlag Berlin Heidelberg

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Kniepert, E., Siegemund, A., Rosenkranz, M., Görisch, V. (1991). Toxic Effects of Carbon Tetrachloride During Short and Long Term Ethanol Intake in Rats. In: Chambers, P.L., Chambers, C.M., Wiezorek, W.D., Golbs, S. (eds) Recent Developments in Toxicology: Trends, Methods and Problems. Archives of Toxicology, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74936-0_55

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  • DOI: https://doi.org/10.1007/978-3-642-74936-0_55

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51422-0

  • Online ISBN: 978-3-642-74936-0

  • eBook Packages: Springer Book Archive

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