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Integration of Biomolecular Interaction Data in a Genomic and Proteomic Data Warehouse to Support Biomedical Knowledge Discovery

  • Conference paper
Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB 2011)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 7548))

Abstract

The growing available genomic and proteomic information gives new opportunities for novel research approaches and biomedical discoveries through effective data management and analysis support. Integration and comprehensive evaluation of available controlled data can highlight information patterns leading to unveil new biomedical knowledge. For this purpose, the University Politecnico di Milano, is developing a software framework to create and maintain a Genomic and Proteomic Data Warehouse (GPDW) that integrates information from many data sources on the basis of a conceptual data model that relates molecular entities and biomedical features.

Here we illustrate and discuss the extension of framework for integrating biomolecular interaction data in the GPDW. The comprehensive and mining of the reliable interaction data together with the other biomolecular information in the GPDW constitutes a powerful computational support for novel biomedical knowledge discoveries.

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Authors and Affiliations

  1. Dipartimento di Elettronica e Informazione, Politecnico di Milano, Piazza Leonardo Da Vinci 32, 20133, Milano, Italy

    Arif Canakoglu, Giorgio Ghisalberti & Marco Masseroli

Authors
  1. Arif Canakoglu
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  2. Giorgio Ghisalberti
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  3. Marco Masseroli
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Editor information

Editors and Affiliations

  1. Department of Clinical Sciences and Community, University of Milan, via Vanzetti, 5, 20133, Milan, Italy

    Elia Biganzoli  & Federico Ambrogi  & 

  2. Dpto. de Lenguajes y Sistemas Informáticos (LSI), Universidad Politecnica de la Catalunya, C/Jordi Girona 1-3, Ed. Omega, 08034, Barcelona, Spain

    Alfredo Vellido

  3. Department of Mathematics and Information Sciences, University of Salerno, Via Ponte don Melillo, 84084, Fisciano, SA, Italy

    Roberto Tagliaferri

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Canakoglu, A., Ghisalberti, G., Masseroli, M. (2012). Integration of Biomolecular Interaction Data in a Genomic and Proteomic Data Warehouse to Support Biomedical Knowledge Discovery. In: Biganzoli, E., Vellido, A., Ambrogi, F., Tagliaferri, R. (eds) Computational Intelligence Methods for Bioinformatics and Biostatistics. CIBB 2011. Lecture Notes in Computer Science(), vol 7548. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35686-5_10

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  • DOI: https://doi.org/10.1007/978-3-642-35686-5_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-35685-8

  • Online ISBN: 978-3-642-35686-5

  • eBook Packages: Computer ScienceComputer Science (R0)

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