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A Model Scheme of Hematopoietic Cell Differentiation Based on Multiple Marker Analysis of Leukemia-Lymphomas: T Cell Lineage

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Modern Trends in Human Leukemia VI New Results in Clinical and Biological Research Including Pediatric Oncology

Abstract

The analysis of human leukocyte differentiation antigens has been greatly facilitated by studies of leukemia and lymphoma cells [1]. Because of the two characteristics common to both leukemia and lymphoma, i. e., single clonal cell population of respective hematopoietic cell type and arrested differentiation profile in each case, studies of multiple marker analysis and in vitro induced cellular differentiation system by a variety of chemical and natural inducers have continued to provide steady progress in this area of knowledge. Furthermore, recent advances in molecular biology relative to cytogenetic nonrandom abnormalities in the hematopoietic malignancies provide further insight into pathophysiology of these diseases [2].

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© 1985 Springer-Verlag Berlin Heidelberg

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Minowada, J. et al. (1985). A Model Scheme of Hematopoietic Cell Differentiation Based on Multiple Marker Analysis of Leukemia-Lymphomas: T Cell Lineage. In: Neth, R., Gallo, R.C., Greaves, M.F., Janka, G. (eds) Modern Trends in Human Leukemia VI New Results in Clinical and Biological Research Including Pediatric Oncology. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70385-0_87

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  • DOI: https://doi.org/10.1007/978-3-642-70385-0_87

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15329-0

  • Online ISBN: 978-3-642-70385-0

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