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Total Synthesis of Bioactive Peptides and Depsipeptides from Marine Opisthobranch Molluscs

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Molluscs

Part of the book series: Progress in Molecular and Subcellular Biology ((MMB,volume 43))

Abstract

This chapter covers the synthetic aspects of both linear or cyclic peptides and depsipeptides isolated from opisthobranch molluscs. In many cases, synthetic effort not only determined the absolute stereostructure of these compounds but also made it possible to supply sufficient amounts for the evaluation of pharmacological activities. A summary of the synthetic work associated with each compound is reported after a short description of its natural source and biological properties. Discussion in the text concentrates on key reactions and synthetic efficiency.

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Author information

Authors and Affiliations

  1. Dipartimento di Chimica, Università di Salerno, Via S. Allende, 84081, Baronissi (Salerno), Italy

    Aldo Spinella

Authors
  1. C. Della Monica
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  2. G. Della Sala
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  3. F. De Riccardis
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  4. I. Izzo
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  5. Aldo Spinella
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Editor information

Editors and Affiliations

  1. Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Via Campi Flegrei, 34, 80078, Pozzuoli (Naples), Italy

    Guido Cimino  & Margherita Gavagnin  & 

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© 2006 Springer-Verlag Berlin Heidelberg

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Della Monica, C., Della Sala, G., De Riccardis, F., Izzo, I., Spinella, A. (2006). Total Synthesis of Bioactive Peptides and Depsipeptides from Marine Opisthobranch Molluscs. In: Cimino, G., Gavagnin, M. (eds) Molluscs. Progress in Molecular and Subcellular Biology, vol 43. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-30880-5_15

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