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Molecular Mechanisms for the Initiation and Maintenance of Long-Term Memory Storage

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Two Faces of Evil: Cancer and Neurodegeneration

Part of the book series: Research and Perspectives in Alzheimer's Disease ((ALZHEIMER))

Abstract

As a result of advances in cellular, molecular and systems biology the mechanisms underlying the initial storage, maintenance and recall of memories are now beginning to be understood. To obtain these insights several model systems and methodologies have been used. Here we briefly summarize this recent progress based on study of two model systems, the gill-withdrawal reflex of Aplysia and hippocampal based spatial memory storage in the mouse.

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Authors and Affiliations

  1. Department of Neuroscience, Howard Hughes Medical Institute, Columbia University, New York, NY, 10032, USA

    Eric Kandel

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  1. Sathyanarayanan Puthanveettil
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  2. Eric Kandel
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Correspondence to Eric Kandel .

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  1. , Department of Pathology and Laboratory M, The Children's Hospital of Philadelphia, Civic Center Boulevard 3501, Philadelphia, 19104, Pennsylvania, USA

    Thomas Curran

  2. Fondation IPSEN, Quai Georges Gorse 65, Boulogne-Billancourt Cedex, 92650, France

    Yves Christen

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Puthanveettil, S., Kandel, E. (2011). Molecular Mechanisms for the Initiation and Maintenance of Long-Term Memory Storage. In: Curran, T., Christen, Y. (eds) Two Faces of Evil: Cancer and Neurodegeneration. Research and Perspectives in Alzheimer's Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16602-0_13

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