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Brown Adipose Tissue is a Target Tissue in 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Induced Toxicity

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Toxic Interfaces of Neurones, Smoke and Genes

Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 9))

Abstract

This paper demonstrates by electron microscopy that interscapular brown adipose tissue (IBAT) is a target tissue of 2,3,7,8-tetrachlorodibenzop-dioxin (TCDD) in rats. Because of the known importance of IBAT in energy metabolism, it is suggested that brown adipose tissue may be a major target tissue in the toxicity of TCDD.

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References

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Author information

Authors and Affiliations

  1. Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS, 66103, USA

    K. Rozman

  2. Abteilung für Toxikologie, Gesellschaft für Strahlen- und Umweltforschung München mbH, D-8042, Neuherberg, Germany

    K. Rozman

  3. Wilbur G. Malcolm Toxicology Laboratories, Medical Research Division, American Cyanamid Company, Pearl River, New York, 10965, USA

    B. Strassle & M. J. Iatropoulos

Authors
  1. K. Rozman
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  2. B. Strassle
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  3. M. J. Iatropoulos
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Editor information

Editors and Affiliations

  1. Department of Pharmacology and Therapeutics, Trinity College, University of Dublin, Dublin 2, Ireland

    Claire M. Chambers  & Philip L. Chambers  & 

  2. Department of Environmental Hygiene and Toxicology, National Public Health Institute, P.O.B. 95, SF 70701, Kuopio, Finland

    Jouko Tuomisto

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© 1986 Springer-Verlag

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Rozman, K., Strassle, B., Iatropoulos, M.J. (1986). Brown Adipose Tissue is a Target Tissue in 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) Induced Toxicity. In: Chambers, C.M., Chambers, P.L., Tuomisto, J. (eds) Toxic Interfaces of Neurones, Smoke and Genes. Archives of Toxicology, vol 9. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71248-7_68

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  • DOI: https://doi.org/10.1007/978-3-642-71248-7_68

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-16589-7

  • Online ISBN: 978-3-642-71248-7

  • eBook Packages: Springer Book Archive

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