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Bipolar Disorder

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Encyclopedia of Psychopharmacology
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Synonyms

Bipolar illness; Manic-depressive illness

Definition

The unique phase of bipolar disorder is mania. In many ways mania is the opposite of depression and is characterized by elevated mood or euphoria, overactivity with a lack of need for sleep, and increased optimism that usually becomes so severe that judgment is impaired. Other drives such as sexual desire are also enhanced: manic patients are disinhibited in their speech about sexual matters, making jokes or talking about subjects not normally allowed in their culture. Manic patients are sometimes disinhibited in their sexual actions as well and may endanger their marriages or relationships as a result. A key point is that manic behavior is distinct from a patient’s usual personality, but may have a gradual onset over weeks or months before the syndrome is full blown. In the absence of effective treatment, manic episodes could last months and years, although ultimately most are self-limited. Even after a long manic episode...

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References

  • American Psychiatric Association (2002) Practice guideline for the treatment of patients with bipolar disorder (revision). Am J Psychiatry 159(4 Suppl):1–50

    Google Scholar 

  • Aubry JM, Ferrero R et al (2007) Pharmacotherapy of bipolar disorders. Wiley, West Sussex

    Google Scholar 

  • Belmaker RH (2004) Bipolar disorder. N Engl J Med 351(5):476–486

    CAS  PubMed  Google Scholar 

  • Belmaker RH (2007) Treatment of bipolar depression. N Engl J Med 356(17):1771–1773

    CAS  PubMed  Google Scholar 

  • Belmaker RH, Agam G (2008) Major depressive disorder. N Engl J Med 358(1):55–68

    CAS  PubMed  Google Scholar 

  • Cousins DA, Young AH (2007) The armamentarium of treatments for bipolar disorder: a review of the literature. Int J Neuropsychopharmacol 10(3):411–431

    CAS  PubMed  Google Scholar 

  • Fountoulakis KN, Vieta E (2008) Treatment of bipolar disorder: a systematic review of available data and clinical perspectives. Int J Neuropsychopharmacol 11(7):999–1029

    CAS  PubMed  Google Scholar 

  • Goodwin FK, Fireman B et al (2003) Suicide risk in bipolar disorder during treatment with lithium and divalproex. JAMA 290(11):1467–1473

    CAS  PubMed  Google Scholar 

  • Lepkifker E, Sverdlik A, Iancu I, Ziv R, Segev S, Kotler M (2004) Renal insufficiency in long-term lithium treatment. J Clin Psychiatry 65:850–856

    Google Scholar 

  • McKnight RF, Adida M et al (2012) Lithium toxicity profile: a systematic review and meta-analysis. Lancet 379(9817):721–728

    CAS  PubMed  Google Scholar 

  • Osher Y, Bersudsky Y, Belmaker RH (2010) The new lithium clinic. Neuropsychobiology 62(1):17–26

    PubMed  Google Scholar 

  • Post RM, Ketter TA et al (1996) Rational polypharmacy in the bipolar affective disorders. Epilepsy Res Suppl 11:153–180

    CAS  PubMed  Google Scholar 

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Correspondence to Robert H. Belmaker .

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© 2015 Springer-Verlag Berlin Heidelberg

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Belmaker, R.H. (2015). Bipolar Disorder. In: Stolerman, I.P., Price, L.H. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36172-2_364

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