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Activation of CD4-Positive T Cells by Polysaccharide Fractions Isolated from the Cupressaceae Thuja occidentalis L. (Arborvitae).

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Modern Trends in Human Leukemia VIII

Part of the book series: Haematology and Blood Transfusion / Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 32))

Abstract

Various mitogens have been described which act on different subpopulations of mouse and/or human peripheral lymphocytes. In recent years it has been mainly Japanese and German research teams that have isolated polysaccharide fractions with immunomodulative properties [1–3, 17]. In addition to fungal polysaccharides such as lentinan, schizophyllan, and PSK polysaccharide, which are basically in the experimental step of clinical use [6, 10, 13], the focus of attention has mainly been on plants belonging to the asteracean family, such as Echinacea purpurea and E. angustifolia, where an increase in granulocyte phagocytosis is observable. Thuja occidentalis L., a Cupressaceae, has hardly been investigated up till now.

This study has been supported by the Karl-und Veronika Carstens-Stiftung im Stifterver-band für die Deutsche Wissenschaft

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Author information

Authors and Affiliations

  1. Department of Clinical Chemistry, Medical University Clinic, UKE, Martinistraße 52, D-2000, Hamburg, Germany

    Sven H. Gohla, Silke Schrum, Helga Soltau & Rolf D. Neth

  2. Department of Clinical Chemistry, Medical University Clinic, Pauwelsstraße, D-5100, Aachen, Germany

    Hans-Dieter Haubeck

Authors
  1. Sven H. Gohla
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  2. Hans-Dieter Haubeck
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  3. Silke Schrum
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  4. Helga Soltau
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  5. Rolf D. Neth
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Editor information

Editors and Affiliations

  1. Medizinische Klinik, Abteilung für klinische Chemie, Universitäts-Krankenhaus Eppendorf, Martinistraße 52, 2000, Hamburg 20, Germany

    Rolf Neth

  2. Laboratory of Tumor Cell Biology, National Cancer Institute, 20892, Bethesda, MD, USA

    Robert C. Gallo

  3. Chester Beatty Laboratories, Leukemia Research Fund Centre, Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK

    Melvyn F. Greaves

  4. Abteilung Pädiatrie II, Universitätskinderklinik und Poliklinik Ulm, Prittwitzstr. 43, 7900, Ulm, Germany

    Gerhard Gaedicke

  5. Universität Ulm, Prittwitzstr. 43, 7900, Ulm, Germany

    Gerhard Gaedicke

  6. Labor für Hautimmunologie, Bioverträglichkeit-Immunologie, Paul-Gerson-Unna-Forschungszentrum, Beiersdorf-AG, Unnastr. 48, 2000, Hamburg 20, Germany

    Sven Gohla

  7. Heinrich-Pette-Institut für Experimentelle Virologie und Immunologie, Martinistr. 52, 2000, Hamburg 20, Germany

    Klaus Mannweiler

  8. Abteilung Hämatologie und Onkologie, Kinderklinik und Poliklinik der Westfälischen Wilhelms-Universität, Albert-Schweitzer-Str. 33, 4400, Münster, Germany

    Jörg Ritter

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© 1989 Springer-Verlag Berlin Heidelberg

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Gohla, S.H., Haubeck, HD., Schrum, S., Soltau, H., Neth, R.D. (1989). Activation of CD4-Positive T Cells by Polysaccharide Fractions Isolated from the Cupressaceae Thuja occidentalis L. (Arborvitae).. In: Neth, R., et al. Modern Trends in Human Leukemia VIII. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 32. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74621-5_47

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  • DOI: https://doi.org/10.1007/978-3-642-74621-5_47

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50967-7

  • Online ISBN: 978-3-642-74621-5

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