Abstract
Stoichiometric network analysis [1] and sensitivity analysis [2] are combined to yield a computational tool for the study of chemical reaction networks. Sensitivity of chemical oscillations to parameter perturbations is studied via this combined approach. It is shown that quantitative, physical insights are gained from network sensitivity analysis that are not available either from stoichiometric network analysis or the ordinary rate-constant-based sensitivity analysis.
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References
B. L. Clarke, Adv. Chem. Phys. 43, 1 (1980).
P. M. Frank, Introduction to System Sensitivity Theory, Academic Press, NY (1978). 2 b) E. P. Dougherty, J.-T. Hwang and H. Rabitz 71, 1794 (1979).
R. Larter, J. Phys. Chem. 87, 3114 (1983).
B. L. Clarke in Proc. of Symp. on Chemical Applications of Topology and Graph Theory, R. Bruce King, ed., Elsevier (1983).
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© 1984 Springer-Verlag Berlin Heidelberg
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Larter, R., Clarke, B.L. (1984). Chemical Reaction Network Sensitivity Analysis. In: Horsthemke, W., Kondepudi, D.K. (eds) Fluctuations and Sensitivity in Nonequilibrium Systems. Springer Proceedings in Physics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-46508-6_24
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DOI: https://doi.org/10.1007/978-3-642-46508-6_24
Publisher Name: Springer, Berlin, Heidelberg
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