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Retinopathy of Prematurity

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Retinal Vascular Disease

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Abstract

Retinopathy of prematurity (ROP) was first noted in the late 1940s in preterm infants and described as retrolental fibroplasia, a total retinal detachment seen as white mass behind the lens. The disease was subsequently associated with excessive oxygen use [12, 14, 52]. Oxygen supplementation was curtailed with a decrease in ROP but with an increase in cerebral palsy and death. Supplemental oxygen is now delivered to premature infants to maintain adequate blood levels, but it is monitored carefully [37].

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References

  1. Adamis AP, Shima DT, Yeo KT, Yeo TK, Brown LF, Berse B, D’Amore PA, Folkman J (1993) Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem Biophys Res Commun 193:631–638

    Article  PubMed  CAS  Google Scholar 

  2. Adamis AP, Miller JW, Bernal MT, D’Amico DJ, Folkman J, Yeo TK, Yeo KT (1994) Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Am J Ophthalmol 118:445–450

    PubMed  CAS  Google Scholar 

  3. Adamis AP, Shima DT, Tolentino MJ, Gragoudas ES, Ferrara N, Folkman J, D’Amore PA, Miller JW (1996) Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate.Arch Ophthalmol 114:66–71

    PubMed  CAS  Google Scholar 

  4. Aiello LP, Avery RL, Arrigg PG, Keyt BA, Jampel HD, Shah ST, Pasquale LR, Thieme H, Iwamoto MA, Park JE et al (1994) Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders (see comments). N Engl J Med 331:1480–1487

    Article  PubMed  CAS  Google Scholar 

  5. Aiello LP, Northrup JM, Keyt BA, Takagi H, Iwamoto MA (1995a) Hypoxic regulation of vascular endothelial growth factor in retinal cells. Arch Ophthalmol 113:1538–1544

    PubMed  CAS  Google Scholar 

  6. Aiello LP, Pierce EA, Foley ED, Takagi H, Chen H, Riddle L, Ferrara N, King GL, Smith LE (1995b) Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGFreceptor chimeric proteins. Proc Natl Acad Sci USA 92:10457–10461

    Article  PubMed  CAS  Google Scholar 

  7. Alon T, Hemo I, Itin A, Pe’er J, Stone J, Keshet E (1995) Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nature Medicine 1:1024–1028

    Article  PubMed  CAS  Google Scholar 

  8. Arosio M, Cortelazzi D, Persani L, Palmieri E, Casati G, Baggiani AM, Gambino G, Beck-Peccoz P (1995) Circulating levels of growth hormone, insulin-like growth factor-I and prolactin in normal, growth retarded and anencephalic human fetuses. J Endocrinol Invest 18:346–353

    PubMed  CAS  Google Scholar 

  9. Ashton IK, Zapf J, Einschenk I, MacKenzie IZ (1985) Insulin-like growth factors (IGF) 1 and 2 in human foetal plasma and relationship to gestational age and foetal size during midpregnancy. Acta Endocrinol (Copenh) 110:558–563

    CAS  Google Scholar 

  10. Ashton N (1966) Oxygen and the growth and development of retinal vessels. In vivo and in vitro studies. The XX Francis I. Proctor Lecture. Am J Ophthalmol 62:412–435

    PubMed  CAS  Google Scholar 

  11. Ashton N, Ward B, Serpell G (1954) Effect of oxygen on developing retinal vessels with particular reference to the problem of retrolental fibroplasia. Br J Ophthalmol 38: 397–432

    Article  PubMed  CAS  Google Scholar 

  12. Campbell K (1951) Intensive oxygen therapy as a possible cause of retrolental fibroplasia: a clinical approach. Med J Aust 2:48–50

    PubMed  CAS  Google Scholar 

  13. Chan-Ling T, Tout S, Hollander H, Stone J (1992) Vascular changes and their mechanisms in the feline model of retinopathy of prematurity. Invest Ophthalmol Vis Sci 33: 2128–2147

    PubMed  CAS  Google Scholar 

  14. Crosse VM, Evans PJ (1952) Prevention of retrolental fibroplasia. Arch Ophthalmol 48:83–87

    CAS  Google Scholar 

  15. D’Ercole AJ, Underwood LE (1985) Somatomedin in fetal growth. Pediatr Pulmonol 1:S99–S106

    Article  PubMed  CAS  Google Scholar 

  16. D’Ercole AJ, Hill DJ, Strain AJ, Underwood LE (1986) Tissue and plasma somatomedin-C/insulin-like growth factor I concentrations in the human fetus during the first half of gestation. Pediatr Res 20:253–255

    Article  PubMed  CAS  Google Scholar 

  17. D’Ercole AJ, Ye P, O’Kusky JR (2002) Mutant mouse models of insulin-like growth factor actions in the central nervous system. Neuropeptides 36:209–220

    Article  PubMed  CAS  Google Scholar 

  18. Donahue ML, Phelps DL, Watkins RH, LoMonaco MB, Horowitz S (1996) Retinal vascular endothelial growth factor (VEGF) mRNA expression is altered in relation to neovascularization in oxygen induced retinopathy. Curr Eye Res 15:175–184

    PubMed  CAS  Google Scholar 

  19. Doublier S, Duyckaerts C, Seurin D, Binoux M (2000) Impaired brain development and hydrocephalus in a line of transgenic mice with liver-specific expression of human insulin-like growth factor binding protein-1. Growth Horm IGF Res 10:267–274

    Article  PubMed  CAS  Google Scholar 

  20. Fant M, Salafia C, Baxter RC, Schwander J, Vogel C, Pezzullo J, Moya F (1993) Circulating levels of IGFs and IGF binding proteins in human cord serum: relationships to intrauterine growth. Regul Pept 48:29–39

    Article  PubMed  CAS  Google Scholar 

  21. Ferrara N, Henzel W (1989) Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem Biophys Res Commun 161:851–858

    Article  PubMed  CAS  Google Scholar 

  22. Flynn JT (1983) Acute proliferative retrolental fibroplasia: multivariate risk analysis. Trans Am Ophthalmol Soc 81: 549–591

    PubMed  CAS  Google Scholar 

  23. Flynn JT, Bancalari E (2000) On “supplemental therapeutic oxygen for prethreshold retinopathy of prematurity (STOPROP), a randomized, controlled trial. I: Primary outcomes” (editorial). J AAPOS Am Assoc Pediatr Ophthalmol Strab 4:65–66

    Article  CAS  Google Scholar 

  24. Foley TP Jr, DePhilip R, Perricelli A, Miller A (1980) Low somatomedin activity in cord serum from infants with intrauterine growth retardation. J Pediatr 96:605–610

    Article  PubMed  CAS  Google Scholar 

  25. Folkman J, Klagsbrun M (1987) Angiogenic factors. Science 235:442–446

    Article  PubMed  CAS  Google Scholar 

  26. Foos R, Kopelow S (1973) Development of retinal vasculature in prenatal infants. Surv Ophthalmol 18:117–127

    Google Scholar 

  27. Fulton AB, Hansen RM, Petersen RA, Vanderveen DK (2001) The rod photoreceptors in retinopathy of prematurity: an electroretinographic study. Arch Ophthalmol 119: 499–505

    PubMed  CAS  Google Scholar 

  28. Giudice LC, de Zegher F, Gargosky SE, Dsupin BA, de las Fuentes L, Crystal RA, Hintz RL, Rosenfeld RG (1995) Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth. J Clin Endocrinol Metab 80:1548–1555

    Article  PubMed  CAS  Google Scholar 

  29. Gluckman PD, Butler JH (1983) Parturition-related changes in insulin-like growth factors-I and-II in the perinatal lamb. J Endocrinol 99:223–232

    PubMed  CAS  Google Scholar 

  30. Gluckman PD, Johnson-Barrett JJ, Butler JH, Edgar BW, Gunn TR (1983) Studies of insulin-like growth factor-I and-II by specific radioligand assays in umbilical cord blood. Clin Endocrinol (Oxf) 19:405–413

    CAS  Google Scholar 

  31. Hellstrom A, Perruzzi C, Ju M, Engstrom E, Hard AL, Liu JL, Albertsson-Wikland K, Carlsson B, Niklasson A, Sjodell L et al (2001a) Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity. Proc Natl Acad Sci USA 98:5804–5808

    Article  PubMed  CAS  Google Scholar 

  32. Hellstrom A, Perruzzi C, Ju M, Engstrom E, Hard A-L, Liu JL, Albertsson-Wikland K, Carlsson B, Niklasson A, Sjodell L et al (2001b) Low IGF-I suppresses VEGF-survival signaling in retinal endothelial cells: direct correlation with clinical retinopathy of prematurity. Proc Natl Acad Sci USA 98:5804–5808

    Article  PubMed  CAS  Google Scholar 

  33. Hellstrom A, Carlsson B, Niklasson A, Segnestam K, Boguszewski M, de Lacerda L, Savage M, Svensson E, Smith L, Weinberger D et al (2002) IGF-I is critical for normal vascularization of the human retina. J Clin Endocrinol Metab 87:3413–3416

    Article  PubMed  CAS  Google Scholar 

  34. Hellstrom A, Engstrom E, Hard AL, Albertsson-Wikland K, Carlsson B, Niklasson A, Lofqvist C, Svensson E, Holm S, Ewald U et al (2003) Postnatal serum insulin-like growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth. Pediatrics 112:1016–1020

    Article  PubMed  Google Scholar 

  35. Hikino S, Ihara K, Yamamoto J, Takahata Y, Nakayama H, Kinukawa N, Narazaki Y, Hara T (2001) Physical growth and retinopathy in preterm infants: involvement of IGF-I and GH. Pediatr Res 50:732–736

    Article  PubMed  CAS  Google Scholar 

  36. Kim KJ, Li B, Winer J, Armanini M, Gillett N, Phillips HS, Ferrara N (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362:841–844

    Article  PubMed  CAS  Google Scholar 

  37. Kinsey VE, Arnold HJ, Kalina RE, Stern L, Stahlman M, Odell G, Driscoll JM Jr, Elliott JH, Payne J, Patz A (1977) PaO2 levels and retrolental fibroplasia: a report of the cooperative study. Pediatrics 60:655–668

    PubMed  CAS  Google Scholar 

  38. Knighton D, Hunt T, Scheuenstuhl H(1993) Oxygen tension regulates the expression of angiogenesis by macrophages. Science 221:1283–1285

    Article  Google Scholar 

  39. Kondo T, Vicent D, Suzuma K, Yanagisawa M, King GL, Holzenberger M, Kahn CR (2003) Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization. J Clin Invest 111:1835–1842

    Article  PubMed  CAS  Google Scholar 

  40. Kubota T, Kamada S, Taguchi M, Aso T (1992) Determination of insulin-like growth factor-2 in feto-maternal circulation during human pregnancy. Acta Endocrinol (Copenh) 127:359–365

    CAS  Google Scholar 

  41. Langford K, Blum W, Nicolaides K, Jones J, McGregor A, Miell J (1994) The pathophysiology of the insulin-like growth factor axis in fetal growth failure: a basis for programming by undernutrition? Eur J Clin Invest 24:851–856

    PubMed  CAS  Google Scholar 

  42. Langford K, Nicolaides K, Miell JP (1998) Maternal and fetal insulin-like growth factors and their binding proteins in the second and third trimesters of human pregnancy. Hum Reprod 13:1389–1393

    Article  PubMed  CAS  Google Scholar 

  43. Lassarre C, Hardouin S, Daffos F, Forestier F, Frankenne F, Binoux M (1991) Serum insulin-like growth factors and insulin-like growth factor binding proteins in the human fetus. Relationships with growth in normal subjects and in subjects with intrauterine growth retardation. Pediatr Res 29:219–225

    Article  PubMed  CAS  Google Scholar 

  44. Lineham JD, Smith RM, Dahlenburg GW, King RA, Haslam RR, Stuart MC, Faull L (1986) Circulating insulin-like growth factor I levels in newborn premature and full-term infants followed longitudinally. Early Hum Dev 13:37–46

    Article  PubMed  CAS  Google Scholar 

  45. McLeod D, Crone S, Lutty G (1996) Vasoproliferation in the neonatal dog model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci 37:1322–1333

    PubMed  CAS  Google Scholar 

  46. Michaelson I (1948) the mode of development of the vascular system of the retina, with some observations in its significance for certain retinal diseases. Trans Ophthalmol Soc UK 68:137–180

    Google Scholar 

  47. Miell JP, Jauniaux E, Langford KS, Westwood M, White A, Jones JS (1997) Insulin-like growth factor binding protein concentration and post-translational modification in embryological fluid. Mol Hum Reprod 3:343–349

    Article  PubMed  CAS  Google Scholar 

  48. Miller JW, Adamis AP, Shima DT, D’Amore PA, Moulton RS, O’Reilly MS, Folkman J, Dvorak HF, Brown LF, Berse B et al (1994) Vascular endothelial growth factor/vascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Am J Pathol 145:574–584

    PubMed  CAS  Google Scholar 

  49. Nieto-Diaz A, Villar J, Matorras-Weinig R, Valenzuela-Ruiz P (1996) Intrauterine growth retardation at term: association between anthropometric and endocrine parameters. Acta Obstet Gynecol Scand 75:127–131

    PubMed  CAS  Google Scholar 

  50. Ostlund E, Bang P, Hagenas L, Fried G (1997) Insulin-like growth factor I in fetal serum obtained by cordocentesis is correlated with intrauterine growth retardation. Hum Reprod 12:840–844

    Article  PubMed  CAS  Google Scholar 

  51. Patz A (1982) Clinical and experimental studies on retinal neovascularization. Am J Ophthalmol 94:715–743

    Article  PubMed  CAS  Google Scholar 

  52. Patz A, Hoeck LE, DeLaCruz E (1952) Studies on the effect of high oxygen administration in retrolental fibroplasia. I. Nursery observations. Am J Ophthalmol 35:1248–1252

    PubMed  CAS  Google Scholar 

  53. Penn JS, Tolman BL, Lowery LA (1993) Variable oxygen exposure causes preretinal neovascularization in the newborn rat. Invest Ophthalmol Vis Sci 34:576–585

    PubMed  CAS  Google Scholar 

  54. Penn JS, Tolman BL, Henry MM (1994) Oxygen-induced retinopathy in the rat: relationship of retinal nonperfusion to subsequent neovascularization. Invest Ophthalmol Vis Sci 35:3429–3435

    PubMed  CAS  Google Scholar 

  55. Pierce EA, Avery RL, Foley ED, Aiello LP, Smith LE (1995) Vascular endothelial growth factor/vascular permeability factor expression in amouse model of retinal neovascularization. Proc Natl Acad Sci USA 92:905–909

    Article  PubMed  CAS  Google Scholar 

  56. Pierce EA, Foley ED, Smith LE (1996) Regulation of vascular endothelial growth factor by oxygen in a model of retinopathy of prematurity (see comments; published erratum appears in Arch Ophthalmol 1997, 115:427). Arch Ophthalmol 114:1219–1228

    PubMed  CAS  Google Scholar 

  57. Plate KH, Breier G, Weich HA, Risau W (1992) Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359:845–848

    Article  PubMed  CAS  Google Scholar 

  58. Popken GJ, Hodge RD, Ye P, Zhang J, Ng W, O’Kusky JR, D’Ercole AJ (2004) In vivo effects of insulin-like growth factor-I (IGF-I) on prenatal and early postnatal development of the central nervous system. Eur J Neurosci 19:2056–2068

    Article  PubMed  Google Scholar 

  59. Poulsen JE (1953) Recovery from retinopathy in a case of diabetes with Simmonds’ disease. Diabetes 2:7–12

    PubMed  CAS  Google Scholar 

  60. Reece EA, Wiznitzer A, Le E, Homko CJ, Behrman H, Spencer EM (1994) The relation between human fetal growth and fetal blood levels of insulin-like growth factors I and II, their binding proteins, and receptors. Obstet Gynecol 84:88–95

    PubMed  CAS  Google Scholar 

  61. Robinson GS, Pierce EA, Rook SL, Foley E, Webb R, Smith LE (1996) Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy. Proc Natl Acad Sci USA 93:4851–4856

    Article  PubMed  CAS  Google Scholar 

  62. Roth AM (1977) Retinal vascular development in premature infants. Am J Ophthalmol 84:636–640

    PubMed  CAS  Google Scholar 

  63. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF (1983) Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid. Science 219:983–985

    Article  PubMed  CAS  Google Scholar 

  64. Sharp PS, Fallon TJ, Brazier OJ, Sandler L, Joplin GF, Kohner EM (1987) Long-term follow-up of patients who underwent yttrium-90 pituitary implantation for treatment of proliferative diabetic retinopathy. Diabetologia 30:199–207

    Article  PubMed  CAS  Google Scholar 

  65. Shih SC, Ju M, Liu N, Smith LE (2003) Selective stimulation of VEGFR-1 prevents oxygen-induced retinal vascular degeneration in retinopathy of prematurity. J Clin Invest 112:50–57

    Article  PubMed  CAS  Google Scholar 

  66. Shweiki D, Itin A, Soffer D, Keshet E (1992) Vascular endothelial growth factor induced by hypoxiamaymediate hypoxia-initiated angiogenesis. Nature 359:843–845

    Article  PubMed  CAS  Google Scholar 

  67. Silverman WA (1980) Retrolental fibroplasia: a modern parable. Grune and Stratton, New York

    Google Scholar 

  68. Smith LE, Wesolowski E, McLellan A, Kostyk SK, D’Amato R, Sullivan R, D’Amore PA (1994) Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci 35:101–111

    PubMed  CAS  Google Scholar 

  69. Smith LE, Kopchick JJ, Chen W, Knapp J, Kinose F, Daley D, Foley E, Smith RG, Schaeffer JM (1997a) Essential role of growth hormone in ischemia-induced retinal neovascularization. Science 276:1706–1709

    Article  PubMed  CAS  Google Scholar 

  70. Smith WJ, Underwood LE, Keyes L, Clemmons DR (1997b) Use of insulin-like growth factor I (IGF-I) and IGF-binding protein measurements to monitor feeding of premature infants. J Clin Endocrinol Metab 82:3982–3988

    Article  PubMed  CAS  Google Scholar 

  71. Smith LE, Shen W, Perruzzi C, Soker S, Kinose F, Xu X, Robinson G, Driver S, Bischoff J, Zhang B et al (1999) Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor. Nature Medicine 5:1390–1395

    Article  PubMed  CAS  Google Scholar 

  72. Stone J, Itin A, Alon T, Pe’er J, Gnessin H, Chan-Ling T, Keshet E (1995) Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia. J Neurosci 15:4738–4747

    PubMed  CAS  Google Scholar 

  73. Stone J, Chan-Ling T, Pe’er J, Itin A, Gnessin H, Keshet E (1996) Roles of vascular endothelial growth factor and astrocyte degeneration in the genesis of retinopathy of prematurity. Invest Ophthalmol Vis Sci 37:290–299

    PubMed  CAS  Google Scholar 

  74. Verhaeghe J, Van Bree R, Van Herck E, Laureys J, Bouillon R, Van Assche FA (1993) C-peptide, insulin-like growth factors I and II, and insulin-like growth factor binding protein-1 in umbilical cord serum: correlations with birth weight. Am J Obstet Gynecol 169:89–97

    PubMed  CAS  Google Scholar 

  75. Wang HS, Lim J, English J, Irvine L, Chard T (1991) The concentration of insulin-like growth factor-I and insulin-like growth factor-binding protein-1 in human umbilical cord serum at delivery: relation to fetal weight. J Endocrinol 129:459–464

    PubMed  CAS  Google Scholar 

  76. Wright AD, Kohner EM, Oakley NW, Hartog M, Joplin GF, Fraser TR (1969) Serum growth hormone levels and the response of diabetic retinopathy to pituitary ablation. Br Med J 2:346–348

    PubMed  CAS  Google Scholar 

  77. Young TL, Anthony DC, Pierce E, Foley E, Smith LE (1997) Histopathology and vascular endothelial growth factor in untreated and diode laser-treated retinopathy of prematurity. J AAPOS 1:105–110

    PubMed  CAS  Google Scholar 

References

  1. Alfieri MC, Magli A, Chiosi E, De CG (1988) The Annette von Droste-Hulshoff syndrome. Pseudostrabismus due to macular ectopia in retinopathy of prematurity. Ophthalmic Paediatr Genet 9:13–16

    PubMed  CAS  Google Scholar 

  2. Axer-Siegel R, Snir M, Cotlear D et al (2000) Diode laser treatment of posterior retinopathy of prematurity. Br J Ophthalmol 84:1383–1386

    Article  PubMed  CAS  Google Scholar 

  3. Ben Sira I, Nissenkorn I, Kremer I (1988) Retinopathy of prematurity. Surv Ophthalmol 33:1–16

    Google Scholar 

  4. Blodi FC (1955) Symposium: Retrolental fibroplasia (retinopathy of prematurity). Management. Trans Am Acad Ophthalmol Otolaryngol 59:35

    PubMed  CAS  Google Scholar 

  5. Bolton DP, Cross KW (1974) Further observations on cost of preventing retrolental fibroplasia. Lancet 1:445–448

    Article  PubMed  CAS  Google Scholar 

  6. Bossi E, Koerner F (1995) Retinopathy of prematurity. Intensive Care Med 21:241–246

    Article  PubMed  CAS  Google Scholar 

  7. Brennan R, Gnanaraj L, Cottrell DG (2003) Retinopathy of prematurity in practice. I. Screening for threshold disease. Eye 17:183–188

    Article  PubMed  CAS  Google Scholar 

  8. Brooks SE, Johnson M, Wallace DK et al (1999) Treatment outcome in fellow eyes after laser photocoagulation for retinopathy of prematurity. Am J Ophthalmol 127:56–61

    Article  PubMed  CAS  Google Scholar 

  9. Bullard SR, Donahue SP, Feman SS et al (1999) The decreasing incidence and severity of retinopathy of prematurity. J AAPOS 3:46–52

    PubMed  CAS  Google Scholar 

  10. Burgess P, Johnson A (1991) Ocular defects in infants of extremely low birth weight and low gestational age. Br J Ophthalmol 75:84–87

    Article  PubMed  CAS  Google Scholar 

  11. Caflisch SR, Bucher HU, Santo B et al (1998) Ophthalmologische Störungen ehemals extrem kleiner Frühgeborener im Alter von 10 Jahren. Monatsschr Kinderheilkd 146:230–234

    Article  Google Scholar 

  12. Cats BP, Tan KE (1989) Prematures with and without regressed retinopathy of prematurity: comparison of longterm (6–10 years) ophthalmological morbidity. J Pediatr Ophthalmol Strabismus 26:271–275

    PubMed  CAS  Google Scholar 

  13. Clark DI, Laws F, Wood ICJ, Laws D (1996) Axial growth of the eye and refractive error following retinopathy of prematurity (ROP)-a longitudinal study. Invest Ophthalmol Vis Sci 37:370

    Google Scholar 

  14. Clemens S, Eckardt C, Gerding H et al (1999) Ophthalmological screening studies in newborn infants. German Ophthalmological Society. Ophthalmologe 96:257–263

    Article  PubMed  CAS  Google Scholar 

  15. Committee on Fetus and Newborn (1985) Vitamin E and the prevention of retinopathy of prematurity. Pediatrics 76:315–316

    Google Scholar 

  16. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1988) Multicenter trial of cryotherapy for retinopathy of prematurity. Preliminary results. Arch Ophthalmol 106:471–479

    Google Scholar 

  17. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1990) Multicenter trial of cryotherapy for retinopathy of prematurity. Three-month outcome. Arch Ophthalmol 108:195–204

    Google Scholar 

  18. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1991) Palmer EA, Flynn JT, Hardy RJ et al. Incidence and early course of retinopathy of prematurity. Ophthalmology 98:1628–1640

    Google Scholar 

  19. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1992) Gilbert WS, Dobson V, Quinn GE, Reynolds J et al. The correlation of visual function with posterior retinal structure in severe retinopathy of prematurity. Arch Ophthalmol 110:625–631

    Google Scholar 

  20. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1992) Quinn GE, Dobson V, Repka MX et al. Development of myopia in infants with birth weights less than 1251 grams. Ophthalmology 99:329–340

    Google Scholar 

  21. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1994) The natural ocular outcome of premature birth and retinopathy. Status at 1 year. Arch Ophthalmol 112:903–912

    Google Scholar 

  22. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1994) Dobson V, Quinn GE, Summers CG et al. Effect of acute-phase retinopathy of prematurity on grating acuity development in the very low birth weight infant. Invest Ophthalmol Vis Sci 35:4236–4244

    Google Scholar 

  23. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1995) Quinn GE, Dobson V, Biglan A et al. Correlation of retinopathy of prematurity in fellow eyes in the cryotherapy for retinopathy of prematurity study. Arch Ophthalmol 113:469–473

    Google Scholar 

  24. Cryotherapy for Retinopathy of Prematurity Cooperative Group (2001) Multicenter Trial of Cryotherapy for Retinopathy of Prematurity: ophthalmological outcomes at 10 years. Arch Ophthalmol 119:1110–1118

    Google Scholar 

  25. Cryotherapy for Retinopathy of Prematurity Cooperative Group (2001) Contrast sensitivity at age 10 years in children who had threshold retinopathy of prematurity. Arch Ophthalmol 119:1129–1133

    Google Scholar 

  26. Cryotherapy for Retinopathy of Prematurity Cooperative Group (2001) Effect of retinal ablative therapy for threshold retinopathy of prematurity: results of Goldmann perimetry at the age of 10 years. Arch Ophthalmol 119:1120–1125

    Google Scholar 

  27. Cryotherapy for Retinopathy of Prematurity Cooperative Group (2005) Palmer EA, Hardy RJ, Dobson V et al. 15-year outcomes following threshold retinopathy of prematurity: final results from the multicenter trial of cryotherapy for retinopathy of prematurity. Arch Ophthalmol 123:311–318

    Google Scholar 

  28. Dogru M, Shirabe H, Nakamura M et al (1999) Development of grating acuity in infants with Retinopathy of Prematurity. Acta Ophthalmol Scand 77:72–75

    Article  PubMed  CAS  Google Scholar 

  29. Early Treatment for Retinopathy of prematurity Cooperative Group (2003) Revised indications for the treatment of Retinopathy of Prematurity. Results of the early treatment for Retinopathy of prematurity randomized trial. Arch Ophthalmol 121:1684–1696

    Article  PubMed  CAS  Google Scholar 

  30. Fielder AR, Shaw DE, Robinson J, Ng YK (1992) Natural history of retinopathy of prematurity: a prospective study. Eye 6:233–242

    PubMed  Google Scholar 

  31. Fledelius HC (1976) Prematurity and the eye. Ophthalmic 10-year follow-up of children of low and normal birth weight. Acta Ophthalmol Suppl 128:3–245

    PubMed  CAS  Google Scholar 

  32. Fledelius HC (1996) Pre-term delivery and subsequent ocular development. A 7–10 year follow-up of children screened 1982–1984 for ROP. 1) Visual function, slit-lamp findings, and fundus appearance. Acta Ophthalmol Scand 74:288–293

    PubMed  CAS  Google Scholar 

  33. Fledelius HC (1996) Pre-term delivery and subsequent ocular development. A 7–10 year follow-up of children screened 1982–1984 for ROP. 4) Oculometric-and other metric considerations. Acta Ophthalmol Scand 74:301–305

    PubMed  CAS  Google Scholar 

  34. Flynn JT, Bancalari E, Bachynski BN et al (1987) Retinopathy of prematurity. Diagnosis, severity, and natural history. Ophthalmology 94:620–629

    PubMed  CAS  Google Scholar 

  35. Foroozan R, Connolly BP, Tasman WS (2001) Outcomes after laser therapy for threshold retinopathy of prematurity. Ophthalmology 108:1644–16446

    Article  PubMed  CAS  Google Scholar 

  36. Gallo JE, Lennerstrand G (1991) A population-based study of ocular abnormalities in premature children aged 5 to 10 years. Am J Ophthalmol 111:539–547

    PubMed  CAS  Google Scholar 

  37. Gaynon MW, Stevenson DK, Sunshine P et al (1997) Supplemental oxygen may decrease progression of prethreshold disease to threshold retinopathy of prematurity. J Perinatol 17:434–438

    PubMed  CAS  Google Scholar 

  38. Gibson DL, Sheps SB, Uh SH et al (1990) Retinopathy of prematurity-induced blindness: birth weight-specific survival and the new epidemic. Pediatrics 86:405–412

    PubMed  CAS  Google Scholar 

  39. Gilbert C, Rahi J, Eckstein M et al (1997) Retinopathy of prematurity inmiddle-income countries. Lancet 350:12–14

    Article  PubMed  CAS  Google Scholar 

  40. Goggin M, O’Keefe M (1993) Diode laser for retinopathy of prematurity-early outcome. Br J Ophthalmol 77:559–562

    Article  PubMed  CAS  Google Scholar 

  41. Good WV, Hardy RJ, Dobson V et al (2005) Early Treatment for Retinopathy of Prematurity Cooperative Group. The incidence and course of retinopathy of prematurity: findings from the early treatment for retinopathy of prematurity study. Pediatrics 116:15–23

    Article  PubMed  Google Scholar 

  42. Gordon RA, Donzis PB (1986) Myopia associated with retinopathy of prematurity. Ophthalmology 93:1593–1598

    PubMed  CAS  Google Scholar 

  43. Haines L, Fielder AR, Scrivener R et al (2002) Royal College of Paediatrics and Child Health, the Royal College of Ophthalmologists and British Association of Perinatal Medicine. Retinopathy of prematurity in the UK I: the organisation of services for screening and treatment. Eye 16:33–38

    Article  PubMed  CAS  Google Scholar 

  44. Hatfield EM (1972) Blindness in infants and young children. Sight Sav Rev 42:69–89

    PubMed  CAS  Google Scholar 

  45. Hindle NW (1982) Cryotherapy for retinopathy of prematurity: Can J Ophthalmol 17:207–212

    PubMed  CAS  Google Scholar 

  46. Hittner HM, Rhodes LM, McPherson AR (1979) Anterior segment abnormalities in cicatricial retinopathy of prematurity. Ophthalmology 86:803–816

    PubMed  CAS  Google Scholar 

  47. Holmstrom G, el Azazi M, Jacobson L, Lennerstrand G (1993) A population based, prospective study of the development of ROP in prematurely born children in the Stockholm area of Sweden. Br J Ophthalmol 77:417–423

    Article  PubMed  CAS  Google Scholar 

  48. Holmstrom G, el Azazi M, Kugelberg U (1999) Ophthalmological follow up of preterm infants: a population based, prospective study of visual acuity and strabismus. Br J Ophthalmol 83:143–150

    PubMed  CAS  Google Scholar 

  49. Horbar JD, McAuliffe TL, Adler SM et al (1988) Variability in 28-day outcomes for very low birth weight infants: an analysis of 11 neonatal intensive care units. Pediatrics 82: 554–559

    PubMed  CAS  Google Scholar 

  50. Hunter DG, Repka MX (1993) Diode laser photocoagulation for threshold retinopathy of prematurity. A randomized study. Ophthalmology 100:238–244

    PubMed  CAS  Google Scholar 

  51. Isenberg SJ (1986) Macular development in the premature infant. Am J Ophthalmol 101:74–80

    PubMed  CAS  Google Scholar 

  52. International Committee for the Classification of the Late Stages of Retinopathy of Prematurity (1987) An international classification of retinopathy of prematurity. II. The classification of retinal detachment. Arch Ophthalmol 105:906–912

    Google Scholar 

  53. International Committee for the Classification of Retinopathy of Prematurity (1984) An international classification of retinopathy of prematurity. Arch Ophthalmol 102:1130–1134

    Google Scholar 

  54. International Committee for the Classification of Retinopathy of Prematurity (2005) The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol 123:991–999

    Article  Google Scholar 

  55. Jandeck C, Kellner U, Helbig H et al (1995) Natural course of retinal development in preterm infants without threshold retinopathy. Ger J Ophthalmol 4:131–136

    PubMed  CAS  Google Scholar 

  56. Jandeck C (1999) Refraktionsfehler bei Frühgeborenen mit und ohne Koagulationsbehandlung. Orthoptik-Pleoptik 23:25–32

    Google Scholar 

  57. Jandeck C, Kellner U, Heimann H, Foerster MH (2004) Screening for retinopathy of prematurity: results of one centre between 1991 and 2002. Klin Monatsbl Augenheilkd 222:577–585

    Article  Google Scholar 

  58. Jandeck C, Kellner U, Foerster MH (2004) Late retinal detachment in patients born prematurely: outcome of primary pars plana vitrectomy. Arch Ophthalmol 122:61–64

    Article  PubMed  Google Scholar 

  59. Jandeck C, Kellner U, Heimann H, Foerster MH (2005) Comparison of the anatomical and functional outcome after laser or cryotherapy for retinopathy of prematurity (ROP). Ophthalmologe 102:33–38

    Article  PubMed  CAS  Google Scholar 

  60. Keith CG (1982) Visual outcome and effect of treatment in stage III developing retrolental fibroplasia. Br J Ophthalmol 66:446–449

    Article  PubMed  CAS  Google Scholar 

  61. Kellner U, Jandeck C, Helbig H et al (1995) Evaluation of published recommendations for screening studies of retinopathy of prematurity. Ophthalmologe 92:681–684

    PubMed  CAS  Google Scholar 

  62. Kinsey VE (1956) Retrolental fibroplasia; cooperative study of retrolental fibroplasia and the use of oxygen. AMA Arch Ophthalmol 56:481–443

    PubMed  CAS  Google Scholar 

  63. Kumar H, Nainiwal S, Singha U et al (2002) Stress induced by screening for retinopathy of prematurity. J Pediatr Ophthalmol Strabismus 39:349–350

    PubMed  Google Scholar 

  64. Lanman JT, Guy LP, Dancis J (1954) Retrolental fibroplasia and oxygen therapy. J Am Med Assoc 155:223–226

    PubMed  CAS  Google Scholar 

  65. Larsson E, Carle-Petrelius B, Cernerud G et al (2002) Incidence of ROP in two consecutive Swedish population based studies. Br J Ophthalmol 86:1122–1126

    Article  PubMed  CAS  Google Scholar 

  66. Larsson EK, Rydberg AC, Holmstrom GE (2005) A population-based study on the visual outcome in 10-year-old preterm and full-term children. Arch Ophthalmol 123:825–832

    Article  PubMed  Google Scholar 

  67. Laser ROP Study Group (1994) Laser therapy for retinopathy of prematurity. Arch Ophthalmol 112:154–156

    Google Scholar 

  68. Laws DE, Haslett R, Ashby D et al (1994) Axial length biometry in infants with retinopathy of prematurity. Eye 8:427–430

    PubMed  Google Scholar 

  69. Laws DE, Morton C, Weindling M et al (1996) Systemic effects of screening for retinopathy of prematurity. Br J Ophthalmol 80:425–428

    Article  PubMed  CAS  Google Scholar 

  70. Laws F, Laws D, Clark D (1997) Cryotherapy and laser treatment for acute retinopathy of prematurity: refractive outcomes, a longitudinal study. Br J Ophthalmol 81:12–15

    Article  PubMed  CAS  Google Scholar 

  71. Lemons JA, Bauer CR, Oh W et al (2001) Very low birth weight outcomes of the National Institute of Child health and human development neonatal research network, January 1995 through December 1996. NICHD Neonatal Research Network. Pediatrics 107:E1

    Article  PubMed  CAS  Google Scholar 

  72. Machemer R (1993) Late traction detachment in retinopathy of prematurity or ROP-like cases. Graefes Arch Clin Exp Ophthalmol 231:389–394

    Article  PubMed  CAS  Google Scholar 

  73. McDonald AD (1963) Cerebral Palsy in Children of Very Low Birth Weight. Arch Dis Child 38:579–588

    PubMed  CAS  Google Scholar 

  74. McNamara JA, Tasman W, Brown GC, Federman JL (1991) Laser photocoagulation for stage 3+ retinopathy of prematurity. Ophthalmology 98:576–580

    PubMed  CAS  Google Scholar 

  75. Nagata M, Takishima R (1968) One side of the coin of functions of public health nursing-with the establishment of home care helpers. Kango 20:130–134

    PubMed  CAS  Google Scholar 

  76. Ng EY, Connolly BP, McNamara JA et al (2002) A comparison of laser photocoagulation with cryotherapy for threshold retinopathy of prematurity at 10 years: part 1. Visual function and structural outcome. Ophthalmology 109:928–934; discussion 935

    Article  PubMed  Google Scholar 

  77. Nissenkorn I, Yassur Y, Mashkowski D et al (1983) Myopia in premature babies with and without retinopathy of prematurity. Br J Ophthalmol 67:170–173

    Article  PubMed  CAS  Google Scholar 

  78. Nissenkorn I, Kremer I, Gilad E et al (1987) ’Rush’ type retinopathy of prematurity: report of three cases. Br J Ophthalmol 71:559–562

    Article  PubMed  CAS  Google Scholar 

  79. Page JM, Schneeweiss S, Whyte HE, Harvey P (1993) Ocular sequelae in premature infants. Pediatrics 92:787–790

    PubMed  CAS  Google Scholar 

  80. Paysse EA, Lindsey JL, Coats DK et al (1999) Therapeutic outcomes of cryotherapy versus transpupillary diode laser photocoagulation for threshold retinopathy of prematurity. J Aapos 3:234–240

    PubMed  CAS  Google Scholar 

  81. Pearce IA, Pennie FC, Gannon LM et al (1998) Three year visual outcome for treated stage 3 retinopathy of prematurity: cryotherapy versus laser. Br J Ophthalmol 82:1254–1259

    PubMed  CAS  Google Scholar 

  82. Pennefather PM, Clarke MP, Strong NP et al (1995) Ocular outcome in children born before 32 weeks gestation. Eye 9:26–30

    PubMed  Google Scholar 

  83. Pennefather PM, Tin W, Strong NP et al (1997) Refractive errors in children born before 32 weeks gestation. Eye 11:736–743

    PubMed  Google Scholar 

  84. Phelps DL (1981) Retinopathy of prematurity: an estimate of vision loss in the United States 1979. Pediatrics 67: 924–925

    PubMed  CAS  Google Scholar 

  85. Pohlandt F (1998) Premature delivery in borderline viability of the infant. A recommendations of the German Society of Gynecology and Obstetrics, the German Society of Pediatrics and Adolescent Medicine, the German Society of Perinatal Medicine and the Society of Neonatology and Pediatric Intensive Care Medicine. Z Geburtshilfe Neonatol 202:261–263

    PubMed  CAS  Google Scholar 

  86. Pollard ZF (1984) Lensectomy for secondary angle-closure glaucoma in advanced cicatricial retrolental fibroplasia. Ophthalmology 91:395–398

    PubMed  CAS  Google Scholar 

  87. Quinn GE, Johnson L, Abbasi S (1992) Onset of retinopathy of prematurity as related to postnatal and postconceptional age. Br J Ophthalmol 76:284–288

    Article  PubMed  CAS  Google Scholar 

  88. Raju TN, Langenberg P, Bhutani V, Quinn GE (1997) Vitamin E prophylaxis to reduce retinopathy of prematurity: a reappraisal of published trials. J Pediatr 131:844–850

    Article  PubMed  CAS  Google Scholar 

  89. Reynolds JD, Hardy RJ, Kennedy KA et al (1998) Lack of efficacy of light reduction in prevention of prematurity. Light reduction in Retinopathy of Prematurity (Light-ROP) Cooperative Group. N Engl J Med 338:1572–1576

    Article  PubMed  CAS  Google Scholar 

  90. Reynolds JD, Dobson V, Quinn GE et al (2002) CRYO-ROP and LIGHT-ROP Cooperative Study Groups. Evidence-based screening criteria for retinopathy of prematurity: natural history data from the CRYO-ROP and LIGHT-ROP studies. Arch Ophthalmol 120:1470–1476

    PubMed  Google Scholar 

  91. Riise R (1993) Nordic registers of visually impaired children. Scand J Soc Med 21:66–68

    PubMed  CAS  Google Scholar 

  92. Robinson R, O’Keefe M (1993) Follow-up study on premature infants with and without retinopathy of prematurity. Br J Ophthalmol 77:91–94

    Article  PubMed  CAS  Google Scholar 

  93. Rowlands E, Ionides AC, Chinn S et al (2001) Reduced incidence of retinopathy of prematurity. Br J Ophthalmol 85:933–935

    Article  PubMed  CAS  Google Scholar 

  94. Saito Y, Hatsukawa Y, Lewis J M et al (1996) Macular coloboma-like lesions and pigment abnormalities as complications of cryotherapy for retinopathy of prematurity in very low birth-weight infants. Am J Ophthalmol 122:299–308

    PubMed  CAS  Google Scholar 

  95. Schalij-Delfos NE, Zijlmans BL, Wittebol-Post D et al (1996) Screening for retinopathy of prematurity: do former guidelines still apply? J Pediatr Ophthalmol Strabismus 33:35–38

    PubMed  CAS  Google Scholar 

  96. Schalij-Delfos NE, Cats BP (1997) Retinopathy of prematurity: the continuing threat to vision in preterm infants. Dutch survey from 1986 to 1994. Acta Ophthalmol Scand 75:72–75

    PubMed  CAS  Google Scholar 

  97. Schalij-Delfos NE, fort he Dutch working group on ROP (1999): Prematuren retinopathie, richtlijn voor screening. In: Van der Velde (ed): Richtlijn oogheelkunde. Deventer, Uitgava Commissie Kwaliteit van het Nederlands Oogheelkundig Gezelschap

    Google Scholar 

  98. Seiberth V, Linderkamp O, Akkoyun-Vardali I et al (1998) Oxygentherapy inacute retinopathyof prematurity stage 3. Invest Ophthalmol Vis Sci 39:820

    Google Scholar 

  99. Snir M, Nissenkorn I, Sherf I et al (1988) Visual acuity, strabismus, and amblyopia in premature babies with and without retinopathy of prematurity. Ann Ophthalmol 20:256–258

    PubMed  CAS  Google Scholar 

  100. Soll RF (2002) Prophylactic natural surfactant extract for preventing morbidity and mortality in preterm infants (Cochrane review). Cochrane Collaboration: Cochrane Libary. Issue 2 Oxford: Update software

    Google Scholar 

  101. STOP-ROP (2000) Supplemental Therapeutic Oxygen for Prethreshold Retinopathy Of Prematurity, a randomized, controlled trial. I. Primary outcomes. Pediatrics 105:295–310

    Article  Google Scholar 

  102. Steinkuller PG, Du L, Gilbert C et al (1999) Childhood blindness. J Aapos 3:26–32

    Article  PubMed  CAS  Google Scholar 

  103. Tasman W(1969) Retinal detachment in retrolental fibroplasia (RLF). Bibl Ophthalmol 79:371–376

    Google Scholar 

  104. Tasman W (1979) Late complications of retrolental fibroplasia. Ophthalmology 86:1724–1740

    PubMed  CAS  Google Scholar 

  105. Terry TL (1942) Extreme prematurity and fibroblastic overgrowth of persistent vascular sheath behind each crystalline lens. I. Preliminary report. Am J Ophthalmol 25:203–204

    Google Scholar 

  106. Vander JF, Handa J, McNamara JA et al (1997) Early treatment of posterior retinopathy of prematurity: a controlled trial. Ophthalmology 104:1731–1735; discussion 1735–1736

    PubMed  CAS  Google Scholar 

  107. Vrabec TR, McNamara JA, Eagle RC Jr, Tasman W (1994) Cryotherapy for retinopathy of prematurity: a histopathologic comparison of a treated and untreated eye. Ophthalmic Surg 25:38–41

    PubMed  CAS  Google Scholar 

  108. Wallow IHL, Sponsel WE, Stevens TS (1991) Clinicopathologic correlation of diode laser burns in monkeys. Arch Ophthalmol 109:648–653

    PubMed  CAS  Google Scholar 

  109. White JE, Repka MX (1997) Randomized comparison of diode laser photocoagulation versus cryotherapy for threshold retinopathy of prematurity: 3-year outcome. J Pediatr Ophthalmol Strabismus 34:83–87

    PubMed  CAS  Google Scholar 

  110. Yamashita Y (1972) Studies on retinopathy of prematurity. III. Cryocautery for retinopathy of prematurity. Rinsho Ganka 26:385–393

    Google Scholar 

References

  1. Capone A, Trese MT (2001) Lens-sparing vitreous surgery for tractional Stage 4A retinopathy of prematurity retinal detachments. Ophthalmology 108:2068–2070

    Article  PubMed  Google Scholar 

  2. Coats D, Miller A, Brady McCreery K, Holz E, Paysse E (2004) Involution of threshold retinopathy of prematurity after diode laser photocoagulation. Ophthalmology 111: 1894–1898

    Google Scholar 

  3. Cryotherapy for Retinopathy of Prematurity Cooperative Group (2001) Multicenter trial of cryotherapy for retinopathy of prematurity:Ophthalmological outcomes at 10 years. Arch Ophthalmol 119:1110–1118

    Google Scholar 

  4. Early Treatment for Retinopathy of Prematurity Cooperative Group (2003) Revised indications for the treatment of retinopathy of prematurity: results of the early treatment for retinopathy of prematurity randomized trial. Arch Ophthalmol 121:1684–1694

    Article  PubMed  CAS  Google Scholar 

  5. Greven C, Tasman W (1990) Scleral buckling in stages 4B and 5 retinopathy of prematurity. Ophthalmology 97:817–820

    PubMed  CAS  Google Scholar 

  6. Hartnett MI, McColm JR (2004) Retinal features predictive of progressive stage 4 retinopathy of prematurity. Retina 24:237–241

    Article  PubMed  Google Scholar 

  7. Hirose T, Katsumi O, Mehta MC, Schepens CL (1993) Vision in stage 5 retinopathy of prematurity after retinal reattachment by open-sky vitrectomy. Arch Ophthalmol 111:345–349

    PubMed  CAS  Google Scholar 

  8. Hubbard GB, Cherwick H, Burian G (2004) Lens-sparing vitrectomy for stage 4 retinopathy of prematurity. Ophthalmology 111:2274–2277

    Article  PubMed  Google Scholar 

  9. Maguire AM, Trese MT (1992) Lens-sparing vitreoretinal surgery in infants. Arch Ophthalmol 110:284–286

    PubMed  CAS  Google Scholar 

  10. Mandriota SJ, Menoud PA, Pepper MS (1996) Transforming growth factor beta 1 down-regulates vascular endothelial growth factor receptor 2/flk-1 expression in vascular endothelial cells. J Biol Chem 271:11500–11505

    Article  PubMed  CAS  Google Scholar 

  11. Multicenter trial of cryotherapy for retinopathy of prematurity (1990) One-year outcome-structure and function. Cryotherapy for Retinopathy of Prematurity Cooperative Group (1990) Arch Ophthalmol 108:1408–1416

    Google Scholar 

  12. Palmer EA, Flynn JT, Hardy RJ, Phelps DL, Phillips CL, Schaffer DB, Tung B (1991) The cryotherapy for retinopathy of prematurity cooperative group: Incidence and early course of retinopathy of prematurity. Ophthalmology 98:1624–1640

    Google Scholar 

  13. Prenner JL, Capone A, Trese MT (2004) Visual outcomes after lens-sparing vitrectomy for stage 4A retinopathy of prematurity. Ophthalmology 111:2271–2273

    Article  PubMed  Google Scholar 

  14. Saunders RA, Donahue ML, Christmann LM, Pakalnis AV, Tung B, Hardy RJ, Phelps DL (1997) Racial variation in retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol 115: 604–608

    PubMed  CAS  Google Scholar 

  15. Tasman W, Borrone RN, Bolling J (1987) Open sky vitrectomy for total retinal detachment in retinopathy of prematurity. Ophthalmology 94:449–452

    PubMed  CAS  Google Scholar 

  16. Trese MT (1984) Surgical results of Stage V retrolental fibroplasias and timing of surgical repair. Ophthalmology 91:461–466

    PubMed  CAS  Google Scholar 

  17. Trese MT (1987) Surgical therapy for stage V retinopathy of prematurity. A two-step approach. Graefes Arch Clin Exp Ophthalmol 225:266–268

    Article  PubMed  CAS  Google Scholar 

  18. Trese MT (1994) Scleral buckling for retinopathy of prematurity. Ophthalmology 101:23–26

    PubMed  CAS  Google Scholar 

  19. Trese MT, Droste PJ (1998) Long-term postoperative results of a consecutive series of stages 4 and 5 retinopathy of prematurity. Ophthalmology 105:992–997

    Article  PubMed  CAS  Google Scholar 

  20. Zhao S, Overbeek PA (2001) Elevated TGF beta signaling inhibits ocular vascular development. Dev Biol 237:45–53

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Ophthalmology, Children’s Hospital Harvard Medical School, 300 Longwood Avenue, Boston, MA, 02115, USA

    Lois E. H. Smith MD, PhD

  2. Department of Ophthalmology, Campus Benjamin Franklin, Charité Universitätsmedizin, Berlin, Germany

    Claudia Jandeck MD

  3. Department of Ophthalmology, Campus Benjamin Franklin, Humboldt University Berlin, Hindenburgdamm 30, 12200, Berlin, Germany

    Michael H. Foerster MD

  4. William Beaumont Hospital Medical Building, Suite 632, 3535 W. Thirteen Mile Road, Royal Oak, MI, 48073, USA

    Polly Quiram MD, PhD (Associated Retinal Consultants), Michael Lai MD, PhD (Associated Retinal Consultants) & Michael T. Trese MD (Associated Retinal Consultants)

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Editors and Affiliations

  1. Department of Ophthalmology, University of Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany

    Antonia M. Joussen MD, PhD (Professor of Ophthalmology) (Professor of Ophthalmology)

  2. Department of Ophthalmology, Penn State College of Medicine, 500 University, Drive Box 850, Hershey, PA, 17033, USA

    Thomas W. Gardner MD, MS (Professor of Ophthalmology) (Professor of Ophthalmology)

  3. Department of Vitreoretinal Surgery, Center for Ophthalmology, University of Cologne, Joseph-Stelzmann-Straße 9, 50931, Cologne, Germany

    Bernd Kirchhof MD (Professor of Ophthalmology) (Professor of Ophthalmology)

  4. Doheny Eye Institute, University of Southern California, 1450 San Pablo Street, Los Angeles, CA, 90033, USA

    Stephen J. Ryan MD (Professor of Ophthalmology) (Professor of Ophthalmology)

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Smith, L.E.H., Jandeck, C., Foerster, M.H., Quiram, P., Lai, M., Trese, M.T. (2007). Retinopathy of Prematurity. In: Joussen, A.M., Gardner, T.W., Kirchhof, B., Ryan, S.J. (eds) Retinal Vascular Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29542-6_20

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