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Bioengineered Constructs of the Ramus/Condyle Unit

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Contemporary Management of Temporomandibular Disorders

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Abstract

One of the most challenging reconstructions in maxillofacial surgery is that involving the condyle and ramus. Common reconstructive techniques involve either autogenous bone grafting such as costochondral rib grafting, a sliding posterior ramus border osteotomy, microvascular free fibula graft, or alloplastic reconstruction involving either stock or custom total joint replacement. None of these techniques specifically address the articular disc and some address only bone and not soft tissue. Bioengineering, which uses cells, molecules, chemistry, and scaffolds with engineering principles, is now providing novel solutions to complex biological problems.

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Acknowledgments

The authors gratefully acknowledge funding of this work by NIH (grants DE016525 and EB002520).

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Authors and Affiliations

  1. Section of Hospital Dentistry, Division of Oral and Maxillofacial Surgery, Columbia University College of Dental Medicine, New York, NY, USA

    Sidney B. Eisig

  2. New York Presbyterian/Columbia University Medical Center, Morgan Stanley Children’s Hospital of New York-Presbyterian, New York, NY, USA

    Sidney B. Eisig

  3. Division of Oral and Maxillofacial Surgery, New York Presbyterian/Columbia University Medical Center, New York, NY, USA

    Michael Forman

  4. Department of Biomedical Engineering, Fu Foundation School of Engineering and Applied Science, Columbia University, New York, NY, USA

    Gordana Vunjak-Novakovic

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  1. Sidney B. Eisig
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  2. Michael Forman
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Correspondence to Sidney B. Eisig .

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Editors and Affiliations

  1. Oral and Maxillofacial Surgery, San Francisco VA Health Care System, University of California San Francisco, San Francisco, CA, USA

    S. Thaddeus Connelly  & Rebeka G. Silva  & 

  2. Private Practice, Dental Implant and Oral Surgery of San Francisco, San Francisco, CA, USA

    S. Thaddeus Connelly  & Rebeka G. Silva  & 

  3. Department of Biomedical Sciences for Health, Functional Anatomy Research Center (FARC), Universita degli Studi di Milano Functional Anatomy Research Center, Milano, Italy

    Gianluca Martino Tartaglia

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Eisig, S.B., Forman, M., Vunjak-Novakovic, G. (2019). Bioengineered Constructs of the Ramus/Condyle Unit. In: Connelly, S.T., Tartaglia, G.M., Silva, R.G. (eds) Contemporary Management of Temporomandibular Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-99909-8_15

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