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Genetic Vulnerability to Eating Disorders and Substance Use Disorders

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Eating Disorders, Addictions and Substance Use Disorders

Abstract

It is well established that there is substantial comorbidity between eating disorders and substance use disorders. However, it is unclear why these two disorders frequently co-occur. It has been hypothesized that the two disorders may share a common etiology, which could be genetic in nature. There is ample evidence that the eating disorders, specifically anorexia nervosa and bulimia nervosa, and a variety of substance use disorders have a genetic component, yet little research has explored whether these genetic factors are shared. This chapter reviews the current empirical literature indicating that anorexia nervosa and bulimia nervosa and substance use disorders are influenced by genetic factors, as well as preliminary findings exploring whether these disorders indeed share a genetic architecture. We close with suggestions for future research to further elucidate the shared genetic risk between eating disorders and substance use disorders.

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Authors and Affiliations

  1. Department of Psychiatry, University of North Carolina at Chapel Hill, CB #7160, 101 Manning Drive, Chapel Hill, NC, 27599-7160, USA

    Jessica H. Baker

  2. Department of Psychiatry and Midwest Alcoholism Research Center, Washington University School of Medicine, St. Louis, MO, USA

    Melissa A. Munn-Chernoff

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Correspondence to Jessica H. Baker .

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  1. Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA

    Timothy D. Brewerton

  2. Psychiatry and Behavioral Neurosciences, University of South Florida, Bloomfield Hills, Michigan, USA

    Amy Baker Dennis

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Baker, J.H., Munn-Chernoff, M.A. (2014). Genetic Vulnerability to Eating Disorders and Substance Use Disorders. In: Brewerton, T., Baker Dennis, A. (eds) Eating Disorders, Addictions and Substance Use Disorders. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45378-6_5

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  • DOI: https://doi.org/10.1007/978-3-642-45378-6_5

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